Brain Functional Alterations Associated With Postural Stability Across the Frailty Continuum: A Resting-State fMRI Study [0.03%]
脆弱性连续体下与平衡稳定性相关的脑功能改变:一项静息态fMRI研究
Sheng Huang,Yongyi Xu,Yaping Li et al.
Sheng Huang et al.
Background: Frailty is a common geriatric syndrome characterized by a progressive decline in physical function and an increased susceptibility to adverse outcomes, including falls. Although diminished postural stability i...
Evaluation of the Behavioral and Histopathological Outcomes of Two Cuprizone Administration Routes in a Mouse Model of Multiple Sclerosis [0.03%]
评估两种杯rizone给药途径在多发性硬化症小鼠模型中的行为学和病理学结果
Kholoud M Al-Otaibi
Kholoud M Al-Otaibi
Background: The cuprizone (CPZ) model has been used to study de- and re-myelination in mice; Previous studies have used different routes for CPZ intoxication, but the results were highly variable. ...
Role of Succinate Accumulation in Prolonged Febrile Seizure-Induced Neuronal Injury and Epileptic Seizures in Sprague-Dawley Rats [0.03%]
琥珀酸堆积在大鼠长时间发热性惊厥诱导的神经元损伤和癫痫发作中的作用
Yi Yuan,Xiaoqian Wang,Hua Zhou et al.
Yi Yuan et al.
Background: Though succinate accumulation is a vital contributor to overexcitation and reactive oxygen species (ROS) production, whether it contributes to febrile seizures (FS) is unclear. We sought to mechanistically exp...
Sevoflurane and Aβ1-42 Oligomers Synergistically Induce Morphological Changes of Astrocytes in the Hippocampus of Male Mice [0.03%]
异氟醚和Aβ1-42低聚物诱导小鼠海马区星形胶质细胞发生协同改变
Qinfang Shi,Arpit Kumar Pradhan,Siwei Dong et al.
Qinfang Shi et al.
Background: Reactive gliosis serves as a characteristic feature of the pathophysiology of Alzheimer's disease (AD). Nevertheless, the influence of anesthetics on the morphological dynamics of astrocytes remains ambiguous....
Sarsasapogenin Improves Pathological Phenotypes in MPTP/MPP+-Induced Parkinson's Disease Models: Synergistic Actions of Neurite Outgrowth, Neurotransmitter Modulation, and Anti-Inflammation [0.03%]
萨斯 Sapogenin 改善 SARS 血清型病理表型:神经突生长、神经递质调节和抗炎作用的协同效应
Wendi Deng,Jinfeng Hong,Weixia Li et al.
Wendi Deng et al.
Background: Parkinson's disease (PD) is a prevalent neurodegenerative disorder hallmarked by progressive loss of midbrain dopaminergic (DA) neurons, neurite atrophy, neurotransmitter imbalance, and motor dysfunction. Ther...
The Efficacy of Experimental Therapy for Stroke Induced by Cerebral Air Embolism in Awake Rats Is Affected by Heliox Inhalation Temperature [0.03%]
氦氧吸入温度影响脑空气栓塞清醒大鼠卒中实验治疗疗效研究
Arina Kholina,Alina Ismailova,Victor Palikov et al.
Arina Kholina et al.
Background: Previous studies have shown that Heliox, a mixture of 32% oxygen and 68% helium administered at a warm temperature, is effective in treating ischemic brain injury caused by cerebral arterial air embolism. At t...
Anticholinergic Burden and Cognitive Function, Depressive Symptoms, and Functional Performance in Individuals With Neurocognitive Disorders: Real-World Evidence [0.03%]
抗胆碱能负担与神经认知障碍患者的认知功能、抑郁症状和功能表现:真实世界证据
Maria Skondra,Leonidas Papadopoulos,Theodora Kougioumtzoglou et al.
Maria Skondra et al.
Background: Despite their negative effects on cognitive function and cognitive decline risk, drugs with anticholinergic properties are commonly prescribed, particularly in older individuals. In this observational study we...
Observational Study
Journal of integrative neuroscience. 2026 Jul 30;25(7):51135. DOI:10.31083/JIN51135 2026
Correction: Zhang et al. Caudate-Centric Triphasic Network Reconfiguration Characterizes the Early Progression of Cognitive Impairment in Parkinson's Disease: A Simultaneous PET/fMRI Study. Journal of Integrative Neuroscience. 2026; 25(2): 46634 [0.03%]
Correction: 张等。底丘脑为中心的三相网络重构表征帕金森病认知障碍早期进展:正电子发射断层扫描/功能磁共振成像联合研究。整合神经科学。2026;25(2): 46634
Wenli Zhang,Guoyang Li,Fengju Mao et al.
Wenli Zhang et al.
Published Erratum
Journal of integrative neuroscience. 2026 Jun 26;25(6):55311. DOI:10.31083/JIN55311 2026
Long-Term Effects of Early Postnatal Administration of R-Baclofen on Neuronal Properties in the Cntnap2 Knockout Rat [0.03%]
早期补脑活肽对Cntnap2基因敲除大鼠长期神经元性质的影响
Hannah Pineda,Susanne Schmid
Hannah Pineda
Background: Contactin-associated protein-like 2 (Cntnap2) is a highly expressed gene during development, coding for the cell adhesion molecule CASPR2. Loss-of-function of Cntnap2 leads to a neurodevelopmental disorder tha...
Efficacy and Safety of Transcranial Direct Current Stimulation on Multiple Health Outcomes in Neurological Disorders: An Umbrella Review of Meta-Analyses of Randomized Controlled Trials [0.03%]
经颅直流电刺激在神经疾病多种结局中的疗效和安全性:随机对照试验的meta分析伞式回顾
Tianfeng Ye,Yuli Shuai,Yiwei Liu et al.
Tianfeng Ye et al.
Background: Neurological disorders are a leading cause of disability worldwide. Transcranial direct current stimulation (tDCS) is a promising therapeutic tool for neurological disorders. However, a consensus on clinical r...