Protective influence of melatonin against acute esophageal lesions involves prostaglandins, nitric oxide and sensory nerves [0.03%]
褪黑素对急性食管损伤的保护作用涉及前列腺素、一氧化氮和感觉神经的影响
S J Konturek,O Zayachkivska,X O Havryluk et al.
S J Konturek et al.
Melatonin (MT) is known to protect gastrointestinal mucosa against various types of injury but its effects on esophageal damage have not been studied. We examined the effects of MT on acute esophageal injury and the mechanism involved in th...
Interactions between leptin and exendin-4, a glucagon-like peptide-1 agonist, in the regulation of food intake in the rat [0.03%]
脂蛋白与胰高血糖素样肽-1激动剂 Exendin-4在调节大鼠摄食方面的相互作用
E Bojanowska,A Nowak
E Bojanowska
Leptin interplays with other peptides to control feeding behaviour in humans and animals. Using exendin-4, an agonist of glucagon-like peptide-1, we investigated whether leptin modifies its effect on food intake in the rat. In the first ser...
Effect of subdiaphragmatic vagotomy and cholinergic agents in the hypothalamic-pituitary-adrenal axis activity [0.03%]
膈下迷走神经切断对下丘脑-垂体-肾上腺轴活动的影响及胆碱能药物的作用
A J Bugajski,D Zurowski,P Thor et al.
A J Bugajski et al.
In the present study, we examined whether the vagus nerve is involved in mediating the stimulation of hypothalamic-pituitary-adrenal (HPA) axis by cholinergic muscarinic and nicotinic agonists, carbachol and nicotine. The site of HPA axis m...
The relationship between constitutive ATP release and its extracellular metabolism in isolated rat kidney glomeruli [0.03%]
大鼠肾脏分离肾小球中基质ATP释放及其细胞外代谢之间的关系
J Karczewska,L Martyniec,G Dzierzko et al.
J Karczewska et al.
ATP and adenosine are important extracellular regulators of glomerular functions. In this study, ATP release from glomeruli suspension and its extracellular metabolism were investigated. Basal extraglomerular ATP concentration (1nM) increas...
Influence of ischemic preconditioning on blood coagulation, fibrinolytic activity and pancreatic repair in the course of caerulein-induced acute pancreatitis in rats [0.03%]
缺血预处理对急性胰腺炎大鼠血凝、纤维蛋白溶解活性及胰腺修复的影响
Z Warzecha,A Dembiński,P Ceranowicz et al.
Z Warzecha et al.
Previous studies have shown that ischemic preconditioning protects several organs, including the pancreas, from ischemia/reperfusion-induced injury. The aim of the investigation was to determine whether ischemic preconditioning affects the ...
Exposition of newborn rats to bacterial endotoxin impairs pancreatic enzyme secretion at adult age [0.03%]
新生鼠接触细菌内毒素可损害胰腺外分泌功能
J Jaworek,K Nawrot-Porabka,A Leja-Szpak et al.
J Jaworek et al.
Lipopolysaccharide (LPS, endotoxin) is the component of the cellular wall of Gram negative bacteria. Endotoxemia (sepsis) could produce multiorgan failure and in the early period of life LPS are responsible for the changes of metabolism and...
Polyviewed expression of the altered contractility of the guinea-pig ileum after ischemia in situ and superfusion in vitro [0.03%]
整体及分段肠条灌流法观察异丙肾上腺素致大鼠心肌缺血再灌注损伤后回肠收缩力的改变
J Santiago-Mejia,R Ventura-Martinez,C Gomez et al.
J Santiago-Mejia et al.
This study deals with the polyviewed expression of the altered contractility of the isolated ileum of the guinea-pig after ischemia/superfusion (I/S). Intestinal ischemia was produced by clamping the superior mesenteric artery for 40, 80 or...
Non-linear relationship between oxygen uptake and power output in the Astrand nomogram-old data revisited [0.03%]
奥strand图谱中摄氧量和功率输出之间的非线性关系-旧数据新见解
J A Zoladz,Z Szkutnik,J Majerczak et al.
J A Zoladz et al.
For the last decade there have been considerable discussion concerning the linearity / non-linearity of the oxygen uptake (V(O2)) - power output (W) relationship with strong experimental evidence of non-linearity provided mainly by breath-b...
E Nowakowska,K Kus,A Czubak et al.
E Nowakowska et al.
The experiments presented in this paper aimed to investigate the influence of atypical antiepileptic drug carbamazepine (CBZ, CAS 298-46-4) classified also as normothymic drug on spatial memory in Morris water maze test and anxiolytic effec...
The effect of an endogenous compound 1-methyl-1,2,3,4,-tetrahydroisoquinoline on morphine-induced analgesia, dependence and neurochemical changes in dopamine metabolism in rat brain structures [0.03%]
内源性化合物1-甲基四氢异喹啉对阿片类药物引起的痛觉异常、依赖以及大鼠脑部多巴胺代谢变化的影响研究
A Wasik,I Romańska,L Antkiewicz-Michaluk
A Wasik
1,2,3,4-Tetrahydroisoquinolines, among them the most interesting neuroprotective substance, an inhibitor of MAO, 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ), are endogenous compounds present in the central nervous system of mammals and...