Relationship between compression pressure, mechanical strength and release properties of tablets [0.03%]
关于片剂压缩压力、机械强度和释放性能之间关系的研究
Olutayo Ademola Adeleye
Olutayo Ademola Adeleye
Tablets are a complex drug delivery system consisting of the active pharmaceutical ingredients and excipients. Tablet production involves a series of unit operations in which drugs and excipients are subjected to mechanical stresses, such a...
Influence of sodium starch glycolate, croscarmellose sodium and crospovidone on disintegration and dissolution of stevia-loaded tablets [0.03%]
羟丙纤维素、交联羧甲基纤维素钠和交联聚维酮对罗汉果片剂溶出度的影响研究
Abid Mehmood Yousaf,Faiza Naheed,Yasser Shahzad et al.
Abid Mehmood Yousaf et al.
Background: Sugar substitutes are used by diabetic, obese and calorie-conscious people. As artificial sweeteners are harmful to the body, natural sweeteners are more suitable. Sugar substitutes are available on the market...
[Applications of synthetic and semisynthetic polymers (Kollidon K25, Kollidon K90 and Hydroksyethylocellulose) as carriers of ketoprofen in solid oral prolonged release dosage forms. The impact of selected non-ionic surfactants (Tween 80 and Rofam 70) on the release kinetics] [0.03%]
合成及半合成聚合物(Kollidon K25、Kollidon K90和Hydroksyethylocellulose)作为酮洛芬固体口服缓释给药系统载体的应用。非离子型表面活性剂(Tween 80和Rofam 70)对释放动力学的影响
Wojciech Linka,Monika Kamińska,Michał Krzysztof Kołodziejczyk
Wojciech Linka
Background: Hydrophilic matrices used as oral forms of sustained release drugs are a suitable application medium for short-acting nonsteroidal anti-inflammatory drugs (NSAID) - ketoprofen. A properly selected hydrophilic ...
Study of the influence of cellulose derivatives on physical and analytical attributes of a drug product belonging to BCS class II [0.03%]
研究纤维素衍生物对BCS IV类药物产品物理和化学性质影响的研究
Magdalena Domosławska,Renata Pawlak-Morka,Łukasz Dobrzyński et al.
Magdalena Domosławska et al.
Background: Cellulose microcrystalline (MCC), hydroxypropyl methylcellulose (HPMC) and croscarmellose sodium are cellulose derivatives which are widely used in pharmaceutical technology. Although they are inert pharmaceut...
Formulation and solid state characterization of carboxylic acid-based co-crystals of tinidazole: An approach to enhance solubility [0.03%]
天尼达唑的基于羧酸盐共晶的制备及固体特性研究：提高溶解度的方法
Jyotsana R Madan,Rishikesh H Dagade,Rajendra Awasthi et al.
Jyotsana R Madan et al.
Background: Tinidazole (TNZ) is an anti-parasite drug used in the treatment of a variety of amebic and parasitic infections. It has low solubility in aqueous media and is categorized under Class II of the Biopharmaceutica...
Effects of media components and agricultural by-products on γ-polyglutamic acid production by Bacillus toyonensis As8 [0.03%]
培养基成分及农业副产物对胶质芽胞杆菌As8聚γ-谷氨酸产量的影响
Olubusola A Odeniyi,David S Avoseh
Olubusola A Odeniyi
Background: Poly-γ‑glutamic acid (γ‑PGA) provides an environmentally friendly alternative to plastic materials which have widely polluted the environment. ...
The polymorphism of statins and its effect on their physicochemical properties [0.03%]
他汀类药物多晶型及其对物理化学性质的影响
Marta Karaźniewicz-Łada,Karina Bąba,Filip Dolatowski et al.
Marta Karaźniewicz-Łada et al.
Polymorphism of pharmaceutical substances has a significant impact on their physicochemical properties, durability, bioavailability and consequently on their pharmacological activity. Solid dosage forms may exist in both crystalline and amo...
The preparation and physicochemical characterization of eprosartan mesylate-laden polymeric ternary solid dispersions for enhanced solubility and dissolution rate of the drug [0.03%]
用于提高药物溶解度和溶出速率的埃普洛沙坦甲磺酸盐载药聚乙烯亚胺三元固体分散体的制备与理化表征
Abid Mehmood Yousaf,Sundas Zulfiqar,Yasser Shahzad et al.
Abid Mehmood Yousaf et al.
Background: Eprosartan mesylate is a poorly water-soluble drug. It does not dissolve well in the aqueous gastrointestinal fluid, which means it is not absorbed well via the oral route, because a drug can cross cell membra...
Piotr Olczyk,Artur Małyszczak,Mariusz Kusztal
Piotr Olczyk
Dialysis membranes are the basic element of a hemodialyzer. Synthetic and natural materials characterized by various fiber arrangements are used in their production. The most up-to-date ones are made of synthetic polymers such as polyamide,...
Polyethylene terephthalate tape augmentation as a solution in recurrent quadriceps tendon ruptures [0.03%]
聚对苯二甲酸乙二醇酯带加固治疗股四头肌肌腱复发性断裂
Maciej Leciejewski,Aleksandra Królikowska,Paweł Reichert
Maciej Leciejewski
Quadriceps tendon rupture is a severe and demanding problem in knee surgery, especially when it is recurrent and when elderly patients are involved. It can have a devastating impact when it is a complication following knee arthroplasty. The...