Colin D McCaig
Colin D McCaig
This first chapter covers essentials needed to understand the multiple roles of electrical forces that impinge on biology, over very different distances. Other less familiar electrical forces are also covered in the last chapter. ...
Autocrine, Paracrine, and Endocrine Signals That Can Alter Alveolar Macrophages Function [0.03%]
可以改变肺泡巨噬细胞功能的自分泌、旁分泌和内分泌信号
Yue Yang,Yun Wang
Yue Yang
Alveolar macrophages (AMs) are extremely versatile cells with complex functions involved in health or diseases such as pneumonia, asthma, and pulmonary alveolar proteinosis. In recent years, it has been widely identified that the different ...
Role of Oxytocin in Different Neuropsychiatric, Neurodegenerative, and Neurodevelopmental Disorders [0.03%]
催产素在不同的神经精神障碍，神经退行性病变和神经发育障碍中的作用
Aya A Ghazy,Omar A Soliman,Aya I Elbahnasi et al.
Aya A Ghazy et al.
Oxytocin has recently gained significant attention because of its role in the pathophysiology and management of dominant neuropsychiatric disorders. Oxytocin, a peptide hormone synthesized in the hypothalamus, is released into different bra...
The Emerging Pro-Algesic Profile of Transient Receptor Potential Vanilloid Type 4 [0.03%]
瞬时受体电位香草酸4逐渐显现的促疼痛特征
John P M White,Mario Cibelli,Istvan Nagy et al.
John P M White et al.
Transient receptor potential vanilloid type 4 (TRPV4) channels are Ca2+-permeable non-selective cation channels which mediate a wide range of physiological functions and are activated and modulated by a diverse array of stimuli. One of this...
Role of Distinct Fat Depots in Metabolic Regulation and Pathological Implications [0.03%]
不同脂肪库在代谢调节中的作用及其病理意义
Bijayashree Sahu,Ojas Tikoo,Benudhara Pati et al.
Bijayashree Sahu et al.
People suffering from obesity and associated metabolic disorders including diabetes are increasing exponentially around the world. Adipose tissue (AT) distribution and alteration in their biochemical properties play a major role in the path...
Roles of Intramolecular Interactions in the Regulation of TRP Channels [0.03%]
调控TRP通道的 intramolecular interaction 作用机制研究
Ruiqi Cai,Xing-Zhen Chen
Ruiqi Cai
The transient receptor potential (TRP) channels, classified into six (-A, -V, -P, -C, -M, -ML, -N and -Y) subfamilies, are important membrane sensors and mediators of diverse stimuli including pH, light, mechano-force, temperature, pain, ta...
Patch Clamp: The First Four Decades of a Technique That Revolutionized Electrophysiology and Beyond [0.03%]
膜片钳技术：四十年来改变电生理学及其他领域的一代新技术
Davide Lovisolo
Davide Lovisolo
Forty years ago, the introduction of a new electrophysiological technique, the patch clamp, revolutionized the fields of Cellular Physiology and Biophysics, providing for the first time the possibility of describing the behavior of a single...
Yan Zhang,Yun Wang
Yan Zhang
Pulmonary hypertension (PH) is a disease with high pulmonary arterial pressure, pulmonary vasoconstriction, pulmonary vascular remodeling, and microthrombosis in complex plexiform lesions, but it has been unclear of the exact mechanism of P...
Olimpia Daniela Frenț,Laura Vicaș,Tunde Jurca et al.
Olimpia Daniela Frenț et al.
Chitosan is a natural polysaccharide widespread in nature. It has many unique and attractive properties for the pharmaceutical field: it is biodegradable, safe, hypoallergenic, biocompatible with the body, free of toxicity, with proven anti...
Circulating Tumor Cells: Does Ion Transport Contribute to Intravascular Survival, Adhesion, Extravasation, and Metastatic Organotropism? [0.03%]
循环肿瘤细胞：离子转运是否促进其血管内存活、黏附、 extravasation 和器官特异性转移？
Christian Stock
Christian Stock
Survival in the circulation, extravasation from vasculature, and colonizing new tissues represent major steps of the metastatic cascade and pose a big challenge for metastasizing tumor cells. Tumor cells circulating in blood and lymph vesse...