A Cyclization/Oxygenation Scheme for the Conversion of Polyenes into C3-Oxygenated Polycycles [0.03%]
用于将多烯转化为C3-含氧轮烷的环化/氧化体系
Michael J Geier,Michel R Gagné
Michael J Geier
Biferrocene-Based Diphosphine Ligands: Synthesis and Application of Walphos Analogues in Asymmetric Hydrogenations [0.03%]
基于联铁ocene的二膦配体：不对称氢化中Walaph类似物的应用合成与应用
Afrooz Zirakzadeh,Manuela A Groß,Yaping Wang et al.
Afrooz Zirakzadeh et al.
A total of four biferrocene-based Walphos-type ligands have been synthesized, structurally characterized, and tested in the rhodium-, ruthenium- and iridium-catalyzed hydrogenation of alkenes and ketones. Negishi coupling conditions allowed...
Metal-Arene Complexes with Indolo[3,2-c]-quinolines: Effects of Ruthenium vs Osmium and Modifications of the Lactam Unit on Intermolecular Interactions, Anticancer Activity, Cell Cycle, and Cellular Accumulation [0.03%]
含金属-烯烃的吲哚并[3,2-c]喹啉配合物：钌与锇及内酰胺单元变化对分子间相互作用、抗肿瘤活性、细胞周期和细胞积累的影响
Lukas K Filak,Simone Göschl,Petra Heffeter et al.
Lukas K Filak et al.
Six novel ruthenium(II)- and osmium(II)-arene complexes with three modified indolo[3,2-c]quinolines have been synthesized in situ starting from 2-aminoindoloquinolines and 2-pyridinecarboxaldehyde in the presence of [M(p-cymene)Cl(2)](2) (M...
Copper-Catalyzed Homo-Dimerization of Nitronates and Enolates under Oxygen Atmosphere [0.03%]
氧气氛围下硝基酯和烯醇酯的铜催化均二聚反应
Hien-Quang Do,Hung Tran-Vu,Olafs Daugulis
Hien-Quang Do
A method for copper-catalyzed oxidative dimerization of nitronates and enolates using oxygen as terminal oxidant has been developed. Cyclization through oxidative intramolecular coupling is also feasible for both nitronates and enolates. Th...
Daniel S Tabari,Daniel R Tolentino,Yann Schrodi
Daniel S Tabari
1(st) Generation Hoveyda-Grubbs olefin metathesis catalyst was purposely decomposed in the presence of ethylene yielding inorganic species that are inactive in the ring-closing metathesis (RCM) of benchmark substrate diethyldiallyl malonate...
A Three-Stage Mechanistic Model for Ammonia Borane Dehydrogenation by Shvo's Catalyst [0.03%]
舒沃催化剂催化氨硼烷脱氢的三阶段机理模型
Zhiyao Lu,Brian L Conley,Travis J Williams
Zhiyao Lu
We propose a mechanistic model for three-stage dehydrogenation of ammonia borane (AB) catalyzed by Shvo's cyclopentadienone-ligated ruthenium complex. We provide evidence for a plausible mechanism for catalyst deactivation, the transition f...
Synthesis of Copper(I) Thiolate Complexes in the Thioetherification of Aryl Halides [0.03%]
通过铜硫化物配合物介导的芳基卤化物的硫醚化反应合成铜硫化合物复杂体
Chaohuang Chen,Zhiqiang Weng,John F Hartwig
Chaohuang Chen
The copper(I) thiophenolato complexes 1-3 containing 1,10-phenanthroline (phen) and 2,9-dimethyl-1,10-phenanthroline (Me(2)phen) were isolated in excellent yields from reactions of [CuOtBu](4) with the dative ligands and subsequent addition...
NHC-Cu-Catalyzed Silyl Conjugate Additions to Acyclic and Cyclic Dienones and Dienoates. Efficient Site-, Diastereo- and Enantioselective Synthesis of Carbonyl-Containing Allylsilanes [0.03%]
用于无环和环状二烯酮及二烯酸酯的NHC-Cu催化硅共轭加成反应高效位阻、非对映异构体和对映选择性合成含羰基的烯丙基硅烷的有效方法
Kang-Sang Lee,Hao Wu,Fredrik Haeffner et al.
Kang-Sang Lee et al.
Efficient and highly diastereo- and enantioselective conjugate additions of phenyldimethylsilyl units to acyclic and cyclic dienones and dienoates are disclosed. The C-Si bond forming reactions are catalyzed by 2.0-2.5 mol % of a copper com...
Chiral Indoline Synthesis Via Enantioselective Intramolecular Copper-Catalyzed Alkene Hydroamination [0.03%]
手性吲哚的不对称合成： intramolecular铜催化烯烃氢胺化反应中的映体选择性研究
Benjamin W Turnpenny,Kiante L Hyman,Sherry R Chemler
Benjamin W Turnpenny
An enantioselective copper-catalyzed hydroamination / cyclization of N-sulfonyl-2-allylanilines for the synthesis of chiral 2-methylindolines is reported. Chiral 2-methylindolines are important subunits in drugs and bioactive compounds. Thi...
Kinetic and Spectroscopic Studies of Aerobic Copper(II)-Catalyzed Methoxylation of Arylboronic Esters and Insights into Aryl Transmetalation to Copper(II) [0.03%]
铜(II)催化芳基硼酸酯的甲氧基化反应的动力学和光谱研究及对芳基转金属化的启示
Amanda E King,Bradford L Ryland,Thomas C Brunold et al.
Amanda E King et al.
We previously reported a preliminary mechanistic study of aerobic Cu(OAc)(2)-catalyzed methoxylation of 4-tolylboronic ester (King, et al. J. Am. Chem. Soc., 2009, 131, 5044-5045), which revealed that aryl transmetalation from the boronic e...