Combining an Internal Pilot with an Interim Analysis for Single Degree of Freedom Tests [0.03%]
结合内部试点的单自由度检验的中期分析
John A Kairalla,Keith E Muller,Christopher S Coffey
John A Kairalla
An internal pilot with interim analysis (IPIA) design combines interim power analysis (an internal pilot) with interim data analysis (two stage group sequential). We provide IPIA methods for single df hypotheses within the Gaussian general ...
D H Glueck,K E Muller,A Karimpour-Fard et al.
D H Glueck et al.
The Benjamini-Hochberg procedure is widely used in multiple comparisons. Previous power results for this procedure have been based on simulations. This article produces theoretical expressions for expected power. To derive them, we make ass...
A Two-Latent-Class Model for Smoking Cessation Data with Informative Dropouts [0.03%]
具有信息丢失的戒烟数据的两潜在类别模型
Li Qin,Lisa A Weissfeld,Changyu Shen et al.
Li Qin et al.
Non ignorable missing data is a common problem in longitudinal studies. Latent class models are attractive for simplifying the modeling of missing data when the data are subject to either a monotone or intermittent missing data pattern. In ...
On Determining the Effects of Therapy on Disease Damage in Non- randomized Studies with Multiple Treatments: A study of Juvenile Myositis [0.03%]
非随机对照研究中多重处理对疾病损害影响的确定——以幼年性皮肌炎为例
Peter A Lachenbruch,Frederick W Miller,Lisa G Rider
Peter A Lachenbruch
This article discusses predicting damage in patients with juvenile myositis after treatment with various medications. These data were taken from medical records and not randomized. Investigators advocate using propensity scores for analysis...
BAYESIAN ANALYSIS OF REPEATED EVENTS USING EVENT-DEPENDENT FRAILTY MODELS: AN APPLICATION TO BEHAVIORAL OBSERVATION DATA [0.03%]
基于行为观察数据的事件相关 frailty 模型的贝叶斯分析方法研究重复事件
Getachew A Dagne,James Snyder
Getachew A Dagne
In social interaction studies, one commonly encounters repeated displays of behaviors along with their duration data. Statistical methods for the analysis of such data use either parametric (e.g., Weibull) or semi-nonparametric (e.g., Cox) ...
Testing for Covariate Effect in the Cox Proportional Hazards Regression Model [0.03%]
Cox比例风险回归模型中的协变量效应检验
Karthik Devarajan,Nader Ebrahimi
Karthik Devarajan
This paper presents methods for testing covariate effect in the Cox proportional hazards Model based on Kullback-Leibler divergence and Renyi's information measure. Renyi's measure is referred to as the information divergence of order γ (...
Nianjun Liu,Richard Bucala,Hongyu Zhao
Nianjun Liu
It is common to have missing genotypes in practical genetic studies. The majority of the existing statistical methods, including those on haplotype analysis, assume that genotypes are missing at random-that is, at a given marker, different ...
Application of Biostatistics and Bioinformatics Tools to Identify Putative Transcription Factor-Gene Regulatory Network of Ankylosing Spondylitis and Sarcoidosis [0.03%]
生物统计和生物信息学工具在识别强直性脊柱炎和肉芽肿病的转录因子-基因调控网络中的应用
Dongseok Choi,Srilakshmi M Sharma,Sirichai Pasadhika et al.
Dongseok Choi et al.
Transcription factors and corresponding cis-regulatory elements are considered key components in gene regulation. We combined biostatistics and bioinformatics tools to streamline identification of putative transcription factor-gene regulato...
Fast Computation by Block Permanents of Cumulative Distribution Functions of Order Statistics from Several Populations [0.03%]
若干总体顺序统计量分布函数的快速计算方法研究
D H Glueck,A Karimpour-Fard,J Mandel et al.
D H Glueck et al.
The joint cumulative distribution function for order statistics arising from several different populations is given in terms of the distribution functions of the populations. The computational cost of our formula in the case of two populati...
Assessment of Population Structure and Its Effects on Genome-Wide Association Studies [0.03%]
人群结构的评估及其对全基因组关联研究的影响
Hongyan Xu,Varghese George
Hongyan Xu
Large-scale genome-wide association studies are promising for unraveling the genetic basis of complex diseases. However, population structure is a potential problem, the effects of which on genetic association studies are controversial. Qua...