A systemic review on liquid crystals, nanoformulations and its application for detection and treatment of SARS - CoV- 2 (COVID - 19) [0.03%]
液晶、纳米配方及其在SARS-CoV-2(COVID-19)检测和治疗中的应用的系统性综述
Ayushi Rastogi,Abhilasha Singh,Kaustubh Naik et al.
Ayushi Rastogi et al.
The COVID-19 is a pandemic caused by the SARS-CoV-2 virus, has instigated major health problems and prompted WHO to proclaim a worldwide medical emergency. The knowledge of SARS-CoV-2 fundamental structure, aetiology, its entrance mechanism...
In-silico study for the screening and preparation of ionic liquid-AVDs conjugate to combat COVID-19 surge [0.03%]
计算筛选并制备离子液体-AVDs缀合物以应对新冠肺炎疫情复发的科学研究
Juhi Saraswat,Ufana Riaz,Rajan Patel
Juhi Saraswat
The pandemic due to COVID-19 caused by SARS-CoV-2 has led to the recorded deaths worldwide and is still a matter of concern for scientists to find an effective counteragent. The combination therapy is always been a successful attempt in tre...
Charge-transfer chemistry of two corticosteroids used adjunctively to treat COVID-19. Part I: Complexation of hydrocortisone and dexamethasone donors with DDQ acceptor in five organic solvents [0.03%]
两种用于治疗COVID-19的皮质类固醇的电荷转移化学。第I部分：氢化可的松和地塞米松供体与DDQ受体在五种有机溶剂中的缔合反应
Abdel Majid A Adam,Hosam A Saad,Moamen S Refat et al.
Abdel Majid A Adam et al.
COVID-19 is the disease caused by a novel coronavirus (CoV) named the severe acute respiratory syndrome coronavirus 2 (termed SARS coronavirus 2 or SARS-CoV-2). Since the first case reported in December 2019, infections caused by this novel...
Molecular dynamics simulation approach for discovering potential inhibitors against SARS-CoV-2: A structural review [0.03%]
用于发现SARS-CoV-2潜在抑制剂的分子动力学模拟方法：结构回顾
Shabnam Ghahremanian,Mohammad Mehdi Rashidi,Kimai Raeisi et al.
Shabnam Ghahremanian et al.
Since the commencement of the novel Coronavirus, the disease has quickly turned into a worldwide crisis so that there has been growing attention in discovering possible hit compounds for tackling this pandemic. Discovering standard treatmen...
Machine learning assessment of the binding region as a tool for more efficient computational receptor-ligand docking [0.03%]
机器学习评估结合区域作为更高效的计算受体-配体对接的工具
Matjaž Simončič,Miha Lukšič,Maksym Druchok
Matjaž Simončič
We present a combined computational approach to protein-ligand binding, which consists of two steps: (1) a deep neural network is used to locate a binding region on a target protein, and (2) molecular docking of a ligand is performed within...
Antiviral activities of 4H-chromen-4-one scaffold-containing flavonoids against SARS-CoV-2 using computational and in vitro approaches [0.03%]
基于计算和体外方法的黄酮类化合物抗SARS-CoV-2活性研究
Vinit Raj,Jin-Hyung Lee,Jae-Jin Shim et al.
Vinit Raj et al.
The widespread outbreak of the novel coronavirus called severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused the main health challenge worldwide. This pandemic has attracted the attention of the research communities in va...
Designing AbhiSCoVac - A single potential vaccine for all 'corona culprits': Immunoinformatics and immune simulation approaches [0.03%]
设计AbhiSCoVac疫苗：一种用于所有“冠状病毒罪犯”的潜在通用疫苗——免疫信息学和免疫模拟方法
Abhigyan Choudhury,Parth Sarthi Sen Gupta,Saroj Kumar Panda et al.
Abhigyan Choudhury et al.
The coronaviridae family has generated highly virulent viruses, including the ones responsible for three major pandemics in last two decades with SARS in 2002, MERS outbreak in 2012 and the current nCOVID19 crisis that has turned the world ...
Phase stability of aqueous mixtures of bovine serum albumin with low molecular mass salts in presence of polyethylene glycol [0.03%]
聚乙二醇存在下牛血清白蛋白与低分子量盐的水溶液体系的相行为及稳定性研究
Hurija Džudžević Čančar,Matic Belak Vivod,Vojko Vlachy et al.
Hurija Džudžević Čančar et al.
The stability of bovine serum albumin (BSA) solutions against phase separation caused by cooling the system is studied under the combined influence of added poly(ethylene glycol) (PEG) and alkali halide salts in water as solvent. The phase ...
Mechanistic differences in the effects of sucrose and sucralose on the phase stability of lysozyme solutions [0.03%]
蔗糖和蔗糖醇对溶菌酶溶液相稳定性影响的机制差异
Matjaž Simončič,Miha Lukšič
Matjaž Simončič
The effect of two disaccharide analogues, sucrose and sucralose, on the phase stability of aqueous lysozyme solutions has been addressed from a mechanistic viewpoint by a combination of experiment and molecular dynamics (MD) simulations. Th...
A molecular dynamic study on the ability of phosphorene for designing new sensor for SARS-CoV-2 detection [0.03%]
磷烯设计新的SARS-CoV-2检测传感器的能力的分子动力学研究
Aliyeh Mehranfar,Mohammad Khavani,Mohammad Izadyar
Aliyeh Mehranfar
Due to the dramatic increase in the number of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), designing new selective and sensitive sensors for the detection of this virus is of importance. In this research, by e...