[Mutations in the GATA4 gen in patients with non-syndromic congenital heart disease] [0.03%]
非综合征性先天性心脏病患者的GATA4基因突变研究
Diana Carolina Orjuela Quintero,Federico Núñez,Víctor Caicedo et al.
Diana Carolina Orjuela Quintero et al.
Congenital heart diseases are defined as any heart or large vessel structural abnormality resulting from abnormal embryonic development, usually described between the 3rd and 10th week of gestation. They comprise the second cause of death i...
[Is the fight against dengue complicated with the emergence of a new viral serotype?] [0.03%]
登革新血清型的出现是否使登革热防控更复杂了？
Nereida Valero,Yasmir Quiroz
Nereida Valero
Dengue is a viral acute febrile illness, currently considered one of the most important arbovirosis worldwide in terms of morbidity, mortality and economic impact. Various theories have been proposed to explain the pathogenesis of severe fo...
Editorial
Investigacion clinica. 2014 Sep;55(3):203-5. DOI: 2014
[Pharmacogenomics of the first-line treatment for gastric cancer: advances in the identification of genomic biomarkers for clinical response to chemotherapy] [0.03%]
一线胃癌治疗的药物基因组学：寻找化疗临床疗效的基因生物标志物的研究进展
Carlos Castro-Rojas,Rocío Ortiz-Lópezj,Augusto Rojas-Martínez
Carlos Castro-Rojas
Gastric cancer (GC) is often diagnosed at later stages due to the lack of specificity of symptoms associated with the neoplasm, causing high mortality rates worldwide. The first line of adjuvant and neoadjuvant treatment includes cytotoxic ...
Diego Higuera,Martha Bravo,Belsy Guerrero
Diego Higuera
Sickle cell syndrome (SCS) includes a group of congenital hemolytic anemias associated to the presence of hemoglobin S, which is characterized by acute pain episodes and progressive damage of different organs. Some patients with sickle cell...
[Exstrophy of rectal duplication associated with anorectal malformation and penoscrotal transposition with perineal hypospadias. A case report] [0.03%]
会阴尿道下裂伴直肠畸形及阴茎隐睾征的病例报告
Jesús Angel Fernández Fernández,Luis Parodi Hueck,Joanna Carrasco Fermín
Jesús Angel Fernández Fernández
We present the case of a male patient who required treaatment due to anorectal agenesis with recto urethral fistula and penoscrotal transposition with perineal hypospadias, associated with a perineal tumor. The perineal tumor was found stro...
Case Reports
Investigacion clinica. 2014 Jun;55(2):168-72. DOI: 2014
[Selection of heparin-sensitive dengue virus variants in BHK-21 cells] [0.03%]
用于伪病毒感染BHK-21细胞中敏感型登革病毒变异株的筛选
Argelia Celis,Zoila Moros,Marlene Gerder et al.
Argelia Celis et al.
Several studies have shown that adaptation of various viruses to grow in certain cell lines of vertebrates, leads to the selection of virus variants that bind heparan sulfate (HS) with high affinity. In this study we investigated the suscep...
In vitro assessment of commercial sunscreens available in Latin America [0.03%]
拉美市场上防晒产品中UV过滤剂的体外评估研究
Juan Pablo Castanedo-Cázares,Karla Martínez-Rosales,Diana Hernández-Blanco et al.
Juan Pablo Castanedo-Cázares et al.
In Latin America, people have largely abandoned the practice of wearing hats and traditional clothing that provided skin protection. Sunscreen application has therefore become essential to protect against the increased sun exposure. The phy...
[Lack of association between the S447X variant of the lipoprotein lipase gene and plasma lipids. A preliminary study] [0.03%]
[载脂蛋白LPL基因S447X变异与血浆脂质缺乏关联性初步研究]
Mariana Zambrano Morales,Erika Fernández Salgado,Ligia Balzán Urdaneta et al.
Mariana Zambrano Morales et al.
The increase in lipid plasma values is an important cardiovascular risk factor. Lipoprotein lipase (LPL) plays an important role in the lipoprotein metabolism and metabolic and genetic factors may influence its levels and functions. The S44...
[Risk factors associated with the diagnosis of chronic Chagasic miocardiopathy in seropositive individuals from Barinas state, Venezuela] [0.03%]
[委内瑞拉巴里纳斯州查.gca阳性个体慢性心脏病诊断的相关危险因素]
Beatriz González,Martha Silva,Yusra Al-Atrache et al.
Beatriz González et al.
This study evaluates the risk factors associated with the diagnosis of chronic chagasic miocardiopathy (CChM) in 115 seropositive individuals to anti-Trypanosoma cruzi antibodies, in Barinas state, Venezuela. Serology was performed with ELI...
Janice Fernández-D&#x;Pool,Robby Jameson,Angel Brito
Janice Fernández-D&#x;Pool
The objective of this investigation was to analyze the prevalence of musculoskeletal pain (MSP) in oil tanker crew members in Venezuela. A descriptive cross-sectional study was implemented, using a modified version of the Standardized Nordi...