Hui-hui Chen,Gui-kai Liang,Zhang-ting Yao et al.
Hui-hui Chen et al.
As extremely important inflammatory cells in the tumor microenvironment, tumor-associated macrophages (TAMs) can secrete a variety of chemokines and cytokines, which play an important role in the occurrence of tumor growth and metastasis. R...
Wen Liu,Wen-jie Guo,Qiang Xu et al.
Wen Liu et al.
Activation of inflammasomes involves multi-protein assembly and activation of inflammatory caspase and maturation of pro-inflammatory cytokines interleukin-1β(IL-1β) and interleukin-18(IL-18). Among those types of inflammasomes, NOD (nucl...
[Cloning and expression analysis of 1-deoxy-D-xylulose-5-phosphate reductoisomerase gene (CcDXR1) in Cinnamomum camphora L.) Presl] [0.03%]
樟树CcDXR1基因的克隆及表达分析
Han Zheng,Li Jing,Na Yao et al.
Han Zheng et al.
1-Deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) is the second rate-limiting enzyme of terpenoid biosynthesis in the methylerythritol-4-phosphate pathway. According to the transcriptome database of Cinnamomum camphora, the DXR cDNA was...
[Analysis of global ecology of Panax notoginseng in suitability and quality] [0.03%]
适生性与质量特征角度的三七全球生态地理学分析
Xiang-xiao Meng,Lin-fang Huang,Lin-lin Dong et al.
Xiang-xiao Meng et al.
In this study, the Geographic Information System for Global Medicinal Plants(GMPGIS) was used to assess the global production and ecological adaptation of Panax notoginseng. Based on climate factors and soil types of P. notoginseng from 326...
[Preparation and evaluation of pharmacodynamic of the pectin-doxorubicin conjugate nanosuspensions] [0.03%]
[pH敏感性果胶-阿霉素偶联物纳米混悬液的制备及其药效学评价]
Fei Fan,Xiao-hai Tang,Xia Li et al.
Fei Fan et al.
This study was conducted to produce pectin-doxorubicin conjugate（PDC） nanosuspensions by high-pressure homogenization, and investigating the physico-chemical properties, the cumulative release rate in vitro and in vivo, and the anti-tumor act...
Yu Huang,Xian-cheng Zhan,Fang-jun Lü
Yu Huang
Measurement of drug solubility is one of the key elements of compound characterization during the drug discovery and development process. A broad variety of solubility assay methods have been developed, including equilibrium method which re...
[Response surface analysis for the optimization of extraction condition for polysaccharides from Epimedium polysaccharides and studies on its tumor immune activities] [0.03%]
基于Epimedium Polysaccharide响应面分析法优化提取工艺及其抗肿瘤免疫作用研究
Cheng-cheng Wang,Jia-yan Su,Ji-yan Cai et al.
Cheng-cheng Wang et al.
To enhance the efficiency of the extraction for Epimedium koreanum Nakai polysaccharides, we conducted the Box-Benhnken experiment and examined the response surface. C57 BL6 mice were used as Lewis-bearing mice model in the study of the pol...
[Serum pharmacochemistry of honey-fried Stemona tuberosa Lour. by UHPLC-QTOF/MS and MetaboLynx analysis] [0.03%]
基于UHPLC-QTOF/MS及MetaboLynx分析的蜜玄参的血清药化研究
Wei Dong,Xiu-jie Hao,Chao-zhong Wang et al.
Wei Dong et al.
A high throughput UHPLC-QTOF/MS method was established to analyze and identify the constituents in rat plasma after oral administration of honey-fried Stemona tuberosa Lour. extract. Automated data analysis software MetaboLynx was developed...
[Rapid analysis of glycerophospholipids in RAW264.7 macrophage with UHPLC-QTOF/MS] [0.03%]
[采用UHPLC-QTOF/MS快速分析RAW264.7巨噬细胞中的甘油磷脂]
Yu-qi She,Xue-rong Xiao,Xia Wu et al.
Yu-qi She et al.
An ultra performance liquid chromatography tandem quadrupole time-of-flight mass spectrometric method was developed for rapid analysis of glycerophospholipids in RAW264.7 macrophage. The modified Bligh-Dyer was applied to extract glyceropho...
[Rapid identification of the different constituents in Fructus Schisandrae Chinensis before and after processing by UHPLC-QTOF/MS~E combining with metabonomics] [0.03%]
基于UHPLC-QTOF/MS~E结合代谢组学的五味子药材及其炮制品中化学成分快速识别方法研究
Wei Li,Yong-gui Song,Kuang-yi Liu et al.
Wei Li et al.
This study was performed to use UHPLC-QTOF/MSE technology to rapidly search and identify variations of chemical ingredients between Fructus Schisandrae Chinensis and its processed products. The present study provides a basis for the study o...