Cognitive and antismoking effects of varenicline in patients with schizophrenia or schizoaffective disorder [0.03%]
用于治疗精神分裂症或分裂情感障碍患者的伐尼克兰的认知及抗吸烟作用
Robert C Smith,Jean-Pierre Lindenmayer,John M Davis et al.
Robert C Smith et al.
Objective: Varenicline has been shown to be an effective anti-smoking treatment in smokers without identified psychiatric illness, and the drug's pharmacology suggests possibilities of pro-cognitive effects. However, rece...
Functionally defined regions may aid interpretation of striatal dopamine elevation in schizophrenia [0.03%]
功能区的定义有助于解释精神分裂症纹状体多巴胺升高的现象
Alice Egerton,Philip K McGuire,Oliver D Howes
Alice Egerton
Increased antibodies for the alpha7 subunit of the nicotinic receptor in schizophrenia [0.03%]
精神分裂症患者α7烟碱乙酰胆碱受体亚单位自身抗体水平升高
Michelle J Chandley,Merry N Miller,Christine Newell Kwasigroch et al.
Michelle J Chandley et al.
One of the etiological theories of schizophrenia is dysregulation of the immune system. Autoantibodies specific for the alpha7 subunit of the nicotinic receptor could potentially contribute to the pathophysiology of the disease. In this stu...
Comparative Study
Schizophrenia research. 2009 Apr;109(1-3):98-101. DOI:10.1016/j.schres.2009.01.023 2009
Aripiprazole brain concentration is altered in P-glycoprotein deficient mice [0.03%]
缺乏P-糖蛋白的小鼠脑部阿立哌唑浓度发生变化
Jun-Sheng Wang,Hao-Jie Zhu,Jennifer L Donovan et al.
Jun-Sheng Wang et al.
P-glycoprotein (P-gp) is a transporter that mediates the tissue disposition of numerous drugs. To evaluate the role of P-glycoprotein (P-gp) in aripiprazole tissue distribution and penetration across the blood-brain barrier, mice deficient ...
Association study of the G72 gene with schizophrenia in a Japanese population: a multicenter study [0.03%]
日本人群G72基因与精神分裂症的关联研究：多中心研究
Kazutaka Ohi,Ryota Hashimoto,Yuka Yasuda et al.
Kazutaka Ohi et al.
G72 is one of the most widely tested genes for association with schizophrenia. As G72 activates the D-amino acid oxidase (DAO), G72 is termed D-amino acid oxidase activator (DAOA). The aim of this study is to investigate the association bet...
Comparative Study
Schizophrenia research. 2009 Apr;109(1-3):80-5. DOI:10.1016/j.schres.2009.01.019 2009
A stress-coping model of mental illness stigma: II. Emotional stress responses, coping behavior and outcome [0.03%]
精神疾病污名化的应对压力模型（二）：情绪应激反应、应对行为及结果
Nicolas Rüsch,Patrick W Corrigan,Karina Powell et al.
Nicolas Rüsch et al.
Stigma can be a major stressor for people with schizophrenia and other mental illnesses, leading to emotional stress reactions and cognitive coping responses. Stigma is appraised as a stressor if perceived stigma-related harm exceeds an ind...
The relationship between the duration of untreated psychosis and outcome in low-and-middle income countries: a systematic review and meta analysis [0.03%]
低收入和中等收入国家未治疗精神病持续时间与临床结局之间关系的系统评价和meta分析
Saeed Farooq,Matthew Large,Olav Nielssen et al.
Saeed Farooq et al.
Background: The duration of untreated psychosis (DUP) is defined as the period between the onset of symptoms of psychosis and the start of antipsychotic treatment. Delay in the initiation of treatment, resulting in a long...
Henry A Nasrallah
Henry A Nasrallah
Juan Zhang,Jun Chen,Qi Xu et al.
Juan Zhang et al.
Presenilins are a group of proteins playing an important role in the Notch, ErbB4 and Wnt signaling pathways possibly associated with schizophrenia. The gene coding for presenilin 2 (PSEN2) is located on 1q42 and adjacent to a balanced tran...
Comparative Study
Schizophrenia research. 2009 Apr;109(1-3):121-9. DOI:10.1016/j.schres.2009.01.013 2009
Negative symptoms and concordant impairments in attention in schizophrenia: associations with social functioning, hope, self-esteem and internalized stigma [0.03%]
精神分裂症中的阴性症状和注意障碍：与社会功能、希望、自我评价及内化式标签的关联性研究
Paul H Lysaker,Jenifer L Vohs,Jack Tsai
Paul H Lysaker
Research has suggested that negative symptoms in schizophrenia may be closely linked to impairments in schizophrenia. Research on the strength and nature of this association has been equivocal, however. One possible explanation is that ther...