Research Progress on How Multimodal Signals Regulate Neuronal Mitochondrial Homeostasis to Affect Diabetic Cognitive Impairment [0.03%]
多模态信号调控神经元线粒体稳态改善糖尿病认知障碍的研究进展
Ying Li,Pengwei Zhuang
Ying Li
Diabetic cognitive impairment (DCI) affects approximately 25%-35% of patients with diabetes and is characterized by progressive cognitive decline. Dysfunction of mitochondria-the energy factories within neurons-is considered a potential pat...
Lactobacillus mucosae Reduces Neuronal Oxidative Stress in Alzheimer's Disease via the Regulation of CB2 Signaling [0.03%]
乳酸菌粘膜亚种通过调节CB2信号传导降低阿尔茨海默病的神经元氧化应激
Yu Kong,Xinhuang Lv,Yao Yang et al.
Yu Kong et al.
Background: The probiotic Lactobacillus mucosae has been widely shown to have many positive effects. However, its neuroprotective effects and underlying mechanism in Alzheimer's disease (AD) remain elusive. ...
Digital Twins in Neurology Care: Evidence, Limitations, and a Path Forward [0.03%]
神经病学护理中的数字孪生：证据、局限性及前进的道路
Parisa Gazerani
Parisa Gazerani
Digital twins are increasingly promoted in neurology as an advancement beyond conventional artificial intelligence, yet the term is often applied without conceptual or methodological rigor. Strict definitions describe digital twins as dynam...
Microenvironmental Regulation of Central Nervous System Myelination and Remyelination [0.03%]
中枢神经系统的髓鞘形成和再髓鞘化受微环境调节
Yuxuan Wang,Lingzhen Tan,Lin Lao et al.
Yuxuan Wang et al.
Both myelination and remyelination in the central nervous system (CNS) rely on the differentiation of oligodendrocyte precursor cells (OPCs) into mature oligodendrocytes (OLs). However, the microenvironment and underlying mechanisms of thes...
Influence of Gait Speed on Spatiotemporal Parameters in Advanced Parkinson's Disease Following Subthalamic Nucleus Deep Brain Stimulation [0.03%]
subthalamic核深部脑刺激后步态速度对晚期帕金森病时空参数的影响
Daniela Sýkorová,Barbora Kolářová,Petr Kolář et al.
Daniela Sýkorová et al.
Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor and non-motor symptoms. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a recognized treatment for a...
Molecular Mechanisms and Potential Biomarkers of Neuropsychiatric Disorders in Parkinson's Disease [0.03%]
帕金森病的精神障碍分子机制及潜在生物标志物研究
Wojciech Owecki,Anna Futyma,Olga Kokorniak et al.
Wojciech Owecki et al.
Parkinson's disease (PD) is the second most common degenerative disease of the central nervous system, characterized by both motor and non-motor disorders. Non-motor disorders include dementia, depression, and anxiety. The prevalence of dem...
Activation of the p62/Keap1/Nrf2 Pathway Protects Against Ferroptosis in Cerebral Ischemia-Reperfusion Injury [0.03%]
p62/Keap1/Nrf2信号通路活化通过对抗铁死亡作用来保护缺血再灌注脑损伤
Canwen Liu,Xuanyi Dong,Biao Tang
Canwen Liu
Background: Protein p62 interacts with Kelch-like ECH-associated protein 1 (Keap1) competitively, triggering the oxidative stress response mediated by NF-E2-related factor 2 (Nrf2) and preventing ferroptosis in SH-SY5Y ce...
"See What I Mean?" Linguistic Digital Markers of Cognitive Decline in Nursing Home Residents [0.03%]
“你看得懂吗？”护理机构居民认知衰退的言语数字标记
Sonja Cecchetti,Andrew T Duchowski,Marco Cavallo
Sonja Cecchetti
Background: Cognitive decline in nursing homes is often under-recognized. Access to specialized neuropsychological assessments, which involve detailed evaluations of how the brain influences behavior and thinking, is ofte...
Observational Study
Journal of integrative neuroscience. 2026 May 26;25(5):49652. DOI:10.31083/JIN49652 2026
STING Mediates Necroptosis in Hippocampal Neurons of Mice With Sepsis-Associated Encephalopathy [0.03%]
STING介导败血症相关性脑病小鼠海马神经元坏死性凋亡
Xiaofeng Guo,Baocheng Cang,Yunhu Bai et al.
Xiaofeng Guo et al.
Background: Sepsis-associated encephalopathy (SAE) is a common and severe neurological syndrome induced by sepsis and characterized by brain dysfunction. The incidence of SAE is as high as 76%. After onset, the mortality ...
Electroacupuncture Combined With Paroxetine Improves Depression-Like Behavior in Rats by Regulating SIRT2/AMPAR in the Hippocampal Dentate Gyrus [0.03%]
电针联合帕罗西汀通过调控海马齿状回SIRT2/AMPA受体改善大鼠抑郁样行为
Zhinan Zhang,Shengtao Huang,Zheng Li et al.
Zhinan Zhang et al.
Background: Evidence from both clinical trials and animal studies indicates that electroacupuncture (EA) combined with antidepressants is more effective and has fewer side effects in the treatment of depression. In this s...