Impaired duodenal bicarbonate secretion in diabetic rats. Salutary effect of nitric oxide synthase inhibitor [0.03%]
糖尿病大鼠十二指肠碳酸氢盐分泌障碍一硝酸氧化物合成酶抑制剂的治疗作用
K Takeuchi,T Hirata,R Korolkiewicz et al.
K Takeuchi et al.
We previously reported the impaired HCO3- secretion and the increased mucosal susceptibility to acid in the duodenum of streptozotocin (STZ)-induced diabetic rats. In this study, we investigated the salutary effect of the NO synthase inhibi...
Stimulatory effect of PACAP on gastroduodenal bicarbonate secretion in rats [0.03%]
PACAP对大鼠胃十二指肠分泌氢氧根离子的促作用
K Takeuchi,K Yagi,M Kitamura et al.
K Takeuchi et al.
The effects of pituitary adenylate cyclase activating polypeptides (PACAPs) on gastroduodenal HCO3- secretion were investigated in anesthetized rats and compared with those of vasoactive intestinal polypeptide (VIP). Under urethane anesthes...
Effect of somatostatin immunoneutralization on gastric acid and pancreatic enzyme secretion in anesthetized rats [0.03%]
免疫中和 somatostatin 对麻醉大鼠胃酸及胰酶分泌的影响
G Varga,I Kisfalvi Jr,K Kordás et al.
G Varga et al.
The involvement of somatostatin in urethane-anesthesia-evoked suppression of gastric acid secretion has been described. The present study has examined the role of endogenous somatostatin in diminished pancreatic enzyme secretion during anes...
The effect of L-arginine/nitric oxide pathway on salivary amylase secretion in conscious rats [0.03%]
L-精氨酸/一氧化氮通路对清醒大鼠唾液淀粉酶分泌的影响
Z Lohinai,B Burghardt,T Zelles et al.
Z Lohinai et al.
In a recent study we have demonstrated the presence of nitric oxide synthase immunoreactive neurons and also perivascular, periacinar and periductal nerve fibres in feline submandibular salivary gland. The role of nitric oxide (NO) in saliv...
Nitric oxide synthase, oxytocin and vasopressin immunoreactivities in the paraventricular, supraoptic and vagal nuclei of the ferret [0.03%]
雪貂下视丘室旁核、近中缝核及迷走神经核一氧化氮合酶、催产素和血管加压素免疫反应性的分布特点
B I Gustafsson,L D Oland,J S Davison
B I Gustafsson
Cyclooxygenase inhibition in the dorsal vagal complex of the rat evokes increases in gastric motor function [0.03%]
大鼠背迷走神经复合物中环氧合酶的抑制可增强胃动力功能
Z K Krowicki,N A Nathan,P J Hornby
Z K Krowicki
To characterize the involvement of brainstem cyclooxygenase (COX) in the vagal control of gastric motor function, tolmetin, a reversible COX inhibitor, was applied to the surface of the dorsal medulla oblongata or microinjected into the dor...
Evidence for a dual mechanism of gastric motor responses to intravenously administered endothelin-1 in anesthetized rats [0.03%]
有关内皮素-1通过双重机制引起麻醉大鼠胃运动反应的证据
Z K Krowicki,P J Hornby
Z K Krowicki
We have recently reported that endothelin-1 (ET-1), administered intracisternally or microinjected into the DVC of rats, increases gastric motor function via vagal pathways. To determine whether circulating ET-1 acts peripherally or central...
Different mechanisms are responsible for the contractile effects of histaminergic compounds on isolated intestinal smooth muscle cells [0.03%]
组胺类似物诱导的肠道平滑肌收缩作用的不同机制研究
G Bertaccini,G Morini,G Coruzzi
G Bertaccini
The effects of histamine and dimaprit on intestinal smooth muscle contractility were investigated on isolated cells from longitudinal muscle of the guinea pig ileum. Both histamine (10(-14)-10(-10) M) and dimaprit (10(-13)-10(-10) M) exerte...
A study of the actions of naloxone and morphine on gastric acid secretion and gastric mucosal damage in the rat [0.03%]
纳洛酮和吗啡对大鼠胃酸分泌及胃粘膜损伤作用的实验研究
A Debreceni,B Debreceni,G Mózsik
A Debreceni
There exists a considerable controversy in the literature with regard to the effect of either opiate receptor blockade or that of morphine in different gastric and intestinal ulcer models in the rat. We performed experiments to evaluate the...
Direct cellular effects of some mediators, hormones and growth factor-like agents on denervated (isolated) rat gastric mucosal cells [0.03%]
某些介质、激素和类似生长因子的物质对去神经支配的大鼠胃粘膜细胞的直接作用
B Bódis,O Karádi,L Nagy et al.
B Bódis et al.
The brain-gut axis has an important role in the mechanism of gastric cytoprotection in vivo. The aim of this study was to evaluate the in vitro effect of protective agents without any central and peripheral innervation. A mixed population o...