[Identification of Salvia shandongensis new species based on sequences of the plastid psbA-trnH intergenic region] [0.03%]
基于叶绿体psbA-trnH间区序列的山东鼠尾草新种识别研究
Xiao-Juan Li,Jian-Ping Han,Jian-Xiu Li et al.
Xiao-Juan Li et al.
To identify Salvia shandongensis and its relatives at molecular level, the psbA-trnH intergenic region of three species including Salvia shandongensis, Salvia miltiorrhiza and S. miltiorrhiza f. alba were amplified and sequenced. Sequences ...
[Self-assembly and in vitro and in vivo evaluation of spherical crystallized interferon for sustained delivery] [0.03%]
[self assembly and in vitro and in vivo evaluation of spherical crystallized interferon for sustained delivery]干扰素球形结晶的自组装及其体内外评价
Kai Shi,Fu-De Cui,Hong-Shu Bi et al.
Kai Shi et al.
It is a challenging and important project to prolong the in vivo half life of protein and peptide drugs by physicochemical methods without new molecular entities generation. Protein crystallization provides a new strategy for improving the ...
[The effects and its mechanism of N-arginine chitosan as transdermal enhancer] [0.03%]
N-乙酰壳聚糖经皮给药促进作用及其机制研究
Feng-Yi Cheng,Zhen-Hai Zhang,Jian-Ping Zhou et al.
Feng-Yi Cheng et al.
The purpose of this study is to investigate the penetration effects and mechanism of N-arginine chitosan (ACS). This novel transdermal enhancer with a mimetic structure of cell-penetration peptides was synthesized by introducing hydrophilic...
[Applicability of a natural swelling matrix as the propellant of osmotic pump tablets] [0.03%]
[天然胀大基质作为渗透泵片推进剂的应用]
Li Wu,Hai-Yan Li,Xian-Zhen Yin et al.
Li Wu et al.
The purpose of this study is to investigate the applicability of a natural swelling matrix derived from boat-fruited sterculia seed (SMS) as the propellant of osmotic pump tablets. The sugar components, static swelling, water uptake and vis...
Fei Li,Shuang-Shuang Song,Yun Liu et al.
Fei Li et al.
To increase the dissolution rate and extent of valsartan, valsartan nanosuspensions have been prepared. Controlled precipitation assisted with sonication is utilized to prepare valsartan nanosuspensions, the concentration of the drug, stabi...
[Pharmacodynamics and pharmacokinetics of batroxobin in Beagle dog] [0.03%]
巴西矛头蛇毒凝血酶在比格犬体内的药动学及药效学研究
Zi-Hua Zheng,Xiao-Xia Zhu,Hui Gan et al.
Zi-Hua Zheng et al.
Healthy Beagle dogs were administrated with batroxobin by intravenous infusion at high, medium and low doses. The study of pharmacodynamics and pharmacokinetics was intended to clarify the relevance of them and provided strong evidence for ...
[Metabolomic study of the action mechanism of nourishing blood effect of fo-shou-san on blood deficiency mice] [0.03%]
补血方 Fors支柱血虚小鼠的代谢组学作用机制研究
Wei-Xia Li,Mei-Yan Huang,Yu-Ping Tang et al.
Wei-Xia Li et al.
The metabolic effect of Fo-Shou-San on blood deficiency mice was studied by using metabolomic method. UPLC-QTOF/MS was used to analyze the plasma metabolome in blood deficiency mice. MS data were processed by MarkerLynx software. With multi...
Long-Hai Jian,Xiu-Hong Mao,Ke Wang et al.
Long-Hai Jian et al.
A method of LC-QTOF/MS combining with chemical synthesis has been used to determine the structures of three novel bile acids from bear bile powder. Reference substances of tauroursodeoxycholic acid and taurochenodeoxycholic acid were oxidiz...
[Analysis and identification of degradation products of buagafuran by high performance liquid chromatography-diode array detection-tandem mass spectrometry] [0.03%]
高效液相色谱-二极管阵列检测器-串联质谱法定量分析布桂芬碱降解产物
Xue-Jun Xia,Jiu-Ming He,Chun Li et al.
Xue-Jun Xia et al.
An HPLC-DAD-MS/MS method was developed for rapid analysis and identification of degradation products of buagafuran. Buagafuran and degradation products were separated on a Zorbax C8 column (5 microm, 4.6 mm x 150 mm) using acetonitrile-wate...
[Simultaneous separation and detection of principal component isomer and related substances of raw material drug of ammonium glycyrrhizinate by RP-HPLC and structure confirmation] [0.03%]
高效液相色谱法同时分离和检测甘草酸铵原料药主成分异构体及相关物质及结构确证
Yan-Yan Zhao,Li-Yan Liu,Yuan-Yuan Han et al.
Yan-Yan Zhao et al.
A simple, fast and sensitive analytical method for the simultaneous separation and detection of 18alpha-glycyrrhizinic acid, 18beta-glycyrrhizinic acid, related substance A and related substance B by RP-HPLC and drug quality standard was es...