The effect of atypical and classical antipsychotics on sub-chronic PCP-induced cognitive deficits in a reversal-learning paradigm [0.03%]
非典型抗精神病药物和经典抗精神病药对慢性PCP诱导的反转学习范式认知缺损的影响
Z Abdul-Monim,G P Reynolds,J C Neill
Z Abdul-Monim
Phencyclidine (PCP), an NMDA antagonist, has been shown to mimic some aspects of schizophrenia including positive, negative and cognitive symptoms. Previous studies in this laboratory have shown a selective reversal-learning deficit followi...
Comparative Study
Behavioural brain research. 2006 May 15;169(2):263-73. DOI:10.1016/j.bbr.2006.01.019 2006
Comparisons between anxiety tests for selection of anxious and non anxious mice [0.03%]
用于筛选焦虑和非焦虑小鼠的焦虑测试比较
Jean-Claude do-Rego,Alice F Viana,Erwan Le Maître et al.
Jean-Claude do-Rego et al.
Male Swiss albinos mice were submitted to two behavioural tests intended to determine their anxiety level: the elevated plus-maze test as well as the black and white compartments test. In addition they were submitted to the hole-board test....
Comparative Study
Behavioural brain research. 2006 May 15;169(2):282-8. DOI:10.1016/j.bbr.2006.01.018 2006
An animal model of capsular infarct: endothelin-1 injections in the rat [0.03%]
鼷鼠注射内皮素-1所致被膜下梗塞之动物模型
Shawn B Frost,Scott Barbay,Michael L Mumert et al.
Shawn B Frost et al.
In this study stereotaxic injections of the vasoconstrictive peptide endothelin-1 (ET-1) were used to create infarcts in the white matter of the internal capsule underlying sensorimotor cortex in rats. Resulting deficits were assessed using...
Comparative Study
Behavioural brain research. 2006 May 15;169(2):206-11. DOI:10.1016/j.bbr.2006.01.014 2006
Test- and behavior-specific genetic factors affect WKY hypoactivity in tests of emotionality [0.03%]
与测试和行为特异性相关的遗传因素影响WKY品系大鼠在情绪测试中的低活动量
Amber E Baum,Leah C Solberg,Gary A Churchill et al.
Amber E Baum et al.
Inbred Wistar-Kyoto rats consistently display hypoactivity in tests of emotional behavior. We used them to test the hypothesis that the genetic factors underlying the behavioral decision-making process will vary in different environmental c...
Comparative Study
Behavioural brain research. 2006 May 15;169(2):220-30. DOI:10.1016/j.bbr.2006.01.007 2006
Cat odour exposure decreases exploratory activity and alters neuropeptide gene expression in CCK(2) receptor deficient mice, but not in their wild-type littermates [0.03%]
猫气味暴露降低探索行为并改变CCK(2)受体缺陷小鼠而非野生型同窝仔的神经肽基因表达
Tarmo Areda,Sirli Raud,Mari-Anne Philips et al.
Tarmo Areda et al.
An attempt was made to establish whether the anxiogenic effect of cat odour differs in female wild-type and CCK(2) receptor deficient mice, having different exploratory activity in the elevated plus-maze. The exposure of wild-type and homoz...
Comparative Study
Behavioural brain research. 2006 May 15;169(2):212-9. DOI:10.1016/j.bbr.2006.01.010 2006
Further validation of the corridor task for assessing deficit and recovery in the hemi-Parkinsonian rat: restoration of bilateral food retrieval by dopamine receptor agonism [0.03%]
多巴胺受体激动剂恢复半帕金森氏病大鼠双边取食行为的进一步验证研究：在走廊作业条件下评估神经元损伤和修复的新方法
Dominick F Fitzsimmons,Teresa C Moloney,Eilís Dowd
Dominick F Fitzsimmons
The corridor test is a newly developed test of sensorimotor integration that depends on a rat's ability to retrieve food from either side of its body. Rats with unilateral dopamine-depleting lesions neglect food on the contralateral side of...
Comparative Study
Behavioural brain research. 2006 May 15;169(2):352-5. DOI:10.1016/j.bbr.2006.01.013 2006
Chronic nicotine improves working and reference memory performance and reduces hippocampal NGF in aged female rats [0.03%]
慢性尼古丁改善老龄雌性大鼠的工作记忆和参照记忆并减少海马NGF的表达
Kristen L French,Ann-Charlotte E Granholm,Alfred B Moore et al.
Kristen L French et al.
The cholinergic system is involved in cognition and several forms of dementia, including Alzheimer's disease, and nicotine administration has been shown to improve cognitive performance in both humans and rodents. While experiments with hum...
Comparative Study
Behavioural brain research. 2006 May 15;169(2):256-62. DOI:10.1016/j.bbr.2006.01.008 2006
An mRNA expression analysis of stimulation and blockade of 5-HT7 receptors during memory consolidation [0.03%]
5-ht7受体在巩固期间的刺激和阻断过程中的mrna表达分析
Georgina Pérez-García,Claudia Gonzalez-Espinosa,Alfredo Meneses
Georgina Pérez-García
Despite the compelling support for 5-hydroxytryptamine (5-HT) receptors participation in learning and memory in mammal species, the molecular basis had been largely absent from any discussion of its mechanistic underpinnings. Here, we repor...
Comparative Study
Behavioural brain research. 2006 Apr 25;169(1):83-92. DOI:10.1016/j.bbr.2005.12.013 2006
Environmental enrichment increases responding to contextual cues but decreases overall conditioned fear in the rat [0.03%]
环境丰富程度的提高增强了大鼠对情境线索的反应，但降低了整体条件化恐惧程度
A Barbelivien,K Herbeaux,P Oberling et al.
A Barbelivien et al.
This study aimed at investigating the effects of environmental enrichment on various aspects of contextual processing in adult female rats. In experiment 1, simple conditioning was studied using either a training procedure allowing overshad...
Comparative Study
Behavioural brain research. 2006 May 15;169(2):231-8. DOI:10.1016/j.bbr.2006.01.012 2006
Repeated administration of dopaminergic agents in the nucleus accumbens and morphine-induced place preference [0.03%]
多巴胺核团反复给药和吗啡诱导的条件位置偏爱反应
Mohammad-Reza Zarrindast,Bibi-Nasrin Azami,Parvin Rostami et al.
Mohammad-Reza Zarrindast et al.
In the present study, the effects of repeated intra nucleus accumbens (intra-NAc) injections of dopamine receptor agents on morphine-induced conditioned place preference (CPP) in rats were investigated by using an unbiased 3-days schedule o...
Comparative Study
Behavioural brain research. 2006 May 15;169(2):248-55. DOI:10.1016/j.bbr.2006.01.011 2006