New Data on Molecular Targets of Tamoxifen Besides Estrogen Receptors, Their Clinical Significancy [0.03%]
除了雌激素受体新的他莫昔芬分子作用靶点及其临床意义
T A Bogush,B B Polezhaev,E A Dudko et al.
T A Bogush et al.
Tamoxifen is the first target agent with a high-end position in breast cancer therapy till now. In recent years experimental researches revealed new biological effects of tamoxifen on tumor cells. The present study continues the theme of th...
A A Khryanin,O V Reshetinikov
A A Khryanin
The review provides modern literature data on the system of interferons, their cells producers and target cells. Particular attention is paid to the immunomodulating effect of interferon-y. High efficacy of Ingaron in the treatment of vario...
Plant Extracts in Development of Medicinal Products of Various Therapeutic Value [0.03%]
植物提取物在各种治疗价值医药产品开发中的作用
I P Smirnova,O A Semkina,O V Bondarenko
I P Smirnova
Development, standardization and use of medicinal products of plant origin and various therapeutic value are described in the review. The literature data refer to the studies of some leading institutions of the Russian Federation and in par...
Macrolide Resistance and Its Molecular Genetic Mechanisms in Streptococcus pyogenes Isolated from Children [0.03%]
儿童分离的链球菌中大环内酯耐药性及其分子机制研究
L K Katosova,A V Lazareva,T A Khokhlova et al.
L K Katosova et al.
The frequency and mechanisms of resistance to macrolides in Streptococcus.pyogenes isolated within 3 periods: 2011-2012 (246 strains), 2013-2014 (273 strains) and from January to November of 2015 (120 strains) were studied. The strains of S...
Experimental Substantiation of Taurine Use in Prophylaxis of Isoniazid-Induced Neurotoxic Reactions [0.03%]
taurine预防异烟肼所致神经毒副反应的实验依据
G N Mozhokina,N A Elistratova
G N Mozhokina
The effect of taurine and vitamin B6 on the clinical process and mortality of experimental mice due to isoniazid was studied in an acute test. The use of taurine lowered the toxic effect of isoniazid, evident from delayed covulsions, their ...
Biologically Active Substances from Marine Hydrobionts with Antibacterial Activity in Composition of New Wound Dressings [0.03%]
具抗菌活性的海洋药源生物活性物质在新型创面敷料中的应用研究进展
T A Kuznetsova,N N Besednova,T S Zaporozhets et al.
T A Kuznetsova et al.
The data on the experimental study of the efficacy of the gel wound dressings based on chitosan and calcium alginate containing bioactive substances from marine hydrobionts with complex therapeutic action (sulfated polysaccharides from brow...
Electrooptical Assay for Record of Antibiotic Action on Microbial Cells [0.03%]
电光分析在抗生素的抗菌作用测定中的应用研究英文题名：Electrooptical assay for record of antibiotic action on microbial cells
O I Guliy,V D Bunin,O V Ignatov
O I Guliy
Development of rapid and sensitive procedures for determination of microbial resistance to antibiotics is one of the most urgent trends in microbiology. The problem is shown to be solved by using electrooptical assay based on change of the ...
Disparities in Effectiveness of Pneumococcal Vaccine in Industrialized and Developing Countries: Is Vaccination Closing the Gap? [0.03%]
肺炎球菌疫苗在工业化国家和发达国家的效果差异：接种疫苗能否缩小这一差距？
Rachel Kornetsky,David Greenberg,Oana Falup-Pecurariu
Rachel Kornetsky
Background Streptococcus pneumoniae cause serious disease including pneumonia, meningitis and bacteremia and mortality.is seen most in developing countries. The aim of the study was to determine if the reduction in IPD aid pneumonia rates w...
Disparities in Effectiveness of Pneumococcal Vaccine in Industrialized and Developing Countries: Is Vaccination Closing the Gap? [0.03%]
肺炎球菌疫苗在发达国家与发展中国家中的效果差异：接种疫苗能否缩小这一差距？
Rachel Kornetsky,David Greenberg,Oana Falup-Pecurariu
Rachel Kornetsky
Background Streptococcus pneumoniae cause serious disease including pneumonia, meningitis and bacteremia and mortality.is seen most in developing countries. The aim of the study was to determine if the reduction in IPD aid pneumonia rates w...
Successful Tigecycline Use in Combined Therapy of Ventilator-Associated Hospital-Acquired Pneumonia: a Clinical Case [0.03%]
替加环素联合治疗呼吸机相关医院获得性肺炎1例及其评述
G V Rodoman,I R Sumedi,S K Zyryanov et al.
G V Rodoman et al.
In patients under artificial lung ventilation (ALV) there is often observed development of severe ventilator-associated pneumonia (VAP) due to polyresistant hospital pathogens. It should be noted that in the patient described here with the ...