Physiological Regulatory Mechanisms of Neurovascular Coupling and the Role of Its Dysfunction in Neurological Diseases [0.03%]
神经血管耦合的生理调节机制及其功能障碍在神经系统疾病中的作用
Aili Wang,Jing Li,Huaie Liu et al.
Aili Wang et al.
Neurovascular coupling (NVC) is a fundamental physiological process that regulates cerebral blood flow in response to neuronal activity. This mechanism ensures the efficient delivery of oxygen and glucose to active brain regions while clear...
Yongxiang Zhang,Binghong Chen,Yuanxiang Lin et al.
Yongxiang Zhang et al.
Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease. No effective treatments have yet been found for ALS, primarily because the molecular mechanisms that underlie its pathogenesis are unknown. Although animal models a...
Integrating Multimodal Neuroimaging and Physical-Health Markers for Autism Spectrum Disorder in the ABCD Study [0.03%]
基于ABCD研究的自闭症谱系障碍的多模态神经影像与生理健康标志物整合研究
Dorin Zeevi,Hector Acosta-Rodriguez,Pratheek Bobba et al.
Dorin Zeevi et al.
Background: Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by diverse presentations, which complicates the identification of consistent biological markers. This study examined wheth...
Pressing Intervention Alleviates Pain in Rats With Myofascial Trigger Points via the TRPV1 Channel in Unmyelinated C-Type Sensory Nerve Fibers [0.03%]
presses干预通过C型无髓鞘感觉神经纤维中的TRPV1通道缓解肌筋膜触发点大鼠的疼痛
Yuqiao Zhang,Liya Tang,Xinyue Lv et al.
Yuqiao Zhang et al.
Background: Although pressing intervention is widely used clinically to alleviate pain associated with chronic myofascial trigger points (MTrPs), the mechanisms by which it modulates pain via sensory nerves remain unclear...
Response to "Considerations for Transcranial Direct Current Stimulation to Improve Gait Performance in the Elderly" [0.03%]
对「经颅直流电刺激改善老年人步行功能的思考」的回应
Beom Jin Choi,Hajun Lee,Nyeonju Kang
Beom Jin Choi
Overexpression of IL7R Attenuates Cerebral Ischemia-Reperfusion Injury by Inhibiting Apoptosis [0.03%]
IL7R过表达通过抑制细胞凋亡削弱脑缺血再灌注损伤
Shiqi Yang,Qian Su,Wenting Liu et al.
Shiqi Yang et al.
Background: Cerebral ischemia-reperfusion injury (CIRI) represents the most critical pathological event in the evolution of ischemic stroke (IS). Apoptosis is particularly important in CIRI pathophysiology. The interleuki...
Glymphatic Clearance Dynamics in Traumatic Brain Injury: Mechanisms, Imaging Biomarkers, and Application Prospects [0.03%]
创伤性脑损伤中的糖淋巴清除动力学：机制、影像生物标志物及应用前景
Tao Yang,Yongxiang Yang,Mu Yuan et al.
Tao Yang et al.
The pathological increase in brain catabolites after traumatic brain injury strongly correlates with a higher risk of neurodegenerative disease. This review examines the pathogenic role of glymphatic clearance dysfunction in that process. T...
Exercise Suppresses Insulin Resistance: A Potential Mechanism for Improving the Interaction Between Type 2 Diabetes and Alzheimer's Disease [0.03%]
运动抑制胰岛素抵抗：改善2型糖尿病与阿尔茨海默病相互作用的潜在机制
Bo Wang,Yuping Shao,Rongxiang Liang
Bo Wang
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by hyperglycemia, hyperinsulinemia, and impaired insulin sensitivity. Although classified as a metabolic disorder, T2DM also contributes to cognitive decline. Alz...
Altered Neural Activity and Functional Connectivity of Dorsolateral Prefrontal Cortex Associated With Cognitive Impairment in Patients With End-Stage Renal Disease [0.03%]
终末期肾病患者认知障碍与背外侧前额叶皮层异常的神经活动和功能连接有关
Jie Fang,Lingling Guo,Hongting Xu et al.
Jie Fang et al.
Background: Executive dysfunction is the most prominent feature of cognitive impairment in patients with end-stage renal disease (ESRD). The dorsolateral prefrontal cortex (DLPFC) is a central region for the regulation of...