[Novel central dopaminergic agents derived from atypical di-substituted 2-aminoindane-4, 7. Synthesis and central pharmacological profile] [0.03%]
一类新型双取代的2-氨基茚并四七三环吲哚烷衍生物中枢多巴胺药物的作用及合成研究
Rosa Elena Ferrer-Mavárez,Noribel Coromoto Urdaneta-Gutierrez,Nicole Porta-Knabenschuh et al.
Rosa Elena Ferrer-Mavárez et al.
In recent decades, many compounds with central dopaminergic activity have been designed, synthesized and evaluated pharmacologically. However, it has not been possible to obtain a drug able to improve or cure diseases involving dopaminergic...
[Effects of occupational exposure to pesticides on semen quality of workers in an agricultural community of Merida state, Venezuela] [0.03%]
委内瑞拉梅里达州农业社区的职业性农药暴露对工人精液质量的影响
Leticia Miranda-Contreras,Ibis Cruz,Jesús A Osuna et al.
Leticia Miranda-Contreras et al.
Numerous studies report adverse effects of pesticides on male reproductive health. The objectives of this study were to investigate whether there is a relationship between occupational exposure to pesticides and semen quality, and to determ...
[Serological diagnosis of sporotrichosis using an antigen of Sporothrix schenckii sensu stricto mycelium] [0.03%]
正规斯洛氏孢子丝菌菌丝抗原检验球孢子病的研究
Primavera Alvarado,Ana Ostos,Nohelys Franquiz et al.
Primavera Alvarado et al.
We developed and analyzed an Enzyme-Linked Immunosorbent Assay (ELISA) in order to detect antibodies in sera from sporotrichosis patients. We used a crude antigen of Sporothrix schenckii sensu stricto, obtained from the mycelial phase of th...
Ricardo Cárdenas Fernández
Ricardo Cárdenas Fernández
The gate control theory of pain, introduced by Melzack and Wall in 1965, led the way in pain research during the second half of the 20th century. Eventually, the observation of pain-related phenomena which the theory could not satisfactoril...
Editorial
Investigacion clinica. 2015 Jun;56(2):109-10. DOI: 2015
Raibel Suárez,Neudo Buelvas
Raibel Suárez
Inflammation is a rapid biologic response of the immune system in vascular tissues, directed to eliminate stimuli capable of causing damage and begin the process of repair. The macromolecular complexes known as "inflammasomes" are formed by...
Cystic fibrosis and pregnancy: counseling, obstetrical management and perinatal outcome [0.03%]
囊性纤维化与妊娠：咨询、产科管理和围产期结局
Charalampos Grigoriadis,Aliki Tympa,Kassiani Theodoraki
Charalampos Grigoriadis
The progress in research of in vitro fertilization and fetal-maternal medicine allows more women and men, with fertility problems due to cystic fibrosis, to have a baby. In the majority of cases, pregnancy in women with cystic fibrosis resu...
Syringoma of vulva: an unusual presentation. Clinical, morphological and immunohistochemical aspects [0.03%]
阴道的棘皮症：一个不寻常的表现。临床，形态和免疫组化特征
José Núñez-Troconis,María Elena Viloria de Alvarado
José Núñez-Troconis
The case of a 34-year-old woman, who consulted because she observed the appearance of numerous yellow-white asymptomatic papules on the vulva, is presented. Clinical diagnosis of syringoma of vulva was established. The pathological and immu...
Case Reports
Investigacion clinica. 2015 Mar;56(1):60-5. DOI: 2015
P16(INK 4a) and Ki-67 expression in human papilloma virus-related head and neck mucosal lesions [0.03%]
人乳头瘤病毒相关性头颈部粘膜病变中P16（INK 4a）和Ki-67的表达
Sibel Elif Gültekin,Burcu Sengüven,Jens Peter Klussmann et al.
Sibel Elif Gültekin et al.
Human papilloma virus (HPV) is postulated as a risk factor in the etiology of some specific mucosal pathologies in the head and neck regions. Despite the frequent use of p16(INK4a) as a surrogate marker for HPV-infection, there is still con...
Jaqueline Villar,Héctor J Finol,Sonia H Torres et al.
Jaqueline Villar et al.
Hashimoto thyroiditis (HT) is an autoimmune disease of the thyroid gland. Patients may present or not a hypothyroid state, and frequently have manifestations of myopathy. The present work was aimed to assess the clinical symptoms and signs ...
[Prone position: effect on gas exchange and functional capacity for exercise in patients with pulmonary hypertension] [0.03%]
俯卧位：对肺动脉高压患者气体交换和运动功能耐受的影响
Andrea Carolina Bastidas-L,José A Colina-Chourio,Jesnel M Guevara et al.
Andrea Carolina Bastidas-L et al.
The objective of this investigation was to evaluate gas exchange and cardiopulmonary functional behavior in patients with pulmonary hypertension (PH) before, during and after the change to a prone position. Thirty patients with PH and alter...