Heike Lange,Dominique Gagliardi
Heike Lange
The exosome is a large protein complex mediating 3'-5' RNA degradation in both nucleus and cytosol of all eukaryotic cells. It consists of nine conserved subunits forming the core complex, which associates with ribonucleolytic enzymes and o...
Michal Lubas,Aleksander Chlebowski,Andrzej Dziembowski et al.
Michal Lubas et al.
Discovery of the evolutionary conserved RNA exosome was a milestone in RNA biology. First identified as an activity essential for the processing of ribosomal RNA, the exosome has since proved to be central for RNA processing and degradation...
Chung S Yang,Hong Wang,Jayson X Chen et al.
Chung S Yang et al.
The inhibitory activities of tea catechins against carcinogenesis and cancer cell growth have been demonstrated in a large number of laboratory studies. Many mechanisms for modulating cancer signaling and metabolic pathways have been propos...
Molecular Targets of Honokiol: A Promising Phytochemical for Effective Cancer Management [0.03%]
汉酮分子靶点：一种有前景的植物化学成分，可有效管理癌症
Courey Averett,Sumit Arora,Haseeb Zubair et al.
Courey Averett et al.
Honokiol is a bioactive, biphenolic phytochemical, present in the aerial parts of plants classified under the genus Magnolia. It has been an important constituent of Asian traditional medicine and is used against many ailments. Honokiol pos...
Adeeb Shehzad,Raheem Shahzad,Young Sup Lee
Adeeb Shehzad
Curcumin (diferuloylmethane) is the biphenolic active compound of turmeric. Curcumin has been used for hundreds of years to treat various ailments. Curcumin has been reported to exert numerous pharmacological effects by modulating multiple ...
Neem Limonoids as Anticancer Agents: Modulation of Cancer Hallmarks and Oncogenic Signaling [0.03%]
Neem苦味素作为抗癌剂：癌症标志和致癌信号转导的调控
Siddavaram Nagini
Siddavaram Nagini
Neem (Azadirachta indica A. Juss) is one of the most versatile medicinal plants, widely distributed in the Indian subcontinent. Neem is a rich source of limonoids that are endowed with potent medicinal properties predominantly antioxidant, ...
Research Progress on Natural Triterpenoid Saponins in the Chemoprevention and Chemotherapy of Cancer [0.03%]
天然三萜皂苷抗肿瘤研究进展
Jun-Rong Du,Fang-Yi Long,Chu Chen
Jun-Rong Du
Triterpenoid saponins are glycosides with remarkable structural and bioactive diversity. They are becoming increasingly significant in the treatment of cancer due to their efficacy and safety. This chapter provides an update on the sources,...
Yoichi Matsuo,Hiromitsu Takeyama
Yoichi Matsuo
Natural products have been regarded as safe and have been shown to have anticancer activities against a variety of cancer cell types. Zerumbone was initially isolated from the rhizome of a subtropical wild shampoo ginger (Zingiber zerumbet ...
S Zahra Bathaie,Azam Bolhassani,Fuyuhiko Tamanoi
S Zahra Bathaie
Saffron carotenoids, crocin and crocetin, have shown anticancer activity in various animal models of cancer and against different cancerous cell lines. The radical scavenging property and activation of antioxidant defense system are two wel...
Chin-Lin Hsu,Gow-Chin Yen
Chin-Lin Hsu
Ganoderma species is known as a functional mushroom used in many Asian countries. Triterpenoids, ganoderic acids, and lucidenic acids have been isolated from Ganoderma species (Ganodermataceae family), such as Ganoderma lucidum. Triterpenoi...