A structured population modeling framework for quantifying and predicting gene expression noise in flow cytometry data [0.03%]
定量和预测流动式细胞仪数据分析中基因表达噪声的结构种群建模框架
Kevin B Flores
Kevin B Flores
We formulated a structured population model with distributed parameters to identify mechanisms that contribute to gene expression noise in time-dependent flow cytometry data. The model was validated using cell population-level gene expressi...
H T Banks,A Choi,T Huffman et al.
H T Banks et al.
We developed a series of models for the label decay in cell proliferation assays when the intracellular dye carboxyfluorescein succinimidyl ester (CFSE) is used as a staining agent. Data collected from two healthy patients were used to vali...
H T Banks,K L Rehm
H T Banks
We formulate an optimal design problem for the selection of best states to observe and optimal sampling times and locations for parameter estimation or inverse problems involving complex nonlinear nonlinear partial differential systems. An ...
J P Brooks,J H Dulá
J P Brooks
We formalize an algorithm for solving the L(1)-norm best-fit hyperplane problem derived using first principles and geometric insights about L(1) projection and L(1) regression. The procedure follows from a new proof of global optimality and...
H T Banks,Frédérique Charles,Marie Doumic Jauffret et al.
H T Banks et al.
We present a general class of cell population models that can be used to track the proliferation of cells which have been labeled with a fluorescent dye. The mathematical models employ fluorescence intensity as a structure variable to descr...
An improved bound on the Maximum Agreement Subtree problem [0.03%]
最大同感子树问题的改进上限Bounds on the maximum agreement subtree问题的研究
Mike Steel,László A Székely
Mike Steel
We improve the lower bound on the extremal version of the Maximum Agreement Subtree problem. Namely we prove that two binary trees on the same n leaves have subtrees with the same ≥ c log log n leaves which are homeomorphic, such that home...
E H Flach,S Schnell,J Norbury
E H Flach
There are two simple solutions to reaction-diffusion systems with limit-cycle reaction kinetics, producing oscillatory behaviour. The reaction parameter mu gives rise to a 'space-invariant' solution, and mu versus the ratio of the diffusion...