[Advance in the study of myocardial ischemic preconditioning and postconditioning and the clinical applications] [0.03%]
心肌缺血预适应和后适应的研究进展及临床应用前景
Yu-Jie Wu,Lian-Hua Fang,Guan-Hua Du
Yu-Jie Wu
Myocardial ischemic preconditioning and postconditioning can reduce myocardial infarct size, improve myocardial contractility, protect coronary endothelial and myocardial cell ultrastructure, as well as reduce the incidence of arrhythmias. ...
Jian Zhou,Bao-Feng Ge,Ke-Ming Chen et al.
Jian Zhou et al.
This study is to investigate effects of genistein on rat femoral bone metabolic in vitro. Rat femoral tissues was isolated and randomly divided into two groups including control group and genistein (1 x 10(-5) mol x(-1)) group. Determinatio...
[Cloning and expression analysis of HMG-CoA reductase from Aquilaria sinensis (Lour.) Gilg] [0.03%]
沉香[H MG-CoA还原酶的克隆与表达分析]
Yan-Hong Xu,Xin Yang,Zheng Zhang et al.
Yan-Hong Xu et al.
3-Hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR) is the first rate-limiting enzyme for sesquiterpene synthesis in the mevalonate (MVA) pathway. The specific primers were designed according to the transcript sequence of AsHMGR2 from th...
[Molecular cloning and characterization of S-adenosyl-L-methionine decarboxylase gene (DoSAMDC1) in Dendrobium officinale] [0.03%]
铁皮石斛S-腺苷甲硫氨酸脱羧酶基因(DoSAMDC1)的克隆及表达分析
Ming-Ming Zhao,Gang Zhang,Da-Wei Zhang et al.
Ming-Ming Zhao et al.
S-Adenosyl-L-methionine decarboxylase (SAMDC) is a key enzyme in the polyamines biosynthesis, thus is essential for basic physiological and biochemical processes in plant. In the present study, a full length cDNA of DoSAMDC1 gene was obtain...
[Pharmacokinetics and tissue distribution of irinotecan hydrochloride nanoparticles] [0.03%]
盐酸伊立替康纳米粒的药动学及组织分布研究
Fu-Ying Yang,Wen-Ping Zhang,He-Li Chen et al.
Fu-Ying Yang et al.
To investigate the pharmacokinetics of irinotecan hydrochloride (CPT-11) in rats and the tissue distribution of CPT-11 in mice after injection of irinotecan hydrochloride nanoparticles (CPT-11 NPs) via tail veins, separately, a LC-MS/MS met...
[In vitro transdermal delivery of the active fraction of xiangfusiwu decoction based on principal component analysis] [0.03%]
基于主成分分析的香附四物汤活性部位体外透皮递送研究
Zhen-Hao Li,Pei Liu,Da-Wei Qian et al.
Zhen-Hao Li et al.
The objective of the present study was to establish a method based on principal component analysis (PCA) for the study of transdermal delivery of multiple components in Chinese medicine, and to choose the best penetration enhancers for the ...
[The influence of spray drying process conditions on physical, chemical properties and lung inhaling performance of Panax notoginseng saponins - tanshinone II A composite particles] [0.03%]
喷干工艺条件对三七皂苷-丹参酮ⅡA复合粒子的物理、化学性质及肺部吸入性能的影响
Hua-Mei Wang,Ting-Ming Fu,Li-Wei Guo
Hua-Mei Wang
This study is to report the influence of conditions in spray drying process on physical and chemical properties and lung inhaling performance of Panax notoginseng Saponins - Tanshinone II A composite particles. According to the physical and...
[LC-MS quantification and pharmacokinetics of the multi-constituents of Huangqin Tang in rat plasma after different single oral doses] [0.03%]
不同剂量一次性给药后黄芩汤多成分在大鼠血浆中的LC-MS定量及其药代动力学研究
Tao Li,Yi-Wei Wang,Yan-Li Wang et al.
Tao Li et al.
The current study aims to investigate the pharmacokinetic properties of Huangqin Tang on different oral doses. An LC-MS method for simultaneous determination of flavonoids and terpenoids in rat plasma was developed and validated. Plasma sam...
Structure elucidation of degradation products of Z-ligustilide by UPLC-QTOF-MS and NMR spectroscopy [0.03%]
采用UPLC-QTOF-MS和NMR光谱法阐明Z-当归内酯的降解途径及其杂质结构
Ai-Hua Zuo,Meng-Chun Cheng,Rong-Jie Zhuo et al.
Ai-Hua Zuo et al.
Z-Ligustilide, a major phthalide isolated from a widely used traditional Chinese medicine Ligusticum chuanxiong, possesses various pharmacological activities including neuroprotective, anti-inflammatory, antiproliferative and vasorelaxing e...
[Effects of ligustrazine on extracellular dopamine levels in rat brain dialysate] [0.03%]
三七药效部位对脑内多巴胺影响的研究
Yun-Feng Lü
Yun-Feng Lü
Using brain microdialysis and LC-ECD, the content of dopamine in rat brain was detected to investigate the effects of ligustrazine. A liquid chromatography-electrochemical detector method has been established and validated for the determina...