Optical crosstalk in SPAD arrays for high-throughput single-molecule fluorescence spectroscopy [0.03%]
用于高通量单分子荧光光谱的SPAD阵列中的光学串扰
Antonino Ingargiola,Maya Segal,Angelo Gulinatti et al.
Antonino Ingargiola et al.
Single-molecule fluorescence spectroscopy (SMFS), based on the detection of individual molecules freely diffusing through the excitation spot of a confocal microscope, has allowed unprecedented insights into biological processes at the mole...
M T Hassan,F Bateman,B Collett et al.
M T Hassan et al.
Backscatter of electrons from a beta spectrometer, with incomplete energy deposition, can lead to undesirable effects in many types of experiments. We present and discuss the design and operation of a backscatter-suppressed beta spectromete...
Y Xu,G Randers-Pehrson,S A Marino et al.
Y Xu et al.
A horizontal multi-purpose microbeam system with a single electrostatic quadruplet focusing lens has been developed at the Columbia University Radiological Research Accelerator Facility (RARAF). It is coupled with the RARAF 5.5 MV Singleton...
Characterization of Continuous and Pulsed Emission modes of a Hybrid Micro Focus X-ray Source for Medical Imaging Applications [0.03%]
一种混合型微焦点X射线源在医学影像应用中的连续发射和脉冲发射模式表征
Muhammad U Ghani,Molly D Wong,Liqiang Ren et al.
Muhammad U Ghani et al.
The aim of this study was to quantitatively characterize a micro focus x-ray tube that can operate in both continuous and pulsed emission modes. The micro focus x-ray source (Model L9181-06, Hamamatsu Photonics, Japan) has a varying focal s...
AXSIS: Exploring the frontiers in attosecond X-ray science, imaging and spectroscopy [0.03%]
AXSIS：探究阿秒X射线科学研究、成像和光谱学的前沿阵地
F X Kärtner,F Ahr,A-L Calendron et al.
F X Kärtner et al.
X-ray crystallography is one of the main methods to determine atomic-resolution 3D images of the whole spectrum of molecules ranging from small inorganic clusters to large protein complexes consisting of hundred-thousands of atoms that cons...
Preliminary evaluation of a novel energy-resolved photon-counting gamma ray detector [0.03%]
一种新型能量分辨率光子计数伽马射线探测器的初步评估
L-J Meng,J W Tan,K Spartiotis et al.
L-J Meng et al.
In this paper, we present the design and preliminary performance evaluation of a novel energy-resolved photon-counting (ERPC) detector for gamma ray imaging applications. The prototype ERPC detector has an active area of 4.4 cm × 4.4 cm, w...
Estimate interaction timing in a large volume HgI2 detector using cathode pulse waveforms [0.03%]
基于阴极脉冲波形的大体积HgI2探测器相互作用定位研究
L J Meng,Z He
L J Meng
This paper presents experimental results on the timing resolution achieved with a 5 mm thick HgI2 detector. The timing information was derived based on the cathode pre-amplifier pulse waveform, measured using a digital oscilloscope. The tim...
H F-W Sadrozinski,T Geoghegan,E Harvey et al.
H F-W Sadrozinski et al.
We report on the operation and performance tests of a preclinical head scanner developed for proton computed tomography (pCT). After extensive preclinical testing, pCT is intended to be employed in support of proton therapy treatment planni...
A Silicon Photo-multiplier Signal Readout Using Strip-line and Waveform Sampling for Positron Emission Tomography [0.03%]
一种硅光电倍增管信号读出方法用于正电子发射断层扫描
H Kim,C-T Chen,N Eclov et al.
H Kim et al.
A strip-line and waveform sampling based readout is a signal multiplexing method that can efficiently reduce the readout channels while fully exploiting the fast time characteristics of photo-detectors such as the SiPM. We have applied this...
J T Taylor,C Waltham,T Price et al.
J T Taylor et al.
For many years, silicon micro-strip detectors have been successfully used as tracking detectors for particle and nuclear physics experiments. A new application of this technology is to the field of particle therapy where radiotherapy is car...