Edsel A Peña,Elizabeth H Slate,Juan R González
Edsel A Peña
Procedures for estimating the parameters of the general class of semiparametric models for recurrent events proposed by Peña and Hollander (2004) are developed. This class of models incorporates an effective age function encoding the effec...
Predicting Random Effects with an Expanded Finite Population Mixed Model [0.03%]
带有扩增有限总体混合模型的随机效应预测
Edward J Stanek rd,Julio M Singer
Edward J Stanek rd
Prediction of random effects is an important problem with expanding applications. In the simplest context, the problem corresponds to prediction of the latent value (the mean) of a realized cluster selected via two-stage sampling. Recently,...
A new class of mixture models for differential gene expression in DNA microarray data [0.03%]
DNA微阵列数据中差异表达基因的一种新的混合模型分类方法
Ming-Hui Chen,Joseph G Ibrahim,Yueh-Yun Chi
Ming-Hui Chen
One of the fundamental issues in analyzing microarray data is to determine which genes are expressed and which ones are not for a given group of subjects. In datasets where many genes are expressed and many are not expressed (i.e., underexp...
Man Sik Park,Montserrat Fuentes
Man Sik Park
Symmetry and separability of spatial-temporal covariances are the main assumptions that are frequently taken for granted in most applications because of the simplicity of constructing covariance structure. However, many studies in environme...
A case-control study relating railroad worker mortality to diesel exhaust exposure using a threshold regression model [0.03%]
利用阈值回归模型关联铁路工人死亡与柴油机排气暴露的病例对照研究
Mei-Ling Ting Lee,G A Whitmore,Francine Laden et al.
Mei-Ling Ting Lee et al.
A case-control study of lung cancer mortality in U.S. railroad workers in jobs with and without diesel exhaust exposure is reanalyzed using a new threshold regression methodology. The study included 1256 workers who died of lung cancer and ...
Development and Validation of Biomarker Classifiers for Treatment Selection [0.03%]
生物标志物分类器的开发和验证以选择治疗方法
Richard Simon
Richard Simon
Many syndromes traditionally viewed as individual diseases are heterogeneous in molecular pathogenesis and treatment responsiveness. This often leads to the conduct of large clinical trials to identify small average treatment benefits for h...
Generalized Self-Consistency: Multinomial logit model and Poisson likelihood [0.03%]
广义自一致性研究：多元logit模型和Poisson情形
Alex Tsodikov,Solomon Chefo
Alex Tsodikov
A generalized self-consistency approach to maximum likelihood estimation (MLE) and model building was developed in (Tsodikov, 2003) and applied to a survival analysis problem. We extend the framework to obtain second-order results such as i...
Some Geometric Methods for Constructing Decision Criteria Based On Two-Dimensional Parameters [0.03%]
Peter F Thall
Peter F Thall
This paper reviews two types of geometric methods proposed in recent years for defining statistical decision rules based on 2-dimensional parameters that characterize treatment effect in a medical setting. A common example is that of making...
Ma Zenia N Agustin,Edsel A Peña
Ma Zenia N Agustin
A class of tests for the hypothesis that the baseline hazard function in Cox's proportional hazards model and for a general recurrent event model belongs to a parametric family C identical with {lambda(0)(.; xi): xi in Xi} is proposed. Fini...