[Current Theory on the Cerebral Mechanisms of Hypoxic PRE- and Postconditioning] [0.03%]
[缺氧脑保护的前适应和后适应机制研究进展]
E A Rybnikova,M O Samoilov
E A Rybnikova
An exposure of the organism to several episodes of mild hypoxia results in the development of brain hypoxic/ischemic tolerance, as well as cross-tolerance to the stressful factors of psychoemotional nature. Such kind of preconditioning by m...
R N Mustafin,E K Khusnutdinova
R N Mustafin
The article describes the role of transposable elements in the ontogenesis of eukaryotes. Adaptive and controlled transposition of mobile elements occurs at different stages of development of an organism, causing dramatic changes in the reg...
[Canonical and Noncanonical Mechanisms of Glucocorticoid Stress Hormones Action] [0.03%]
[糖皮质激素应激激素的作用机制( canonical 和非canonical)]
Hormones of stress, glucocorticoids, regulate numerous physiological processes and functions. These hormonal effects involve diverse mechanisms of action. Glucocorticoid receptors (GRs) are transcription factors which regulate gene expressi...
[Gasotransmitters: Physiological Role and Involvement in the Pathogenesis of the Diseases] [0.03%]
气体信号分子生理作用及其在疾病发生发展中的作用研究进展
O I Sukmansky,V P Reutov
O I Sukmansky
In recent decades, it has been found the existence of a new class of biologically active substances - gaseous mediators (gasotransmitters), performing in the cells the signaling function and with high specificity involved in the intercellul...
A S Bazyan
A S Bazyan
Based on the process needs, motivations and emotions, are describing molecular, cellular and systemic mechanisms of goal-direction motivated behavior. Goal-direction behavior is impossible without the orientation in space and forming a cogn...
S S Kolesnikov,M F Bystrova
S S Kolesnikov
Cell-to-cell communications and autocrine/paracrine regulations are mediated by an extracellular signaling network involving secretion of a variety of different factors, hormones, neurotransmitters, and other signaling molecules that are re...
V N Perfilova,I N Tyurenkov
V N Perfilova
The data on the structure, location and functions of the metabotropic glutamate receptor is shown. The family consists of 8 mGluRs subtypes and is divided into three groups: I group--mGluRs1/mGluRs5, II group--mGluRs2/mGluRs3, III group--mG...
R N Mustafin
R N Mustafin
The review presents the model of evolution with the participation of selfish genetic elements, the origin of which is directly related to the evolutionary transformation of living organisms, the genome of which is represented by viral seque...
[Molecular Mechanisms of Functional Activity Decreasing of the Skin Cells With Its Aging] [0.03%]
[皮肤老化过程中细胞功能活性下降的分子机制]
V Kh Khavinson,N S Linkova,E O Kukanova et al.
V Kh Khavinson et al.
The article discusses the pool of signaling molecules that regulate the functional activity of the skin cells. Molecules of apoptosis and cells skin aging are p53, p21, p15, Cdk 4/6 and Bcl-2. Inflammation in skin fibroblasts are realized t...
E V Lopatina,A V Kipenko,V A Penniyaynen et al.
E V Lopatina et al.
Literature and our data suggest the regulatory action of a number of biologically active substances (catecholamines, cardiac glycosides, β-blockers, angiotensin-converting-enzyme inhibitor) on the growth and proliferation of heart cells. B...