Research Progress on the Relationship Between Gastrointestinal Diseases and Neural Nuclei in Animal Models [0.03%]
动物模型胃肠疾病与神经核团关系的研究进展
Jing Xiong,Jiake Zou,Xiao Deng et al.
Jing Xiong et al.
Gastrointestinal (GI) diseases are manifestations of abnormal brain-gut interactions, which are closely related to brain functions. Systematic sorting of the central mechanisms related to GI functions is of great clinical significance for p...
Long-Term Orchestral String Learning and Event-Related Potentials of Inhibitory Control in Children From Disadvantaged Communities [0.03%]
长期管弦乐团弦乐学习与弱势群体儿童抑制控制能力事件相关电位的研究
Taylor Hirsch,Amedeo DAngiulli
Taylor Hirsch
Background: Children from low socioeconomic status (SES) backgrounds are at increased risk for delays in executive function (EF), particularly inhibitory control and attentional regulation. Orchestral string music trainin...
Bone Marrow-Derived Mesenchymal Stromal Cells Alleviate Bone Cancer Pain by Modulating Microglial Polarization: Involvement of the Nrf2/HO-1 Pathway [0.03%]
骨髓来源间充质干细胞通过调节小胶质细胞极化缓解骨癌痛:Nrf2/HO-1通路的介导作用
Xinyu Lu,Penghui Ren,Jing Zhang et al.
Xinyu Lu et al.
Background: Dysregulated polarization of spinal microglia is a key contributor to the pathophysiology of bone cancer pain (BCP). Bone marrow-derived mesenchymal stromal cells (BMSCs) have demonstrated significant analgesi...
Metabolic Brain Network Reorganization in Temporal Lobe Epilepsy With Aware or Impaired Awareness Seizures [0.03%]
具有清醒或意识受损发作的颞叶癫痫患者的代谢性脑网络重组
Jingke Xiao,Fan Yang,Hanlin Zhang et al.
Jingke Xiao et al.
Background: Temporal lobe epilepsy (TLE) is increasingly recognized as a dysfunction of the brain network. However, the topological alterations of the metabolic brain network underlying impaired awareness seizures (IAS) r...
Longitudinal Reorganization of Local Brain Activity Following Acute Basal Ganglia Infarction: Combined Metrics of Amplitude and Dynamics Reveal Neural Substrates Underlying Motor Recovery [0.03%]
急性基底节梗死后的纵向脑局部活动重组:联合振幅和动力学指标揭示运动功能恢复的神经基础
Shijian Chen,Jian Zhang,Yayuan Liu et al.
Shijian Chen et al.
Background: In this study, we focused on exploring long-term trends and the clinical relevance of brain remodeling in acute basal ganglia cerebral infarction (BGCI) using percent amplitude of fluctuation (PerAF) and dynam...
The Neuroprotective Role of a Caspase-1 Inhibitor Against Apoptosis via Inhibition of Glial Hyperactivation in a Mouse Model of Epilepsy [0.03%]
一种半胱氨酸蛋白酶-1抑制剂通过抑制癫痫小鼠模型中的神经胶质细胞活化过度来对抗细胞凋亡的神经营养保护作用研究
Hui Cai,Xinran Xu,Xuerui Zhuo et al.
Hui Cai et al.
Background: Epilepsy is a central nervous system disorder characterized by abnormal neuronal discharges in the brain. The purpose of this study was to investigate the protective effects of a caspase-1 inhibitor on glial h...
Janie M Ondracek
Janie M Ondracek
How do neural circuits change to incorporate newly learned events? After decades of research, we now have a good understanding of the diversity and duration of memory types, the context-specifics of learning regimes, and the brain areas tha...
Tea Polyphenols Protect the Blood-Brain Barrier Structure in the Hippocampus of Early Diabetic Mice by Inhibiting the AGEs-RAGE Pathway [0.03%]
茶多酚通过抑制AGEs-RAGE信号通路保护糖尿病早期小鼠海马区血脑屏障结构
Zhiyong Xu,Yan Liu,Yan Yu
Zhiyong Xu
Background: Diabetic encephalopathy is a prevalent complication of diabetes mellitus, which is primarily characterized by hippocampal injury and blood-brain barrier (BBB) dysfunction. This study investigates the neuroprot...
Single-Cell and Integrative Analyses Uncover Therapeutic Potential of RFX1-Mediated Cuproptosis in PitNETs [0.03%]
单细胞及整合分析揭示PitNETs中RFX1介导的铜死亡抗肿瘤治疗潜力
Shuangjian Yang,Changqin Pu,Congcong Deng et al.
Shuangjian Yang et al.
Background: Pituitary neuroendocrine tumors (PitNETs) have different cell types and levels of growth. We do not fully understand why they grow so much. Cuproptosis is a new way that copper kills cells and it is important ...
Usefulness of Non-Contrast Electron Density Imaging for the Identification of Brain Tissue Changes in Large Vessel Occlusion Acute Ischemic Stroke [0.03%]
无创电子密度成像鉴别大血管闭塞急性脑梗死脑组织改变的价值
Santiago de Erausquin,Andres Polania,Gaston A Rodriguez-Granillo et al.
Santiago de Erausquin et al.
Background: Electron density (ED) imaging has shown the ability to discriminate between different soft tissue components in preliminary studies. We hypothesized that ED might improve the identification of brain tissue abn...