The key-role of vagal nerve and adrenals in the cytoprotection and general gastric mucosal integrity [0.03%]
迷走神经和肾上腺在细胞保护和胃粘膜整体完整性中的关键作用
G Mózsik,O Karádi,Király A et al.
G Mózsik et al.
Background: Our laboratory group observed earlier that the gastric mucosal cytoprotective effect of prostacyclin (PGI(2)) disappeared after surgical vagotomy in rats. Similarly to this, the beta-carotene induced gastric c...
Pharmacological analysis of wine-stimulated gastric acid secretion in dogs [0.03%]
有关葡萄酒刺激的胃酸分泌的药理学分析（狗模型）
Y Tsukimi,T Ogawa,S Okabe
Y Tsukimi
Wine apparently stimulates gastric acid secretion both in man and animals, yet the underlying mechanism remains unclear. The present study was attempted to clarify the pharmacological properties involved in gastric acid secretion stimulated...
Neonatal monosodium glutamate treatment abolishes both delta opioid receptor-induced and alpha-2 adrenoceptor-mediated gastroprotection in the lower brainstem in rats [0.03%]
新生儿单钠谷氨酸治疗消除了大鼠下脑干中δ型阿片受体和α-2肾上腺素受体介导的胃保护作用
A Z Rónai,K Gyires,I Barna et al.
A Z Rónai et al.
Neonatal monosodium glutamate treatment reduced immunoreactive beta-endorphin content in the mediobasal hypothalamus by 50% in adult, male Wistar rats as compared to hypertonic saline-treated littermates; there was also a moderate (approx. ...
Involvement of the opioid system in the central antisecretory action of alpha-2 adrenoceptor agonists in rat [0.03%]
阿片受体在α-2肾上腺素受体激动剂中枢抗分泌作用中的参与效应研究
K Müllner,K Gyires,S Furst
K Müllner
The aim of the present study was to analyse the role of the central alpha-2 adrenoceptors in the regulation of gastric acid secretion in pylorus ligated rats. It was found that the intracerebroventricularly (icv.) injected presynaptic alpha...
Gastroprotective action of glucocorticoids during the formation and the healing of indomethacin-induced gastric erosions in rats [0.03%]
糖皮质激素在吲哚美辛致大鼠胃糜烂形成和修复过程中的保护作用
L Filaretova,T Podvigina,T Bagaeva et al.
L Filaretova et al.
The aim of the present study consisted of the investigation of glucocorticoid role in the formation and the healing of indomethacin-induced (25 mg/kg, s.c.) gastric erosions in rats. The effect of deficiency of glucocorticoid production fol...
Failure of capsaicin-containing red pepper sauce suspension to induce esophageal motility response in patients with Barrett's esophagus [0.03%]
辣椒素红椒酱悬液不能诱导巴雷特食管患者的食道运动反应
A Király,G Süto,J Czimmer et al.
A Király et al.
The physiologic importance of afferent sensory pathways in the esophageal motor functions has been recently recognised. Capsaicin-sensitive sensory afferents were shown to play a role in the maintenance of mucosal integrity of the GI tract,...
Activation of central opioid receptors may induce gastric mucosal defence in the rat [0.03%]
中枢阿片受体的激活可诱发大鼠胃粘膜防御功能
K Gyires,K Müllner,A Z Rónai
K Gyires
The effect of different opioid peptides on acidified ethanol- and indomethacin-induced gastric mucosal lesions was studied following intracerebroventricular (i.c.v.) administration. It was found that both the selective delta opioid receptor...
Capsaicin-sensitive afferents and their role in gastroprotection: an update [0.03%]
辣椒素敏感传入及其在胃保护中的作用：最新研究进展
J Szolcsányi,L Barthó
J Szolcsányi
The pivotal role of capsaicin-sensitive peptidergic sensory fibers in the maintenance of gastric mucosal integrity against injurious interventions was suggested by the authors 20 years ago. Since then substantial evidence has accumulated fo...
Further analysis of prostacyclin's effect on rat gastric mucosal nucleic acid content [0.03%]
前列腺素I2对大鼠胃粘膜核酸含量影响的进一步观察
G A Balint
G A Balint
Graded single and multiple oral doses of prostacyclin enhance, in a direct dose-dependent manner, the DNA and RNA content of rat gastric (antral and fundic) mucosa, resulting in a decreased RNA/DNA ratio. This latter phenomenon is a convinc...
Gastric mucosal endogenous prostacyclin levels are different in Brattleboro rats compared with Wistar strain [0.03%]
布拉特伯罗大鼠与威斯特大鼠胃黏膜内源性前列环素水平不同
G A Balint,M Galfi,A Juhasz et al.
G A Balint et al.
Homozygous Brattleboro rats were investigated and compared to normal (physiological) Wistar strain rats regarding their gastric mucosal endogenous prostacyclin (PG-I(2)) level. It seems that the Brattleboro animals have a significantly lowe...
Comparative Study
Journal of physiology, Paris. 2001 Jan-Dec;95(1-6):173-5. DOI:10.1016/s0928-4257(01)00070-5 2001