Signaling mechanisms regulating fibroblast activation, phenoconversion and fibrosis in the heart [0.03%]
调控心脏成纤维细胞活化、表型转换和纤维化的信号机制
Jessica MacLean,Kishore B S Pasumarthi
Jessica MacLean
Cardiac fibroblasts (CFs) maintain the cardiac extracellular matrix (ECM) through myocardial remodelling. The remodelling process can become dysregulated during various forms of heart disease which leads to an overall accumulation of ECM. T...
Regulation of Giα protein expression by vasoactive peptides in hypertension: molecular mechanisms [0.03%]
血管活性肽通过分子机制调节高血压中的Giα蛋白表达
Yuan Li,Madhu B Anand-Srivastava
Yuan Li
Guanine nucleotide regulatory proteins (G proteins) play a key role in the regulation of various signal transduction systems, including adenylyl cyclase/cAMP and phospholipase C (PLC)/phosphatidyl inositol (PI) turnover, which are implicate...
Involvement of the early growth response protein 1 in vascular pathophysiology: an overview [0.03%]
早起生长反应蛋白1在血管病理生理中的作用：综述
Estelle R Simo Cheyou,Viktoria Youreva,Ashok K Srivastava
Estelle R Simo Cheyou
Hyperactivation of proliferative and growth promoting pathways underlies the progression of vessel remodeling, leading to vascular dysfunction. An upregulation of early growth response protein 1 (Egr-1), a zinc finger transcription factor h...
Sajal Chakraborti,Animesh Chowdhury,Md Nur Alam et al.
Sajal Chakraborti et al.
Aneurysms develop as a result of chronic inflammation of vascular bed, where progressive destruction of structural proteins, especially elastin and collagen of smooth muscle cells has been shown to manifest. The underlying mechanisms are an...
Implications of fundamental signalling alterations in diabetes mellitus-associated cardiovascular disease [0.03%]
糖尿病相关心血管疾病的根本信号改变的含义
Pitchai Balakumar
Pitchai Balakumar
The chronic diabetes mellitus (DM) is a major risk factor for cardiovascular disease. The incidence of cardiovascular disease might be a foremost cause of morbidity and mortality in patients afflicted with DM. In fact, DM is associated with...
Mechanisms for the defects in phospholipid signal transduction in diabetic cardiomyopathy [0.03%]
糖尿病心肌病中磷脂信号转导缺陷的机制研究进展
Paramjit S Tappia,Naranjan S Dhalla
Paramjit S Tappia
Although diabetic cardiomyopathy is associated with heart dysfunction and disturbance in cardiac sarcolemmal membrane phospholipid composition, the role of the different phospholipases and their related signaling mechanisms to altered funct...
Chakraborti Sajal
Chakraborti Sajal
In vitro anticancer activity of extracts of Mentha Spp. against human cancer cells [0.03%]
Mentha属植物体外抗肿瘤活性研究
Vikas Sharma,Shabir Hussain,Moni Gupta et al.
Vikas Sharma et al.
In vitro anticancer potential of methanolic and aqueous extracts of whole plants of Mentha arvensis, M. longifolia, M. spicata and M. viridis at concentration of 100 μg/ml was evaluated against eight human cancer cell lines--A-549, COLO-20...
Comparative Study
Indian journal of biochemistry & biophysics. 2014 Oct;51(5):416-9. DOI: 2014
DPPH radical scavenging activity and contents of H2O2, malondialdehyde and proline in determining salinity tolerance in chickpea seedlings [0.03%]
利用发芽苗的盐分耐受性评价其DPPH自由基清除能力及H2O2、丙二醛和脯氨酸含量测定法
Narinder Kaur,Arvind Kumar,Kamaljit Kaur et al.
Narinder Kaur et al.
The involvement of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and contents of H2O2, malondialdehyde (MDA) and proline was investigated in determining salinity tolerance among seedlings of thirty chickpea (Cicer arietin...
Exogenous application of putrescine at pre-anthesis enhances the thermotolerance of wheat (Triticum aestivum L.) [0.03%]
外施腐胺可增强小麦开花前的热忍性
Ranjeet R Kumar,Sushil K Sharma,Gyanendra K Rai et al.
Ranjeet R Kumar et al.
Antioxidant enzymes, besides being involved in various developmental processes, are known to be important for environmental stress tolerance in plants. In this study, the effect of treatment of 2.5 mM putrescine (Put), heat stress (HS -42 d...