An Integrative Approach to Biomarker Development in Psoriatic Arthritis [0.03%]
银屑病关节炎生物标志物整合型开发方法学研究进展
Christopher T Ritchlin
Christopher T Ritchlin
The recent discovery that the interleukin 23/Th17 pathway is pivotal in the pathogenesis of psoriatic arthritis (PsA) creates new opportunities for the development of mechanistic biomarkers that will assist in the diagnosis and management o...
Ennio Lubrano,Wendy Joanne Parsons,Antonio Marchesoni et al.
Ennio Lubrano et al.
This review seeks to update the state of the art of axial psoriatic arthritis (axPsA). The definition and assessment of axPsA can be problematic because no agreement and no definitive data on this topic have been published, resulting in unc...
Antonio Del Puente,Antonella Esposito,Luisa Costa et al.
Antonio Del Puente et al.
Psoriatic arthritis (PsA) can have peculiar effects on bone, including mechanisms of bone loss such as erosions, but also of bone formation, such as ankylosis or periostitis. The aim of the present study was to describe the prevalence of fr...
Ignazio Olivieri,Salvatore D&#x;Angelo,Michele Gilio et al.
Ignazio Olivieri et al.
In the early 1970s, Moll and co-workers formulated the unified concept of spondyloarthritides, a group of conditions sharing similar clinical features. Subsequently, criteria for their classification have been proposed by Amor and coworkers...
Piercarlo Sarzi-Puttini,Valentina Varisco,Maria Chiara Ditto et al.
Piercarlo Sarzi-Puttini et al.
The introduction of new biological drugs for the treatment of rheumatoid arthritis and spondyloarthritis has led to the creation of a number of registries in Europe and the United States. Most of them are sponsored by national rheumatology ...
Fabrizio Cantini,Carlotta Nannini,Emanuele Cassarà et al.
Fabrizio Cantini et al.
Autoimmune anterior uveitis (AU) accounts for at least half of the cases of noninfectious uveitis, and similarly to spondyloarthritis (SpA), its occurrence is related to HLA-B27 positivity. AU is significantly more frequently found in HLA-B...
Raffaele Scarpa,Francesco Caso,Luisa Costa et al.
Raffaele Scarpa et al.
In 2006, the introduction of the concept "psoriatic disease" (PsD) extended the traditional idea of a condition confined to skin and joints. Now we consider PsD a systemic condition, in which the increased activity of tumor necrosis factor ...
Paolo Gionchetti,Carlo Calabrese,Fernando Rizzello
Paolo Gionchetti
Spondyloarthritis (SpA) is a group of diseases with similar clinical, radiologic, and serologic features, including SpA associated with inflammatory bowel disease (IBD-associated SpA). SpA is the most frequent extraintestinal manifestation ...
Joerg Christoph Prinz
Joerg Christoph Prinz
Translational research is a coordinated process that converts scientific knowledge about diseases from basic research into the development of therapeutic or diagnostic procedures in order to improve public health. Recent insights into the p...
Dafna D Gladman
Dafna D Gladman
The concept "treat to target" in rheumatology was first developed for rheumatoid arthritis. A similar attempt to develop such an approach for spondyloarthritis was unsuccessful because the assessment tools and target of therapy had not been...