Fumio Otsuka
Fumio Otsuka
New biological activities of bone morphogenetic proteins (BMPs) in the endocrine system have recently been revealed. The BMP system is composed of approximately 30 ligands and preferential combinations of type I and type II receptors. The B...
Histological analysis of failed cartilage repair after marrow stimulation for the treatment of large cartilage defect in medial compartmental osteoarthritis of the knee [0.03%]
膝关节内侧间室骨关节炎大范围软骨缺损采用刺激骨髓治疗失败后的组织学分析
Kenichiro Sakata,Takayuki Furumatsu,Nobuhiro Abe et al.
Kenichiro Sakata et al.
Bone marrow-stimulating techniques such as microfracture and subchondral drilling are valuable treatments for full-thickness cartilage defects. However, marrow stimulation-derived reparative tissues are not histologically well-documented in...
Case Reports
Acta medica Okayama. 2013;67(1):65-74. DOI:10.18926/AMO/49259 2013
Papillary thyroid carcinoma arising from a median ectopic thyroid with no thyroglossal duct remnant [0.03%]
无舌骨甲状窦遗迹的中线异位甲状腺乳头状癌的发生发展
Tomoyasu Tachibana,Yorihisa Orita,Masayoshi Fujisawa et al.
Tomoyasu Tachibana et al.
Thyroid carcinomas arising from ectopic thyroid tissue are uncommon;most of them arise from thyroid tissue in thyroglossal cysts. A rare case of a 66-year-old woman with papillary thyroid carcinoma arising from median ectopic thyroid tissue...
Case Reports
Acta medica Okayama. 2013;67(1):61-4. DOI:10.18926/AMO/49258 2013
Severe gummy smile with class II malocclusion treated with LeFort I osteotomy combined with horseshoe osteotomy and intraoral vertical ramus osteotomy [0.03%]
重度笑龈笑伴安氏II类错牙合的改良下颌支垂直劈开截骨与Le Fort I截骨联合矫治术治疗报告
Tsuyoshi Shimo,Akiyoshi Nishiyama,Tokiari Jinno et al.
Tsuyoshi Shimo et al.
In this article, we report the successful surgical treatment of a patient, 34 years of age, who had a severe gummy smile and a class II malocclusion. The patient had an 11-mm gingival exposure during full smile and a convex profile. A LeFor...
Case Reports
Acta medica Okayama. 2013;67(1):55-60. DOI:10.18926/AMO/49257 2013
A prospective study of long-term outcomes in female patients with nonalcoholic steatohepatitis using age- and body mass index-matched cohorts [0.03%]
基于年龄和BMI匹配队列的非酒精性脂肪肝病女性患者的长期预后研究
Hiroaki Hashizume,Ken Sato,Yuichi Yamazaki et al.
Hiroaki Hashizume et al.
In patients with nonalcoholic steatohepatitis (NASH), the prevalence of cirrhosis is higher among women than men, and hepatocellular carcinoma (HCC) develops mainly in the cirrhotic stage among women. However, the long-term outcomes in fema...
Multiple regression analysis for grading and prognosis of cubital tunnel syndrome: assessment of Akahori's classification [0.03%]
用于尺神经卡压分级和预后的多元回归分析：对Akahori分型的评价研究
Masutaka Watanabe,Seizaburo Arita,Hiroyuki Hashizume et al.
Masutaka Watanabe et al.
The purpose of this study was to quantitatively evaluate Akahori's preoperative classification of cubital tunnel syndrome. We analyzed the results for 57 elbows that were treated by a simple decompression procedure from 1997 to 2004. The re...
Case Reports
Acta medica Okayama. 2013;67(1):35-44. DOI:10.18926/AMO/49255 2013
Shift work and diabetes mellitus among male workers in Japan: does the intensity of shift work matter? [0.03%]
日本男工中的轮班工作与糖尿病：轮班的强度有关吗？
Katsuhiko Ika,Etsuji Suzuki,Toshiharu Mitsuhashi et al.
Katsuhiko Ika et al.
The purpose of this study was to examine the association between shift work and diabetes mellitus by separating shift workers according to the intensity of their shift work (seasonal shift work and continuous shift work). Between May and Oc...
Silenced expression of NFKBIA in lung adenocarcinoma patients with a never-smoking history [0.03%]
无吸烟史肺腺癌患者中NFKBIA低表达及其临床意义
Masashi Furukawa,Junichi Soh,Hiromasa Yamamoto et al.
Masashi Furukawa et al.
Nuclear factor of κ-light polypeptide gene enhancer in B cells inhibitor α (NFKBIA), which is a tumor suppressor gene, was found to be silenced in lung adenocarcinomas. We examined NFKBIA expression, mutations in the EGFR and K-ras genes,...
Phospholipase C produced by Clostridium botulinum types C and D: comparison of gene, enzymatic, and biological activities with those of Clostridium perfringens alpha-toxin [0.03%]
肉毒杆菌C和D型磷脂酶C：与破伤风毒素α毒素基因、酶促及生物活性的比较研究
Ni Nengah Dwi Fatmawati,Yoshihiko Sakaguchi,Tomonori Suzuki et al.
Ni Nengah Dwi Fatmawati et al.
Clostridium botulinum type C and D strains recently have been found to produce PLC on egg yolk agar plates. To characterize the gene, enzymatic and biological activities of C. botulinum PLCs (Cb-PLCs), the cb-plc genes from 8 strains were s...
Comparative Study
Acta medica Okayama. 2013;67(1):9-18. DOI:10.18926/AMO/49252 2013
Chronic graft-versus-host disease: disease biology and novel therapeutic strategies [0.03%]
慢性移植物抗宿主病：疾病生物学及新的治疗策略
Hisakazu Nishimori,Yoshinobu Maeda,Mitsune Tanimoto
Hisakazu Nishimori
Graft-versus-host disease (GVHD) is a major complication after allogeneic hematopoietic stem cell transplantation. Chronic GVHD often presents with clinical manifestations that resemble those observed in autoimmune diseases. Standard treatm...