The efficacy of lamotrigine in clozapine-resistant schizophrenia: a systematic review and meta-analysis [0.03%]
卡马西平治疗难治性精神分裂症疗效的系统评价和meta分析
Jari Tiihonen,Kristian Wahlbeck,Vesa Kiviniemi
Jari Tiihonen
Background: Clozapine is the drug of choice for patients with unsatisfactory response to routine antipsychotic treatment. Polypharmacy is widely used among patients having clozapine-resistant schizophrenia, although no so...
Differential relationship of frontal pole and whole brain volumetric measures with age in neuroleptic-naïve schizophrenia and healthy subjects [0.03%]
首次使用抗精神病药物的精神分裂症患者与健康受试者海马体积的年龄相关性差异研究
John P John,Paul W Burgess,B S Yashavantha et al.
John P John et al.
Brodmann's area (BA) 10, which occupies the frontal pole (FP) of the human brain, has been proven to play a central role in the executive control of cognitive operations. Previous in vivo morphometric studies of the FP have been limited by ...
Comparative Study
Schizophrenia research. 2009 Apr;109(1-3):148-58. DOI:10.1016/j.schres.2008.12.019 2009
Psychopathology and cognition in divergent functional outcomes in schizophrenia [0.03%]
精神病学和认知在分裂症的功能结局中的作用
R Walter Heinrichs,Narmeen Ammari,Ashley Miles et al.
R Walter Heinrichs et al.
Cognitive performance rather than symptoms, especially positive symptoms, is regarded as the primary predictor of functional outcome in schizophrenia. However, contradictory evidence exists and many studies fail to sample from the extremes ...
Comparative Study
Schizophrenia research. 2009 Apr;109(1-3):46-51. DOI:10.1016/j.schres.2009.01.001 2009
Association of the 5'-upstream regulatory region of the alpha7 nicotinic acetylcholine receptor subunit gene (CHRNA7) with schizophrenia [0.03%]
α7烟碱乙酰胆碱受体亚单位基因（CHRNA7）的5′-上游调控区域与精神分裂症相关性研究
Sarah H Stephens,Judith Logel,Amanda Barton et al.
Sarah H Stephens et al.
Background: The alpha7 neuronal nicotinic acetylcholine receptor subunit gene (CHRNA7) is localized in a chromosomal region (15q14) linked to schizophrenia in multiple independent studies. CHRNA7 was selected as the best ...
Abnormal prefrontal cortical activity and connectivity during response selection in first episode psychosis, chronic schizophrenia, and unaffected siblings of individuals with schizophrenia [0.03%]
首发精神病、慢性精神分裂症和未受影响的精神分裂症患者同胞兄弟姐妹在反应选择过程中的异常前额叶皮层活动及功能连接
Neil D Woodward,Barb Waldie,Baxter Rogers et al.
Neil D Woodward et al.
The search for genes conferring liability for schizophrenia may be aided by the identification of endophenotypes. Response selection is a heritable cognitive function that is impaired in patients with schizophrenia and their unaffected sibl...
Comparative Study
Schizophrenia research. 2009 Apr;109(1-3):182-90. DOI:10.1016/j.schres.2008.11.028 2009
Long-term stability of measuring D(2) receptors in schizophrenia patients treated with antipsychotics [0.03%]
抗精神病药治疗精神分裂症患者长期稳定测量D(2)受体数量变化
Hiroyuki Uchida,Ariel Graff-Guerrero,Benoit H Mulsant et al.
Hiroyuki Uchida et al.
Background: While antipsychotic-free schizophrenia patients showed a high degree of within-subject variability in dopamine D(2) receptor density over 6-24 months, no study has examined the long-term stability of D(2) rece...
Comparative Study
Schizophrenia research. 2009 Apr;109(1-3):130-3. DOI:10.1016/j.schres.2008.12.022 2009
Heart rate variability response to mental arithmetic stress is abnormal in first-degree relatives of individuals with schizophrenia [0.03%]
精神分裂症患者的直系亲属心率变异性应激反应异常
Mariana N Castro,Daniel E Vigo,Elvina M Chu et al.
Mariana N Castro et al.
Background: Schizophrenia patients exhibit an abnormal autonomic response to mental stress. We sought to determine the cardiac autonomic response to mental arithmetic stress in their unaffected first-degree relatives. ...
Comparative Study
Schizophrenia research. 2009 Apr;109(1-3):134-40. DOI:10.1016/j.schres.2008.12.026 2009
Risk factors for suicide in schizophrenia: findings from a Swedish population-based case-control study [0.03%]
一项基于瑞典人口的病例对照研究中精神分裂症自杀危险因素的研究发现
Johan Reutfors,Lena Brandt,Erik G Jönsson et al.
Johan Reutfors et al.
Previous reports regarding risk factors for suicide in schizophrenia have been inconclusive. We performed a matched case-control study of in-patient-treated schizophrenia patients in order to assess the suicide risk associated with socioeco...
A randomized controlled trial of group cognitive-behavioral therapy vs. enhanced supportive therapy for auditory hallucinations [0.03%]
认知行为疗法治疗听觉幻觉的随机对照研究
David L Penn,Piper S Meyer,Elizabeth Evans et al.
David L Penn et al.
There has been little research examining group cognitive-behavioral therapy (CBT) for schizophrenia, especially compared to an active control treatment. The purpose of this study was to investigate the effectiveness of group CBT for auditor...
Randomized Controlled Trial
Schizophrenia research. 2009 Apr;109(1-3):52-9. DOI:10.1016/j.schres.2008.12.009 2009
Childhood trauma and prodromal symptoms among individuals at clinical high risk for psychosis [0.03%]
童年创伤与临床高危个体精神病前驱症状的关系研究
Judy L Thompson,Meredith Kelly,David Kimhy et al.
Judy L Thompson et al.
Introduction: Numerous studies point to an association between childhood trauma and the later development of psychotic illness. However, little is known about the prevalence of childhood trauma and its relationship to att...