An unusual patient with hypercalciuria, recurrent nephrolithiasis, hypomagnesemia and G227R mutation of Paracellin-1. An unusual patient with hypercalciuria and hypomagnesemia unresponsive to thiazide diuretics [0.03%]
一个罕见的高钙尿、复发性肾结石、低镁血症和Paracellin-1(G227R)突变患者案例及对此病例氢氯噻嗪无效性的研究
Faruk Kutluturk,Berna Temel,Bora Uslu et al.
Faruk Kutluturk et al.
A 19-year-old female patient with hypercalciuria and recurrent nephrolithiasis/urinary tract infection unresponsive to thiazide type diuretics is presented. The patient first experienced nephrolithiasis at the age of 4 years. Afterwards, re...
Analysis of bone mineral density and turnover in patients with cystic fibrosis: associations between the IGF system and inflammatory cytokines [0.03%]
囊性纤维化患者骨密度及骨转换的分析：胰岛素样生长因子系统与炎性细胞因子的相关性研究
Maria E Street,Cinzia Spaggiari,Maria A Ziveri et al.
Maria E Street et al.
Background: Cystic fibrosis (CF) patients present an increased risk of osteoporosis, and increased fracture rate. Several factors have been identified as modulators of bone metabolism and bone mineral density (BMD). ...
Central application of IGF-1 postpones time of vaginal opening in normally fed, but not in food-restricted rats [0.03%]
中央注射IGF-1可推迟正常喂养但不能推迟限制进食大鼠阴道开启时间
S Zeinoaldini,J J M Swarts,B J M Van de Heijning
S Zeinoaldini
Background/aims: Central but also peripheral IGF-1 is suggested to play a role in the initiation of puberty as it directly affects GnRH synthesis and release. A possible intermediate in the effects of IGF-1 on puberty mig...
Comparative Study
Hormone research. 2006;66(4):169-74. DOI:10.1159/000094144 2006
The sertoli cell--a hormonal target and 'super' nurse for germ cells that determines testicular size [0.03%]
曲细精管支持细胞——一种既能响应激素又能护理生精细胞并决定睾丸大小的“超级护士”细胞
Cecilia Petersen,Olle Soder
Cecilia Petersen
The somatic Sertoli cell plays an essential role in embryonic determination of male somatic sex and in spermatogenesis during adult life. One individual Sertoli cell supplies a clone of developing germ cells with nutrients and growth factor...
Does the rare A172G mutation of PTPN11 gene convey a mild Noonan syndrome phenotype? [0.03%]
PTPN11基因罕见的A172G突变会导致轻度努南综合征表型吗？
Sophia Kitsiou-Tzeli,Anna Papadopoulou,Christina Kanaka-Gantenbein et al.
Sophia Kitsiou-Tzeli et al.
Background: Noonan syndrome NS (OMIM 163950) is an autosomal dominant developmental disorder characterized mainly by typical facial dysmorphism, growth retardation and variable congenital heart defects. In unrelated indiv...
Case Reports
Hormone research. 2006;66(3):124-31. DOI:10.1159/000094145 2006
Intermittent recombinant growth hormone treatment in short children born small for gestational age: four-year results of a randomized trial of two different treatment regimens [0.03%]
短胎龄儿身材矮小的间歇性重组人生长激素治疗：两种不同疗法的四年期随机试验结果
D Simon,J Leger,A Fjellestad-Paulsen et al.
D Simon et al.
Background: Treatment of short children born small for gestational age SGA with recombinant human growth hormone r-hGH increases growth velocity during childhood. As in other indications, the growth velocity in these pati...
Randomized Controlled Trial
Hormone research. 2006;66(3):118-23. DOI:10.1159/000093832 2006
Evaluation of short stature, carbohydrate metabolism and other endocrinopathies in Bloom's syndrome [0.03%]
Bloom综合征的矮小、碳水化合物代谢及其它内分泌病的评价
Alejandro Diaz,Maria G Vogiatzi,Maureen M Sanz et al.
Alejandro Diaz et al.
Aims: To obtain an understanding of the etiology of proportional dwarfism and endocrinopathies of Bloom's syndrome BS. Methods: Admissi...
Randomized Controlled Trial
Hormone research. 2006;66(3):111-7. DOI:10.1159/000093826 2006
Screening for Pax8 mutations in patients with congenital hypothyroidism in South-West Germany [0.03%]
南德意志地方性先天性甲状腺功能减退症患者中Pax8基因突变的筛选研究
Kirsten Lanzerath,Markus Bettendorf,Christine Haag et al.
Kirsten Lanzerath et al.
Aims: To study the frequency of mutations in the Pax8 gene in a cohort of patients with congenital hypothyroidism (CH) in South West Germany. Methods: ...
Case Reports
Hormone research. 2006;66(2):96-100. DOI:10.1159/000093799 2006
Growth hormone and prolactin receptors in adipogenesis: STAT-5 activation, suppressors of cytokine signaling, and regulation of insulin-like growth factor I [0.03%]
生长激素和催乳素受体在脂肪细胞形成中的作用：STAT-5激活、细胞因子信号转导抑制物及对胰岛素样生长因子I的调节作用
Don Fleenor,Ramamani Arumugam,Michael Freemark
Don Fleenor
Growth hormone GH stimulates lipolysis in mature adipocytes and primary preadipocytes but promotes adipogenesis in preadipocyte cell lines. The lactogenic hormones (prolactin PRL and placental lactogen) also stimulate adipogenesis in preadi...
Is ultrasound-guided laser thermal ablation for parathyroid adenomas safe and effective? [0.03%]
超声引导的激光热疗治疗甲状旁腺瘤安全有效吗？
Maurizio Iacobone
Maurizio Iacobone