From the Common Cold to a Chaotic Contagion: the Potential for Coronaviruses To Cause Outbreaks of Severe Respiratory Disease Representing a Global Health Threat [0.03%]
从普通感冒到疫情失控：冠状病毒引起严重呼吸道疾病爆发并构成全球健康威胁的潜能
Matthew J Binnicker
Matthew J Binnicker
Coronaviruses are a family of RNA viruses that typically cause mild respiratory disease in humans. However, over the past 20 years, three novel/variant coronaviruses have spilled over from animals into humans and have been associated with s...
Hepatitis A and Hepatitis E: Clinical and Epidemiological Features, Diagnosis, Treatment, and Prevention [0.03%]
肝炎A和E：临床和流行病学特征、诊断、治疗及预防措施
Glynn W Webb,Sophie Kelly,Harry R Dalton
Glynn W Webb
Hepatitis A and E are both ancient diseases but have only been properly recognized as being caused by distinct pathogens in modern times. Despite significantly different genomic structures, both viruses employ remarkably similar strategies ...
Clinically Important Toxins in Bacterial Infection: Utility of Laboratory Detection [0.03%]
细菌感染中有临床意义的毒素：实验室检测的价值
Jessica D Forbes
Jessica D Forbes
The elaboration of proteins that damage host cells is fundamental to the pathogenesis of many bacterial pathogens. The clinical significance of many bacterial toxins is well recognized, and routine detection is necessary to confirm definiti...
Clinical Samples for SARS-CoV-2 Detection: Review of the Early Literature [0.03%]
SARS-CoV-2检测的临床样本：早期文献回顾
Raquel M Martinez
Raquel M Martinez
In January 2020, a cluster of pneumonia cases was reported in Wuhan, China. A global pandemic followed. The infection, called novel coronavirus disease 2019 (COVID-19), is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-...
Matthew A Pettengill
Matthew A Pettengill
Much changed in clinical microbiology in 2019, and, like the organisms, we, as clinical microbiologists, are responsible to detect, characterize, and teach others about our discipline. Also, it is important for us to adapt to changes in the...
Rapid Molecular Panels: What Is in the Best Interest of the Patient? A Review of Patient Outcome Studies for Multiplex Panels Used in Bloodstream, Respiratory, and Neurological Infections [0.03%]
快速分子检测板：何以为患者的最佳选择？综述用于血液流、呼吸道和神经系统感染的多重扩增子检测板患者的结局研究
Kaede V Sullivan
Kaede V Sullivan
In the clinical microbiology laboratory, the focus when choosing new tests is often on performance, turnaround time, and labor needs. This review examines available rapid, multiplexed tests from a different perspective: that of the patient....
Comparison of electronic microarray to enzyme hybridization assay for multiplex reverse-transcriptase PCR detection of common respiratory viruses in children [0.03%]
儿童多重反向 transcription-pcr 检测呼吸道常见病毒的微阵列与酶印迹法比较研究
K J Henrickson,A J Kraft,D Canter et al.
K J Henrickson et al.
A new assay, composed of the NGEN RVA (Nanogen, Inc., San Diego, CA; Prodesse, Inc., Waukesha, WI), which is a pair of analyte-specific reagents that allow the multiplex reverse transcriptase polymerase chain reaction (RT-PCR) and electroni...
Cecile L Tremblay
Cecile L Tremblay