[Discordance of estrogen receptor status between primary and metastatic breast cancer--possible reasons and prognostic value] [0.03%]
原发性与转移性乳腺癌雌激素受体状态不一致的原因及预后价值不容忽视
T A Bogush,A S Popova,E A Dudko et al.
T A Bogush et al.
The aim of the review was systematization of the data on discordance in expression of estrogen receptors between primary and metastatic breast cancer, different metastases and repeated analyses of the same tissue. The possible reasons for t...
[Preclinical investigation of pharmaceuticals impact against cytochrome P450 activity and prognosis of substrate affinity as means for providing substrate therapy safety] [0.03%]
[药物理化对细胞色素P450活性影响的临床前调查及底物亲和力预测以确保底物治疗的安全性]
E V Fomin,I Kh Baĭchorov,E V Shikh et al.
E V Fomin et al.
Tricyclic antidepressants, not influencing the P450 3A4 activity, are safe in combination with drugs of other groups used in the treatment of comorbid patients. Azaphen is is one of the agents most widely used in the clinical practice. The ...
[Role of intraosteal administration of antibiotics in treatment of local oral mucinous carcinoma] [0.03%]
[载药骨小梁植入治疗口腔黏液癌的实验研究]
V M Ivanov,O V Ivanova,M V Sheĭkin
V M Ivanov
The problems of prophylaxis of infectious complications in the treatment of oral local mucinous carcinoma are considered relevant to 204 respective cases. More favourable results of the combined and complex treatment of the patients were sh...
[Invasive mucormycosis in patients with hemoblastosis in St.-Petersburg] [0.03%]
侵袭性毛霉病在圣彼得堡的血液系统恶性肿瘤患者中的发生率及临床特征分析
S N Khostelidi,A G Volkova,M O Popova et al.
S N Khostelidi et al.
Thirty four patients with mucormycosis in 10 hospitals of St. Petersburg were observed in 2004-2013. The most frequent underlying diseases of mucormycosis were acute leukoses (64%). In 100% of the patients mucormycosis developed as a nosoco...
[Cycloferon as an agent for the anti-relapse therapy in patients with chronic hyperplastic sinusitis] [0.03%]
卡巴西利醇治疗慢性化生性鼻窦炎复发的疗效观察
I P Vasilenko,M G Romantsov,A I Kriukov et al.
I P Vasilenko et al.
The data on the efficacy of cycloferon as an agents of antirelapsing therapy in management of 123 patients with chronic hyperplastic sinusitis are presented. The drug induction of endogenous interferons was validated by the properties of th...
[Characteristics of antibiotic therapy in neonates with polyorgan insufficiency] [0.03%]
新生儿多器官功能障碍综合征的抗生素治疗特点分析
E N Serebriakova,D K Volosnikov,G A Glazyrina
E N Serebriakova
Polyorgan insufficiency (POI) is the main cause of death in ISU patients. The highest rates of morbidity and mortality due to POI are recorded among newborns. Antibbacterial therapy of probable infections processes is widely used in neonato...
[Microbial models in screening of inhibitors of sterol biosynthesis] [0.03%]
[微生物模式在sterol biosynthesis抑制剂筛选中的应用]
A S Trenin
A S Trenin
On the base of previously developed microbial models high effective scheme for screening of inhibitors of sterol biosynthesis (ISB) is proposed. It is based on cultivation of halophilic bacteria Halobacterium salinarum (former Halobacterium...
S V Sidorenko,I V Partina,V A Ageevets
S V Sidorenko
M G Romantsov,F I Ershov,A L Kovalenko et al.
M G Romantsov et al.
Interferon inductors of various chemical groups, belonging to antivirals, and induction of several types of endogenous interferon in blood serum are described. Cycloferon was shown efficient in the complex treatment of chronic hepatitis C, ...
[Microbial antibiotic resistance: resistome, its volume, diversity and development] [0.03%]
[微生物抗生素抗性：耐药基因组、储备库容量、多样性及进化]
K A Vinogradova,V G Bulgakova,A N Polin et al.
K A Vinogradova et al.
The known conceptions of resistome as a complex of all the antibiotic resistance genes in the genomes of all the microorganisms, pathogenic and nonpathogenic ones, in nature are considered. The data on the origin, evolution and distribution...