Validation of Nonparametric Two-Sample Bootstrap in ROC Analysis on Large Datasets [0.03%]
大型数据集上ROC分析中的非参数两样本Bootstrap法的验证研究
Jin Chu Wu,Alvin F Martin,Raghu N Kacker
Jin Chu Wu
The nonparametric two-sample bootstrap is applied to computing uncertainties of measures in ROC analysis on large datasets in areas such as biometrics, speaker recognition, etc., when the analytical method cannot be used. Its validation was...
Mixed-Effects Models with Skewed Distributions for Time-Varying Decay Rate in HIV Dynamics [0.03%]
具有偏态分布的混合效应模型在HIV动力学中描述时间变化的衰减率问题中的应用
Ren Chen,Yangxin Huang
Ren Chen
After initiation of treatment, HIV viral load has multiphasic changes, which indicates that the viral decay rate is a time-varying process. Mixed-effects models with different time-varying decay rate functions have been proposed in literatu...
An Efficient Operator for the Change Point Estimation in Partial Spline Model [0.03%]
分段样条模型中有效求解变点的算子方法研究
Sung Won Han,Hua Zhong,Mary Putt
Sung Won Han
In bio-informatics application, the estimation of the starting and ending points of drop-down in the longitudinal data is important. One possible approach to estimate such change times is to use the partial spline model with change points. ...
EM Estimation for Finite Mixture Models with Known Mixture Component Size [0.03%]
已知混合成分规模的有限混合模型中的EM估计方法
Chen Teel,Taeyoung Park,Allan R Sampson
Chen Teel
We consider the use of an EM algorithm for fitting finite mixture models when mixture component size is known. This situation can occur in a number of settings, where individual membership is unknown but aggregate membership is known. When ...
Exact Statistical Tests for Heterogeneity of Frequencies Based on Extreme Values [0.03%]
基于极值的频率分布异质性精确统计检验方法研究
Chih-Chieh Wu,Roger C Grimson,Sanjay Shete
Chih-Chieh Wu
Sophisticated statistical analyses of incidence frequencies are often required for various epidemiologic and biomedical applications. Among the most commonly applied methods is Pearson's χ2 test, which is structured to detect non-specific ...
Two-Step Hypothesis Testing When the Number of Variables Exceeds the Sample Size [0.03%]
变量数量超过样本量时的两步假设检验方法
Yueh-Yun Chi,Keith E Muller
Yueh-Yun Chi
Medical images and genetic assays typically generate data with more variables than subjects. Scientists may use a two-step approach for testing hypotheses about Gaussian mean vectors. In the first step, principal components analysis (PCA) s...
A Numerical Method for Estimating the Variance of Age at Maximum Growth Rate in Growth Models [0.03%]
生长模型中估计最大增长率时滞变差的数值方法
Semhar Beyene,V Ramakrishnan
Semhar Beyene
Studies on maturation and body composition mention age at peak height velocity (PHV) as an important measure that could predict adulthood outcome. The age at PHV is often derived from growth models such as the triple logistic fitted to the ...
APPROXIMATING POWER OF THE UNCONDITIONAL TEST FOR CORRELATED BINARY PAIRS [0.03%]
相关二元组的无条件检验的近似功效研究
Grace R Selicato,Keith E Muller
Grace R Selicato
We provide a simple and good approximation of power of the unconditional test for two correlated binary variables. Suissa and Shuster (1991) described the exact unconditional test. The most commonly used statistical test in this setting, Mc...
POPULATION ATTRIBUTABLE FRACTION AS A MEASURE OF HERITABILITY IN DICHOTOMOUS TWIN DATA [0.03%]
二分法孪生数据中的一种遗传度衡量标准——归因比例
Viswanathan Ramakrishnan,Leroy R Thacker
Viswanathan Ramakrishnan
In many genetic analyses of dichotomous twin data odds ratios have been used to test hypotheses on heritability and shared common environment effects of a given disease (Lichtenstein et. al., 2000, Ahlbom et. al., 1997, Ramakrishnan, et. al...
Rachael L Disantostefano,Keith E Muller
Rachael L Disantostefano
When testing equality of means from two independent normal populations, many statisticians prefer heterogeneity tolerant tests. Moser, Stevens, and Watts described the noncentral density and a numerical integration algorithm for computing p...