Ziprasidone vs clozapine in schizophrenia patients refractory to multiple antipsychotic treatments: the MOZART study [0.03%]
难治性精神分裂症患者抗精神病药疗效研究- Ziprasidone与Clozapine的对比（MOZART研究）
Emilio Sacchetti,Alessandro Galluzzo,Paolo Valsecchi et al.
Emilio Sacchetti et al.
This 18-week, randomized, flexible-dose, double-blind, double-dummy trial evaluated ziprasidone as an alternative to clozapine in treatment-refractory schizophrenia patients. Patients had a DSM-IV diagnosis of schizophrenia, a history of re...
Randomized Controlled Trial
Schizophrenia research. 2009 May;110(1-3):80-9. DOI:10.1016/j.schres.2009.02.017 2009
A stress-coping model of mental illness stigma: I. Predictors of cognitive stress appraisal [0.03%]
精神疾病污名化的压力应对模型：I.认知压力评估的预测因素
Nicolas Rüsch,Patrick W Corrigan,Abigail Wassel et al.
Nicolas Rüsch et al.
Stigma can be a major stressor for individuals with schizophrenia and other mental illnesses. It is unclear, however, why some stigmatized individuals appraise stigma as more stressful, while others feel they can cope with the potential har...
Weight gain, metabolic parameters, and the impact of race in aggressive inpatients randomized to double-blind clozapine, olanzapine or haloperidol [0.03%]
关于随机服用氯氮平、奥氮平或氟哌啶醇的急性住院精神病患者的增重情况及代谢参数变化和种族的影响研究
Menahem Krakowski,Pal Czobor,Leslie Citrome
Menahem Krakowski
Objective: The second-generation antipsychotic agents clozapine and olanzapine have been associated with weight gain and increased lipid and glucose blood levels. Since some of the neurotransmitters that are impaired in a...
Randomized Controlled Trial
Schizophrenia research. 2009 May;110(1-3):95-102. DOI:10.1016/j.schres.2009.02.006 2009
Risk/reward decision-making in schizophrenia: a preliminary examination of the influence of tobacco smoking and relationship to Wisconsin Card Sorting Task performance [0.03%]
精神分裂症中的风险收益决策：吸烟的影响及与威斯康星卡片分类测验成绩的关系的初步研究
Sarah W Yip,Kristi A Sacco,Tony P George et al.
Sarah W Yip et al.
Background: Individuals with schizophrenia show deficits in cognitive functioning, as evidenced by deficits on neurocognitive tasks such as the Wisconsin Card Sorting Task (WCST). Studies of risk/reward decision-making in...
Serotonergic dysfunction in the prodromal, first-episode and chronic course of schizophrenia as assessed by the loudness dependence of auditory evoked activity [0.03%]
利用声音诱发反应的振幅变化评估首发及慢性精神分裂症患者5-HT功能的异常
Yehonala Gudlowski,Seza Ozgürdal,Henning Witthaus et al.
Yehonala Gudlowski et al.
Recent studies revealing evidence of increased serotonergic neurotransmission in schizophrenia has generated substantial interest in the role of serotonin in its pathophysiology. None of these studies, however, have queried whether dysfunct...
Comparative Study
Schizophrenia research. 2009 Apr;109(1-3):141-7. DOI:10.1016/j.schres.2009.02.008 2009
Polymorphisms in SLC6A4, PAH, GABRB3, and MAOB and modification of psychotic disorder features [0.03%]
SLC6A4、PAH、GABRB3和MAOB的多态性与精神分裂症特征的关系
Sarah E Bergen,Ayman H Fanous,Dermot Walsh et al.
Sarah E Bergen et al.
We tested four genes [phenylalanine hydroxylase (PAH), the serotonin transporter (SLC6A4), monoamine oxidase B (MAOB), and the gamma-aminobutyric acid A receptor beta-3 subunit (GABRB3)] for their impact on five schizophrenia symptom factor...
H W Wiener,L Klei,M D Irvin et al.
H W Wiener et al.
While many studies have sought a window into the genetics of schizophrenia, few have focused on African-American families. An exception is the Project among African-Americans to Explore Risks for Schizophrenia (PAARTNERS), which seeks to id...
Comparative Study
Schizophrenia research. 2009 Apr;109(1-3):70-9. DOI:10.1016/j.schres.2009.02.007 2009
Functional polymorphism of the matrix metalloproteinase-9 (MMP-9) gene in schizophrenia [0.03%]
精神分裂症中基质金属蛋白酶-9(MMP-9)基因的功能多态性研究
Janusz K Rybakowski,Maria Skibinska,Pawel Kapelski et al.
Janusz K Rybakowski et al.
Matrix metalloproteinase-9 (MMP-9) plays a role in many pathological conditions (e.g. cancer and heart disease). Recently, MMP-9 has been implicated in the activity of the prefrontal cortex and we therefore hypothesized that the MMP-9 gene ...
Comparative Study
Schizophrenia research. 2009 Apr;109(1-3):90-3. DOI:10.1016/j.schres.2009.02.005 2009
A MicroRNA gene is hosted in an intron of a schizophrenia-susceptibility gene [0.03%]
一个精神分裂症易患基因的内含子中存在一个微小核糖核酸基因
Yanglong Zhu,Ted Kalbfleisch,Mark D Brennan et al.
Yanglong Zhu et al.
Schizophrenia (SZ) is a neuropsychiatric disorder that affects about 1% of the adult population. Numerous genes have been implicated in SZ susceptibility. MicroRNAs (miRNA) are small RNA molecules that regulate the translation of mRNAs via ...
Comparative Study
Schizophrenia research. 2009 Apr;109(1-3):86-9. DOI:10.1016/j.schres.2009.01.022 2009
White matter abnormalities in schizophrenia patients with tardive dyskinesia: a diffusion tensor image study [0.03%]
精神分裂症伴迟发性运动障碍患者的弥散张量成像研究
Ya Mei Bai,Kun-Hsien Chou,Ching-Po Lin et al.
Ya Mei Bai et al.
Objective: Tardive dyskinesia (TD) is a severe side effect of antipsychotics. While increasing evidence suggests that damaged brain microcircuitry of white matter (WM) is responsible for the clinical symptoms in schizophr...
Comparative Study
Schizophrenia research. 2009 Apr;109(1-3):167-81. DOI:10.1016/j.schres.2009.02.003 2009