Electroacupuncture Combined With Paroxetine Improves Depression-Like Behavior in Rats by Regulating SIRT2/AMPAR in the Hippocampal Dentate Gyrus [0.03%]
电针联合帕罗西汀通过调控海马齿状回SIRT2/AMPA受体改善大鼠抑郁样行为
Zhinan Zhang,Shengtao Huang,Zheng Li et al.
Zhinan Zhang et al.
Background: Evidence from both clinical trials and animal studies indicates that electroacupuncture (EA) combined with antidepressants is more effective and has fewer side effects in the treatment of depression. In this s...
Bilingual Experience and Functional Neuroplasticity: Insights From Resting-State Functional Connectivity and Functional Network Topology in the Brain [0.03%]
双语经验与功能性神经可塑性：来自大脑静息态功能连接和功能网络拓扑的启示
Yongqiang Jiang,Ling Zhao,Yani Zhang et al.
Yongqiang Jiang et al.
Accumulating evidence has demonstrated that bilingual experience shapes the intrinsic functional organization of the brain. However, the findings from different studies remain fragmented. This review synthesizes resting-state functional mag...
Roles of Metformin and Pioglitazone in Regulating A1-like Astrocyte Activation in EAE Mice [0.03%]
二甲双胍和吡格列酮对EAE小鼠A1样星形胶质细胞活化调控作用的影响研究
Suping Qin,Jingjing Guo,Bohui Yuan et al.
Suping Qin et al.
Background: Neuroinflammation serves as a pivotal driver of pathology in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE) - the widely used animal model of MS. A key contributor to this patholog...
The Lysosomal-Associated Protein Transmembrane Family and Neurological Disorders: Therapeutic Potential and Future Research Directions [0.03%]
溶酶体相关跨膜蛋白家族与神经疾病：治疗潜力及未来研究方向
Zitong Wang,Yang Pan,Min Shu et al.
Zitong Wang et al.
Lysosomal-associated protein transmembrane (LAPTM) family members-including LAPTM4A, LAPTM4B, and LAPTM5-are key regulators of lysosomal integrity, autophagy-lysosome flux, lipid metabolism, and immune responses. Dysregulation of LAPTM prot...
A Capacitance-Based System for Measuring Licking Behaviour in Rodents With Sub-Second Precision [0.03%]
一种基于电容的系统 可对啮齿类动物的舔食行为进行亚秒级精度测量
Yuliia Martynova,José Antonio González
Yuliia Martynova
Background: The ability to measure drinking behaviour in laboratory animals is fundamental for neuroscience and metabolic research. In particular, the analysis of lick microstructure is an important tool for studying inge...
Inter-Hemispheric Asymmetry and Intra-Hemispheric Discrepancy of Electroencephalographic Activities in Patients With Idiopathic Rapid Eye Movement Sleep Behavior Disorder: An Exploratory Study [0.03%]
特发性快速眼动睡眠行为障碍患者的脑电活动的半球间不对称及半球内不一致性：一项探索性研究
Zhijun Zhong,Qi Li,Xueliang Zou et al.
Zhijun Zhong et al.
Background: In idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) patients, electroencephalogram (EEG) activities during REM sleep in some cortical regions are different from those in normal controls. This...
Involvement of the Primary Auditory Cortex-Basolateral Amygdala Circuit in Altered Conditioned Fear Memory Retrieval Following Electromagnetic Field Exposure in Mice [0.03%]
电磁场暴露小鼠听皮层-基底外侧杏仁核环路介导条件性恐惧记忆异常提取作用及相关机制研究
Zhilin Cui,Lei Shi,Meiying Yang et al.
Zhilin Cui et al.
Background: Electromagnetic field (EMF) exposure is increasingly common and has been implicated in a range of effects on human health. Conditioned fear memory plays a critical role in enabling organisms to respond appropr...
FPS-ZM1 Exerts Neuroprotection in Cardiac-Arrest Mice through Inhibiting Oxidative Stress and Pyroptosis via the HMGB1/RAGE Axis [0.03%]
FPS-ZM1通过抑制HMGB1/RAGE轴诱导的氧化应激和pyroptosis对心脏停搏小鼠发挥神经保护作用
Ying Zhu,Qianhui Lin,Yanping Wu et al.
Ying Zhu et al.
Background: Cardiac arrest (CA) is a widespread public health problem with high mortality, severe neurological sequelae, and limited pharmacological therapies. We investigated the neuroprotective effect of a novel drug, F...
The Role of Artificial Intelligence in Diagnosing Acute Ischemic Stroke Using Diffusion MRI: A Multicenter External Validation Study [0.03%]
基于弥散加权MRI诊断急性缺血性卒中的机器学习模型的多中心外部验证研究
Beyza Nur Kuzan,Ali Abbasian Ardakani,Mahmut Esat Aykan et al.
Beyza Nur Kuzan et al.
Background: Acute ischemic stroke is a time-sensitive medical emergency requiring rapid and accurate diagnosis to improve patient outcomes. While Diffusion-Weighted Imaging (DWI) on magnetic resonance imaging (MRI) is hig...
Multicenter Study
Journal of integrative neuroscience. 2026 Apr 21;25(4):48811. DOI:10.31083/JIN48811 2026
Investigating Gender Differences in the Link Between Physical Activity and Depression in Middle-aged and Older Chinese Adults via Network Analysis and Simulation Study [0.03%]
基于网络分析和模拟研究探究中老年人身体活动与抑郁性别差异的关联机制
Ying Xiong,Yiguo Deng,Miao Yu et al.
Ying Xiong et al.
Background: Depression affects 28.4% of middle-aged and older adults globally, exacerbating functional decline, mortality, and healthcare burdens. Physical activity mitigates depression through neurobiological and psychos...