Colin D McCaig
Colin D McCaig
Rapid tissue repair is also needed in the event of damage to blood vessels. Most of the essential steps that prevent us from bleeding to death involve the functions of Von Willebrand factor (VWF) and many of these are dependent on electrica...
Colin D McCaig
Colin D McCaig
Damage to the cell membrane can be life threatening for single-celled organisms. Several mechanisms of single-cell wound healing occur and aspects of these are regulated by electrical forces. ...
Colin D McCaig
Colin D McCaig
Cell membranes contain multiple charged lipids that bind proteins dynamically and their spatial organization on the inner/outer membrane leaflet, or in spatially localized areas has considerable biological importance. Myristoylated alanine-...
Colin D McCaig
Colin D McCaig
Epithelial tissues and the basement membranes they sit on did not appear for billions of years. Their appearance was delayed most likely by a lack of oxygen, which is required for collagen synthesis, and which only began to build up followi...
Colin D McCaig
Colin D McCaig
Epithelial sheets evolved the capacity to fold and reform to create a lumen and therefore new environments. For humans, forming a lumen during gastrulation has been viewed as perhaps the most crucial biological process of our life and it is...
Epithelia Are Scaffolds for Electricity-Dependent Molecular Interactions [0.03%]
上皮是一个依赖电势的分子相互作用的支架环境
Colin D McCaig
Colin D McCaig
Once multicellularity was thriving, a key development involved the emergence of epithelial layers that separated "inside" from "outside". Most epithelia then generate their own transepithelial electrical signals. So electrical forces were i...
Colin D McCaig
Colin D McCaig
Multiple single-celled life forms existed for millennia before some individual cells found ways of gathering together to form multicellular organisms. Several of the key elements that drove this step-change in life on Earth involved electri...
Colin D McCaig
Colin D McCaig
Electrical forces are widespread in single-celled organisms and underpin sophisticated communication systems. Bacterial biofilm colonies, for example, attract new members electrically. Bacteria also join together end to end and engage in lo...
Colin D McCaig
Colin D McCaig
How did life come into existence? How was the first membrane formed on Earth? And where? What were the conditions that promoted membrane creation and how were electrical forces essential for this to occur? ...
Colin D McCaig
Colin D McCaig
This covers the roles of electrical forces in space, in creating planets, including the Earth and in creating the conditions on Earth that make life possible. ...