Clinical use of antacids [0.03%]
抗酸剂的临床应用
F Halter
F Halter
Antacids have for long been regarded as the mainstay of pharmacologic therapy in patients with dyspepsia. The advent of the histamine H2-antagonist and of proton pump inhibitors has provided simpler and overall more efficient therapeutic mo...
S J Konturek
S J Konturek
Most antacids contain magnesium and/or aluminium hydroxide but some include also bicarbonate and calcium carbonate. The net effect of antacid action is the reduction in gastric acidity and in peptic activity but recent studies indicate that...
A Berstad
A Berstad
Although patients with non-ulcer dyspepsia (NUD) and peptic ulcer disease present similar symptoms, the two diseases are pathophysiologically completely different and should be treated accordingly. The diagnosis of NUD is still based on neg...
A Gabryelewicz
A Gabryelewicz
The pathophysiological mechanisms of peptic ulcer and reflux oesophagitis are described. Special attention has been paid to the gastric mucosal defence factors, e.g. epidermal growth factor, mucosal blood flow and gastric mucus. The possibl...
Central histaminergic mechanisms in the corticosterone response to clonidine [0.03%]
克隆尼定的皮质酮反应中的中枢组胺机制
J Bugajski,A Gadek-Michalska,J Borycz et al.
J Bugajski et al.
Involvement of central histaminergic mechanisms in stimulation of the hypothalamic-pituitary-adrenal (HPA) axis by clonidine was investigated in conscious rats. Clonidine as well as adrenergic and histamine receptor antagonists were adminis...
Thyrotropin-releasing hormone (TRH) modulates vasopressin and oxytocin release from the hypothalamo-neurohypophysial system in dehydrated rats [0.03%]
下丘脑垂体后叶系统中催产素和血管加压素的释放受促甲状腺激素释放激素的调节
J Ciosek,J W Guzek,M Orłowska-Majdak
J Ciosek
Rats euhydrated and dehydrated during two or four days were given intracerebroventricularly (i.c.v.) thyrotropin-releasing hormone (TRH) in a daily dose of 200 ng dissolved in 10 microliters of 0.9% sodium chloride. A single dose of TRH inj...
Changes in the membrane potential can affect pepsinogen secretion of isolated rat chief cells [0.03%]
膜电位的变化影响大鼠主细胞的胃蛋白酶原分泌
W Zych,K Dołowy,J Ostrowski
W Zych
The aim of this study was to determine pepsinogen secretion by isolated rat chief cells in relation to changes of membrane potential obtained by the use of potassium ionophore valinomycin and different extracellular K+ concentrations, or pr...
The influence of calcium antagonists (verapamil, nifedipine, and MgCl2) on rat gastric damage induced by ethanol in vivo and in vitro [0.03%]
钙拮抗剂(维拉帕米、硝苯吡啶和MgCl2)对乙醇所致大鼠胃粘膜损伤的影响
J Ostrowski,J Pesta,D Linnik et al.
J Ostrowski et al.
Mucosal gastric injury was induced in vivo by oral administration of 75% ethanol to rats that were intraperitoneally pretreated with saline (controls), 4 mg/kg of verapamil, 0.4 mg/kg of nifedipine or 160 mg/kg of MgCl2. The glandular stoma...
Double-blind crossover study of ranitidine and ebrotidine in gastro-esophageal reflux disease [0.03%]
雷尼替丁与艾溴汀治疗胃食管反流病的双盲交叉临床研究
E Sito,P J Thor,M M[aczka et al.
E Sito et al.
Gastroesophageal reflux disease (GERD) is multifactorial disorder in which acid exposure has a central role in the mucosal damage, and the mainstay of medical treatment is the suppression of gastric acid secretion justifying the use of H2 r...
A comparison between the automatized impedance cardiography and pulsed-wave Doppler echocardiography methods for measurements of stroke volume (SV) and systolic time intervals (STI) [0.03%]
自动阻抗心电图与脉冲波多普勒超声心动图对.stroke volume(SV).和收缩期时间间隔(STI)测量的比较研究
G Cybulski,Z Miśkiewicz,J Szulc et al.
G Cybulski et al.
Stroke volume (SV) and systolic time intervals (STI) were measured automatically using impedance cardiography signals (ICG) and compared with those obtained by pulsed-wave Doppler echocardiography using the apex approach. The comparison was...