Yi-Hsuan Tu,Bin Cheng,Ying Kuen Cheung
Yi-Hsuan Tu
We are concerned with the problem of estimating the treatment effects at the effective doses in a dose-finding study. Under monotone dose-response, the effective doses can be identified through the estimation of the minimum effective dose, ...
Qi Long
Qi Long
Motivated by a biomarker study for colorectal neoplasia, we consider generalized functional linear models where the functional predictors are measured with errors at discrete design points. Assuming that the true functional predictor and th...
Adaptive Isotonic Estimation of the Minimum Effective and Peak Doses in the Presence of Covariates [0.03%]
考虑协变量时自适应等势估计最小有效和最大剂量
Changfu Xiao,Anastasia Ivanova
Changfu Xiao
We consider a problem of estimating the minimum effective and peak doses in the presence of covariates. We propose a sequential strategy for subject assignment that includes an adaptive randomization component to balance the allocation to p...
A random-sum Wilcoxon statistic and its application to analysis of ROC and LROC data [0.03%]
一种随机和Wilcoxon统计量及其在ROC与LROC数据分析中的应用研究
Liansheng Larry Tang,N Balakrishnan
Liansheng Larry Tang
The Wilcoxon-Mann-Whitney statistic is commonly used for a distribution-free comparison of two groups. One requirement for its use is that the sample sizes of the two groups are fixed. This is violated in some of the applications such as me...
Compare diagnostic tests using transformation-invariant smoothed ROC curves() [0.03%]
基于变换不变的平滑ROC曲线的诊断试验比较()
Liansheng Tang,Pang Du,Chengqing Wu
Liansheng Tang
Receiver operating characteristic (ROC) curve, plotting true positive rates against false positive rates as threshold varies, is an important tool for evaluating biomarkers in diagnostic medicine studies. By definition, ROC curve is monoton...
A Mass Redistribution Algorithm for Right Censored and Left Truncated Time to Event Data [0.03%]
一种针对截尾和 truncation 数据的 масс redistribution 算法
Xu Zhang,Mei-Jie Zhang,Jason Fine
Xu Zhang
Failure times are often right-censored and left-truncated. In this paper we give a mass redistribution algorithm for right-censored and/or left-truncated failure time data. We show that this algorithm yields the Kaplan-Meier estimator of th...
Proportional hazards model for competing risks data with missing cause of failure [0.03%]
具有失效原因缺失的竞争风险数据的比例 Hazard 模型
Seunggeun Hyun,Jimin Lee,Yanqing Sun
Seunggeun Hyun
We consider the semiparametric proportional hazards model for the cause-specific hazard function in analysis of competing risks data with missing cause of failure. The inverse probability weighted equation and augmented inverse probability ...
Guanqun Cao,Jing Wang,Li Wang et al.
Guanqun Cao et al.
We develop in this paper a new procedure to construct simultaneous confidence bands for derivatives of mean curves in functional data analysis. The technique involves polynomial splines that provide an approximation to the derivatives of th...
Changwon Lim,Pranab K Sen,Shyamal D Peddada
Changwon Lim
Toxicologists and pharmacologists often describe toxicity of a chemical using parameters of a nonlinear regression model. Thus estimation of parameters of a nonlinear regression model is an important problem. The estimates of the parameters...
Arnab Maity,Michael Sherman
Arnab Maity
Spatial modeling is typically composed of a specification of a mean function and a model for the correlation structure. A common assumption on the spatial correlation is that it is isotropic. This means that the correlation between any two ...