Physical activity levels of persons with mental illness attending psychiatric rehabilitation programs [0.03%]
精神疾病康复项目的受助人的身体活动水平
Gerald J Jerome,Deborah Rohm Young,Arlene Dalcin et al.
Gerald J Jerome et al.
This study objectively measured physical activity levels in overweight and obese adults with severe mental illness and examined relationships among psychiatric symptoms, cognitive functioning and physical activity. A diverse sample (50% fem...
Impaired regional hemodynamic response in schizophrenia during multiple prefrontal activation tasks: a two-channel near-infrared spectroscopy study [0.03%]
schizophrenia患者在执行多前额叶激活任务时的局部脑血流动力学改变--双通道近红外光谱研究
Koji Ikezawa,Masao Iwase,Ryouhei Ishii et al.
Koji Ikezawa et al.
In schizophrenia, dysfunction of the prefrontal cortex (PFC), regarded as a core feature of the disease, has been investigated by different neuroimaging methods. Near infrared spectroscopy (NIRS), a novel neurophysiological method, is being...
Insulin resistance and secretion in vivo: effects of different antipsychotics in an animal model [0.03%]
不同抗精神病药物对动物模型体内胰岛素抵抗和分泌的影响
Araba F Chintoh,Steve W Mann,Loretta Lam et al.
Araba F Chintoh et al.
Atypical antipsychotics now represent the mainstay of treatment for patients with schizophrenia. Unfortunately, as a class they have also been associated with an increased risk of weight gain and metabolic abnormalities, including type 2 di...
Common effect of antipsychotics on the biosynthesis and regulation of fatty acids and cholesterol supports a key role of lipid homeostasis in schizophrenia [0.03%]
抗精神病药物共同影响脂肪酸和胆固醇的生物合成及调节作用支持脂质稳态在精神分裂症中起关键作用
Mihael H Polymeropoulos,Louis Licamele,Simona Volpi et al.
Mihael H Polymeropoulos et al.
For decades, the dopamine hypothesis has gained the most attention in an attempt to explain the origin and the symptoms of schizophrenia. While this hypothesis offers an explanation for the relationship between psychotic symptoms and dopami...
The case for not combining men and women in neurocognitive studies for schizophrenia [0.03%]
精神分裂症神经认知研究中不分性别的好处
José Jiménez,Adham Mancini-Marïe,Adrianna Mendrek
José Jiménez
Weight gain with clozapine: 8-year cohort naturalistic study among hospitalized Chinese schizophrenia patients [0.03%]
氯氮平所致体重增加的8年队列研究——中国住院精神分裂症患者的自然病程调查
Ya-Mei Bai,Jen-Yeu Chen,Tzu-Ting Chen et al.
Ya-Mei Bai et al.
Objective: Clozapine is associated with significant weight gain. However, it is still debatable whether the majority of weight gain occurs in the early phase of treatment or if weight gain is a persistent side effect. The...
Add-on mirtazapine enhances antipsychotic effect of first generation antipsychotics in schizophrenia: a double-blind, randomized, placebo-controlled trial [0.03%]
奥氮平增效传统抗精神病药治疗精神分裂症的疗效：一项随机双盲安慰剂对照研究
Grigori Joffe,Viatcheslav Terevnikov,Marina Joffe et al.
Grigori Joffe et al.
Background: Mirtazapine, an antidepressant with a broad spectrum of receptor affinity may, if combined with first generation antipsyhotics (FGAs), improve clinical profile of the FGAs. However, potentiation of the antipsy...
Randomized Controlled Trial
Schizophrenia research. 2009 Mar;108(1-3):245-51. DOI:10.1016/j.schres.2008.12.002 2009
Progressive brain structural changes mapped as psychosis develops in 'at risk' individuals [0.03%]
研究绘制"高风险"个体在精神病发作过程中的大脑结构变化图
Daqiang Sun,Lisa Phillips,Dennis Velakoulis et al.
Daqiang Sun et al.
Background: Schizophrenia and related psychoses are associated with brain structural abnormalities. Recent findings in 'at risk' populations have identified progressive changes in various brain regions preceding illness o...
Meta-analysis of the effects of repetitive transcranial magnetic stimulation (rTMS) on negative and positive symptoms in schizophrenia [0.03%]
重复经颅磁刺激(rTMS)对精神分裂症阴性症状和阳性症状影响的荟萃分析研究
Catarina Freitas,Felipe Fregni,Alvaro Pascual-Leone
Catarina Freitas
Background: A growing body of evidence suggests that repetitive transcranial magnetic stimulation (rTMS) can alleviate negative and positive symptoms of refractory schizophrenia. However, trials to date have been small an...
Increased diffusivity in superior temporal gyrus in patients with schizophrenia: a Diffusion Tensor Imaging study [0.03%]
精神分裂症患者颞上回扩散张量成像研究发现异常增高区域
KangUk Lee,Takeshi Yoshida,Marek Kubicki et al.
KangUk Lee et al.
Background: Superior temporal gyrus (STG) volume reduction is one of the most consistent findings in schizophrenia. The goal of this study was to conduct the first Diffusion Tensor Imaging (DTI) study to investigate alter...