Purification of influenza virus-like particles using sulfated cellulose membrane adsorbers [0.03%]
使用硫酸纤维素膜吸附剂纯化流感病毒样颗粒
Sofia B Carvalho,A Raquel Fortuna,Michael W Wolff et al.
Sofia B Carvalho et al.
Background: Vaccines based on virus-like particles (VLPs) are an alternative to inactivated viral vaccines that combine good safety profiles with strong immunogenicity. In order to be economically competitive, efficient m...
Effects of bed compression on protein separation on gel filtration chromatography at bench and pilot scale [0.03%]
床压缩对凝胶过滤填料在实验室及中试规模蛋白质分离的影响
Darryl Yc Kong,Spyridon Gerontas,Ross A McCluckie et al.
Darryl Yc Kong et al.
Background: Poorly packed chromatography columns are known to reduce drastically the column efficiency and produce broader peaks. Controlled bed compression has been suggested to be a useful approach for solving this prob...
Magnetic hydrophobic-charge induction adsorbents for the recovery of immunoglobulins from antiserum feedstocks by high-gradient magnetic fishing [0.03%]
通过高梯度磁钓鱼从抗血清资源中回收免疫球蛋白的磁性疏水电荷诱导吸附剂
Cláudia Sg Gomes,Adedayo Fashina,Alfred Fernández-Castané et al.
Cláudia Sg Gomes et al.
Background: The extraction of biopharmaceuticals from plasma and serum often employs overly complicated antiquated procedures that can inflict serious damage on especially prone protein targets and which afford low purifi...
Daniel Burgstaller,Walpurga Krepper,Josselyn Haas et al.
Daniel Burgstaller et al.
Background: Integrated continuous production technology is of great interest in biopharmaceutical industry. Efficient, flexible and cost effective methods for continuous cell removal have to be developed, before a fully c...
Mathematical modelling of expanded bed adsorption - a perspective on in silico process design [0.03%]
扩张床吸附的数学建模——一种计算机辅助工艺设计的观点
Victor Koppejan,Guilherme Ferreira,Dong-Qiang Lin et al.
Victor Koppejan et al.
Expanded bed adsorption (EBA) emerged in the early 1990s in an attempt to integrate the clarification, capture and initial product concentration/purification process. Several mathematical models have been put forward to describe its operati...
Anton A Kiss,Rob Geertman,Matthias Wierschem et al.
Anton A Kiss et al.
The chemical industry has witnessed many important developments during past decades largely enabled by process intensification techniques. Some of them are already proven at commercial scale (e.g. reactive distillation) while others (e.g. u...
Evaluation of fluorescent dyes to measure protein aggregation within mammalian cell culture supernatants [0.03%]
评估荧光染料在哺乳动物细胞培养上清液中测量蛋白质聚集方面的性能
Sheun Oshinbolu,Rachana Shah,Gary Finka et al.
Sheun Oshinbolu et al.
Background: A current challenge in bioprocessing is the ability to analyse critical quality attributes such as aggregation without prior purification. This study evaluated the use of fluorescent dyes (Bis-ANS, SYPRO Orang...
Review: Water recovery from brines and salt-saturated solutions: operability and thermodynamic efficiency considerations for desalination technologies [0.03%]
综述：从卤水和盐饱和溶液中回收水分：脱盐技术的可操作性和热力学效率考虑因素
Leland M Vane
Leland M Vane
Background: When water is recovered from a saline source, a brine concentrate stream is produced. Management of the brine stream can be problematic, particularly in inland regions. An alternative to brine disposal is reco...
Gas diffusion electrodes improve hydrogen gas mass transfer for a hydrogen oxidizing bioanode [0.03%]
气体扩散电极改善生物阳极的产氢速率
Pau Rodenas,Fangqi Zhu,Annemiek Ter Heijne et al.
Pau Rodenas et al.
Background: Bioelectrochemical systems (BESs) are capable of recovery of metals at a cathode through oxidation of organic substrate at an anode. Recently, also hydrogen gas was used as an electron donor for recovery of co...
Surface hydrophobicity and acidity effect on alumina catalyst in catalytic methanol dehydration reaction [0.03%]
表面疏水性和酸性对氧化铝催化剂催化甲醇脱水反应的影响研究
Ahmed I Osman,Jehad K Abu-Dahrieh,David W Rooney et al.
Ahmed I Osman et al.
Background: Methanol to dimethyl ether (MTD) is considered one of the main routes for the production of clean bio-fuel. The effect of copper loading on the catalytic performance of different phases of alumina that formed ...