Promising Effectiveness of Combined Chemotherapy and Immunotherapy in Patients with Advanced Non-small Cell Lung Cancer: A Real-World Prospective Observational Study (CS-Lung-003) [0.03%]
晚期肺腺癌综合化疗免疫治疗疗效的全国多中心真实世界研究（CS-LUNG-003）
Nobuhiro Kanaji,Kazuya Nishii,Yukari Tsubata et al.
Nobuhiro Kanaji et al.
This prospective observational study investigated the clinical status of patients with advanced non-small cell lung cancer (NSCLC) treated with cytotoxic chemotherapy+an immune checkpoint inhibitor (chemo + IO) as first-line treatment in a ...
Observational Study
Acta medica Okayama. 2025 Jun;79(3):167-176. DOI:10.18926/AMO/68724 2025
Continuous Stimulation with Glycolaldehyde-derived Advanced Glycation End Product Reduces Aggrecan and COL2A1 Production via RAGE in Human OUMS-27 Chondrosarcoma Cells [0.03%]
甘油醛衍生的糖基化终末产物持续刺激通过RAGE减少人OUMS-27软骨肉瘤细胞中的aggrecan和COL2A1生成
Omer Faruk Hatipoglu,Takashi Nishinaka,Kursat Oguz Yaykasli et al.
Omer Faruk Hatipoglu et al.
Chondrocytes are responsible for the production of extracellular matrix (ECM) components such as collagen type II alpha-1 (COL2A1) and aggrecan, which are loosely distributed in articular cartilage. Chondrocyte dysfunction has been implicat...
Immunometabolic Regulation of Innate Immunity in Systemic Lupus Erythematosus [0.03%]
系统性红斑狼疮中固有免疫的免疫代谢调节作用
Haruki Watanabe,Yoshinori Matsumoto,Jun Wada
Haruki Watanabe
Pathogens or their components can induce long-lasting changes in the behavior of innate immune cells, a process analogous to "training" for future threats or environmental adaptation. However, such training can sometimes have unintended con...
Safe Resection of Esophageal Cancer with a Non-Recurrent Inferior Laryngeal Nerve Associated with an Aberrant Right Subclavian Artery Using Intraoperative Nerve Monitoring [0.03%]
术中神经监测下行迷走右锁骨下动脉伴非再发性喉返神经食管癌安全切除术
Yasushige Takeda,Kazuhiro Noma,Naoaki Maeda et al.
Yasushige Takeda et al.
In thoracic esophageal cancer, lymph node dissection around the recurrent laryngeal nerve is crucial but poses a risk of nerve palsy, affecting postoperative quality of life. In cases with an aberrant right subclavian artery (ARSA), the rig...
Case Reports
Acta medica Okayama. 2025 Apr;79(2):139-144. DOI:10.18926/AMO/68654 2025
Calcified Amorphous Tumor of the Left Ventricle with Paroxysmal Atrial Fibrillation [0.03%]
左心室内钙化无定形肿瘤伴阵发性房颤
Yasufumi Fujita,Shuji Shimizu,Makoto Mohri
Yasufumi Fujita
Cardiac calcified amorphous tumor (CAT) is a rare, benign non-neoplastic mass of the heart that is sometimes found due to embolic events. Most cases of CAT are treated with surgical removal to prevent future embolic events. However, the tre...
Case Reports
Acta medica Okayama. 2025 Apr;79(2):135-138. DOI:10.18926/AMO/68653 2025
A Case of Retinitis Pigmentosa Diagnosed with Severe Anterior Capsule Contraction after Cataract Surgery [0.03%]
白内障术后严重前囊膜收缩1例报告
Akihiro Tsuji,Yusuke Shiode,Shuhei Kimura et al.
Akihiro Tsuji et al.
A 66-year-old woman presented with significant anterior capsule contraction and intraocular lens dislocation in both eyes 4 months after cataract surgery. Postoperative examinations such as fluorescein angiography, Goldmann perimetry, and e...
Case Reports
Acta medica Okayama. 2025 Apr;79(2):129-134. DOI:10.18926/AMO/68652 2025
Macular Hole Formation Six Months after Hemorrhage Displacement for Submacular and Henle Fiber Layer Hemorrhage due to Retinal Arterial Macroaneurysm Rupture [0.03%]
视网膜动脉巨大瘤破裂导致的下层和Henle纤维层下出血移位6个月后形成黄斑孔
Riku Akatsuka,Shuhei Kimura,Ryo Matoba et al.
Riku Akatsuka et al.
A 78-year-old woman presented with sudden vision loss and central scotoma. Visual acuity in the right eye was 20/222, with submacular hemorrhage (SMH) and Henle fiber layer hemorrhage (HFLh) due to retinal arterial macroaneurysm (RAM) ruptu...
Case Reports
Acta medica Okayama. 2025 Apr;79(2):123-127. DOI:10.18926/AMO/68651 2025
From a Congenital Defect to Cancer: A Case of Squamous Cell Carcinoma in a Neglected Myelomeningocele [0.03%]
从先天性畸形到癌症：一个被忽视的脊膜脊髓膨出症继发鳞状细胞癌病例报告
Abhishek Gautam,Rahul Kenawadekar,Virupaxi Hattiholi et al.
Abhishek Gautam et al.
Neural tube defects are common congenital anomalies, typically presenting early due to visible swelling and/or neurological deficits. Rarely, cystic swellings are neglected until adulthood, with only 14 cases of malignancy developing in an ...
Case Reports
Acta medica Okayama. 2025 Apr;79(2):117-121. DOI:10.18926/AMO/68650 2025
Effectiveness of Postoperative Irradiation in Patients with cN0 Early Breast Cancer Treated with Sentinel Lymph Node Surgery [0.03%]
哨兵淋巴结手术治疗的cN0期乳腺癌患者术后放疗的有效性研究
Hiroshi Isozaki,Sasau Matsumoto,Takehiro Takama et al.
Hiroshi Isozaki et al.
To evaluate the effectiveness of postoperative irradiation (POI) for patients with cN0 early breast cancer, we retrospectively analyzed the cases of 650 consecutive breast cancer patients who underwent sentinel lymph node (SLN)-guided surge...