Rapid selection of Andrographis paniculata medicinal plant materials based on major bioactive using near-infrared spectroscopy [0.03%]
基于近红外光谱的穿心莲药材材料快速选择及主药效成分ANDROGRAPHOLIDE累积预测模型研究
Sumaporn Kasemsumran,Waraporn Apiwatanapiwat,Krairuek Ngowsuwan et al.
Sumaporn Kasemsumran et al.
Abstract: The quantitative analysis of andrographolides in Andrographis paniculata plant materials is essential for pharmaceutical factories. This analysis cannot be done for all samples due to the conventional process us...
Extraction and quantification of some valuable flavonoids from pinecone of Pinus brutia via Soxhlet and Supercritical CO2 extraction: a comparison study [0.03%]
松果球果茋和杨梅皮素的索氏提取及超临界CO₂萃取性能比较研究
Levent Nuralın,Metin Gürü,Servet Çete
Levent Nuralın
In this study, the extraction of oil from pinecone of Pinus brutia was evaluated by supercritical CO2 (Sc-CO2) and Soxhlet extraction methods. The quercetin, rutin and kaempferol (QRK) contents of oil were analyzed one by one via HPLC. The ...
RETRACTED ARTICLE: Discovery of (E)- N-(4-cyanobenzylidene)-6-fluoro-3-hydroxypyrazine-2-carboxamide (cyanorona-20): the first potent and specific anti-COVID-19 drug [0.03%]
撤回文章：发现(E)-N-(4-氰基苯基亚甲基)-6-氟-3-羟基吡嗪-2-甲酰胺(氰奥拉纳-20)：第一个有效的抗COVID-19药物
Amgad M Rabie
Amgad M Rabie
Abstract: Specific inhibition of the viral RNA-dependent RNA polymerase (RdRp) of the newly-emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a very promising strategy for developing highly potent me...
An insight into the inhibitory mechanism of phytochemicals and FDA-approved drugs on the ACE2-Spike complex of SARS-CoV-2 using computational methods [0.03%]
计算方法研究植物化学成分和FDA批准药物抑制新型冠状病毒ACE2-Spike复合物的作用机制
Vinod Jani,Shruti Koulgi,V N Mallikarjunachari Uppuladinne et al.
Vinod Jani et al.
The S-glycoprotein (Spike) of the SARS-CoV-2 forms a complex with the human transmembrane protein angiotensin-converting enzyme 2 (ACE2) during infection. It forms the first line of contact with the human cell. The FDA-approved drugs and ph...
C3 amino-substituted chalcone derivative with selective adenosine r A1 receptor affinity in the micromolar range [0.03%]
一种具有微摩尔级腺苷a1受体亲和力的选择性c3-氨基取代查耳酮衍生物
Helena D Janse van Rensburg,Lesetja J Legoabe,Gisella Terre&#x;Blanche
Helena D Janse van Rensburg
Abstract: To identify novel adenosine receptor (AR) ligands based on the chalcone scaffold, herein the synthesis, characterization and in vitro and in silico evaluation of 33 chalcones (15-36 and 37-41) and structurally r...
An electrochemical label-free DNA impedimetric sensor with AuNP-modified glass fiber/carbonaceous electrode for the detection of HIV-1 DNA [0.03%]
用于检测HIV-1 DNA的掺AuNP玻璃纤维/碳电极的无标记dna阻抗传感器
Ece Ç Yeter,Samet Şahin,M Oguzhan Caglayan et al.
Ece Ç Yeter et al.
In this study, a highly sensitive, electrochemical, and label-free DNA impedimetric sensor was developed using carbonized glass fiber-coal tar pitch (GF-CTP) electrodes supported with gold nanoparticles (AuNPs) for the detection of HIV-1 ge...
Fluorescent, colourimetric, and ratiometric probes based on diverse fluorophore motifs for mercuric(II) ion (Hg2+) sensing: highlights from 2011 to 2019 [0.03%]
基于多种荧光团骨架的汞离子(Hg2+)荧光、比色及比率型探针检测材料：2011-2019年进展综述
Stephen Opeyemi Aderinto
Stephen Opeyemi Aderinto
Though it has not been shown to deliver any biological importance, mercuric(II) ion (Hg2+) is a deleterious cation which poses grievous effects to the human body and/or the ecosystem, hence, the need for its sensitive and selective monitori...
Methyl-2-arylidene hydrazinecarbodithioates: synthesis and biological activity [0.03%]
2-芳亚甲基碳二硫代肼类化合物的合成及其生物活性研究
Manojkumar Mahapatra,Umasankar Kulandaivelu,Philipp Saiko et al.
Manojkumar Mahapatra et al.
Methyl-2-arylidene hydrazine-carbodithioate has not been of particular interest to researchers even though its metal complexes are extensively reported on due to their biological activity. This study examined the cytostatic and antiviral ac...
Key side products due to reactivity of dimethylmaleoyl moiety as amine protective group [0.03%]
仲丁烯二酰胺类衍生物作为氨基保护基时的副反应及其主要产物研究
Mijoon Lee,Dusan Hesek,Bruce C Noll et al.
Mijoon Lee et al.
Dimethylmaleoyl (DMM) moiety has become an important amine protective group in sugar chemistry. We disclose herein that DMM-containing d-glucosamine analogues, because of their electrophilic nature, are prone to reactions with strong nucleo...
An effect of the tubular baffles configuration in an agitated vessel with a high-speed impeller on the power consumption [0.03%]
高搅拌速率下管板挡板结构对能耗的影响研究
Marta Major-Godlewska,Joanna Karcz
Marta Major-Godlewska
The results of the power consumption for an agitated vessel equipped with vertical tubular baffles and high-speed impeller are presented in the paper. Aqueous solutions of CMC were agitated within transitional range of the non-Newtonian liq...