E Dennison,C Cooper
E Dennison
Osteoporosis constitutes a major public health problem through its association with age-related fractures. These fractures typically occur at the hip, spine and distal forearm. It has been estimated that the lifetime risk of a hip fracture ...
Effects of growth hormone replacement therapy on bone markers and bone mineral density in growth hormone-deficient adults [0.03%]
生长激素替代治疗对成人生长激素缺乏患者骨标志物和骨密度的影响
A G Nilsson
A G Nilsson
During the 1990s, interest in the effects of growth hormone deficiency (GHD) in adults increased, and several studies were performed to evaluate the effects of growth hormone (GH) substitution therapy in these patients. Because adults with ...
Bone markers and bone mineral density during growth hormone treatment in children with growth hormone deficiency [0.03%]
生长激素缺乏儿童在生长激素治疗期间骨转换标志物和骨矿密度的变化
C T Cowell,H J Woodhead,J Brody
C T Cowell
Growth hormone (GH) has a positive impact on muscle mass, growth and bone formation. It is known to interact with the bone-forming unit, with well-documented increases in markers of bone formation and bone resorption within weeks of the sta...
Growth hormone and osteoporosis: an overview of endocrinological and pharmacological insights from the Utah paradigm of skeletal physiology [0.03%]
生长激素与骨质疏松症——犹他州骨骼生理学范式的内分泌学和药理学见解概述
H M Frost
H M Frost
Multidisciplinary advances in skeletal physiology offer a new paradigm for the effects of growth hormone (GH) and other agents on bone and osteoporosis. The still-evolving Utah paradigm of skeletal physiology supplements earlier ideas with ...
C Wüster
C Wüster
There is some evidence that bone mass is reduced in the majority of adult patients with growth hormone deficiency (GHD), suggesting that such patients have an increased risk of fractures and clinically significant osteoporosis. To date, the...
H K Genant,C Gordon,Y Jiang et al.
H K Genant et al.
Noninvasive and/or nondestructive techniques are capable of providing more macro- or microstructural information about bone than standard bone densitometry. Although the latter provides important information about osteoporotic fracture risk...
Bone densitometry: assessing the effects of growth hormone treatment in adults [0.03%]
骨密度测定：评估生长激素治疗对成人患者的影响
S Ortolani
S Ortolani
Dual-energy X-ray absorptiometry (DXA) is the reference method for the measurement of bone mineral mass at different skeletal sites. It has been widely used in recent years to assess the effects of growth hormone (GH) treatment on bone meta...
Assessment of bone architecture with ultrasonometry: experimental and clinical experience [0.03%]
超声波检测骨结构的评估：实验和临床经验
R Cadossi,F de Terlizzi,V Canè et al.
R Cadossi et al.
Over the last decade, ultrasound technology has been introduced as a method of analysing bone tissue in clinical practice, and several studies have compared various ultrasound devices with dual-energy X-ray absorptiometry (DXA). Unlike DXA,...
Critical ages and stages of puberty in the accumulation of spinal and femoral bone mass: the validity of bone mass measurements [0.03%]
脊柱和股骨骨量积累的关键年龄和青春期阶段：骨量测量的有效性
G I Baroncelli,G Saggese
G I Baroncelli
In growing children, lumbar and femoral areal bone mineral density (aBMD), as measured by dual-energy X-ray absorptiometry (DXA), is influenced by skeletal growth and bone size. Correction of lumbar bone mineral density (BMD) for bone volum...
Growth hormone hypersecretion in a girl with neurofibromatosis type 1 and an optic nerve glioma: resolution following chemotherapy [0.03%]
神经纤维瘤病Ⅰ型伴视神经胶质瘤女孩生长激素分泌过多的化疗后缓解
A J Drake,S P Lowis,E Bouffet et al.
A J Drake et al.
Growth hormone hypersecretion is extremely rare in childhood. We report a girl with neurofibromatosis type 1, an extensive optic nerve glioma and growth hormone hypersecretion. She was treated with chemotherapy to prevent further extension ...
Case Reports
Hormone research. 2000;53(6):305-8. DOI:10.1159/000053188 2000