Scratching the surface: The rise of antifungal-resistant dermatophytes [0.03%]
略知皮毛：皮肤真菌的抗真菌耐药性问题不容小觑
Jeremy A W Gold,Shawn R Lockhart
Jeremy A W Gold
Dermatophytosis (also called ringworm or tinea infection) is a common, contagious superficial infection of the skin, hair, or nails caused by dermatophyte molds. Historically, clinicians have considered dermatophytosis as a mild, easy-to-tr...
Shawn R Lockhart,Karlyn Beer,Mitsuru Toda
Shawn R Lockhart
Aspergillosis is one of the most common fungal infections. The predominant cause of aspergillosis is the species Aspergillus fumigatus. There have been increasing reports of A. fumigatus isolates that are resistant to azole antifungals. The...
Shawn R Lockhart
Shawn R Lockhart
Candidemia and candidiasis are among the most frequent healthcare care-associated infections and lead to significant morbidity and mortality. The predominant species causing candidemia remains Candida albicans, but it has declined from the ...
Shawn R Lockhart,Elizabeth L Berkow
Shawn R Lockhart
Antifungal susceptibility testing (AFST) has never been as mainstream as antibacterial susceptibility testing. That may soon change. We are in an unprecedented era of antifungal development which could change the usefulness of and demand fo...
Halie K Miller,Rachael A Priestley,Gilbert J Kersh
Halie K Miller
Q fever is a disease caused by the bacterial pathogen Coxiella burnetii. This hardy organism can easily spread long distances in the wind, and only a few infectious aerosolized particles are necessary to cause serious illness. Presentations...
Monkeypox: Clinical Considerations, Epidemiology, and Laboratory Diagnostics [0.03%]
猴痘：临床考虑、流行病学和实验室诊断
Lucas J Osborn,Diana Villarreal,Noah Wald-Dickler et al.
Lucas J Osborn et al.
Monkeypox virus (MPXV) has garnered recent attention as outbreaks are continually reported outside historic regions of endemicity in Africa. Consequently, MPXV is becoming routinely included in the differential diagnosis of rash illnesses, ...
Clinical Microbiology in 2021: My Favorite Studies about Everything Except My Least Favorite Virus [0.03%]
2021年的临床微生物学：除了我最不喜欢的病毒之外，这是我最喜欢的各类研究
Matthew A Pettengill
Matthew A Pettengill
Maybe 2021 wasn't so bad after all! It was like 2020, but with COVID vaccines and better access to plastic pipette tips, and clearly, 2022 is getting off to a bad start. Even better, 2021 had some exciting papers in clinical microbiology, w...
Herpes Simplex Virus Disease Management and Diagnostics in the Era of High-Throughput Sequencing [0.03%]
高通量测序时代的单纯疱疹病毒疾病管理与诊断
Utsav Pandey,Moriah L Szpara
Utsav Pandey
Herpes simplex virus (HSV) serotypes 1 and 2 are among the most widespread human viruses. HSV disease has a complex phenotype, with symptoms that can range from mild lesions to encephalitis. In the clinical setting, this diversity of outcom...
Severe Acute Respiratory Syndrome Coronavirus 2: The Emergence of Important Genetic Variants and Testing Options for Clinical Laboratories [0.03%]
严重急性呼吸系统综合症冠状病毒2：重要遗传变异体的出现和临床实验室检测选项
Blake W Buchan,Joseph D Yao
Blake W Buchan
Monitoring the spread of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants relies on rapid genetic testing of the viral genome. The sequencing method commonly called next-generation sequencing can identify virus...
Convalescent Plasma for Infectious Diseases: Historical Framework and Use in COVID-19 [0.03%]
传染病的康复期血浆治疗：历史沿革及在新冠中的应用
Juan G Ripoll,Noud van Helmond,Jonathon W Senefeld et al.
Juan G Ripoll et al.
Convalescent plasma has emerged as a promising therapeutic agent for patients with coronavirus disease 2019 (COVID-19), has received emergency use authorization, and is being widely used during the COVID-19 pandemic. Passive antibody therap...