Analysis of spatial orientation strategies of male and female Wistar rats in a Morris water escape task [0.03%]
威斯特大鼠在莫里斯水迷宫任务中的空间定向策略的性别差异分析
Arjan Blokland,Kris Rutten,Jos Prickaerts
Arjan Blokland
In the present study we investigated spatial navigation in male and female Wistar rats in the Morris water escape task. Rats were subjected to procedures which required the use of a place (PLACE), cue (CUE) and egocentric (EGO) response to ...
Comparative Study
Behavioural brain research. 2006 Aug 10;171(2):216-24. DOI:10.1016/j.bbr.2006.03.033 2006
Cognitive flexibility but not cognitive coordination is affected in rats with toxic liver failure [0.03%]
急性肝衰大鼠的认知柔韧性而非认知协调性受损
Malgorzata Wesierska,Hanna D Klinowska,Iwona Adamska et al.
Malgorzata Wesierska et al.
Hepatic encephalopathy (HE), a consequence of liver damage, is associated with cognitive deficits. In this study, behavioral activity, non-associative learning, associative memory, cognitive coordination and flexibility were investigated in...
Comparative Study
Behavioural brain research. 2006 Jul 15;171(1):70-7. DOI:10.1016/j.bbr.2006.03.019 2006
Association of paradoxical sleep deprivation and ecstasy (MDMA) enhances genital reflexes in male rats [0.03%]
矛盾睡眠剥夺与 MDMA 的相互作用增强雄性大鼠的生殖器反射反应
M L Andersen,J C Perry,M C Battisti et al.
M L Andersen et al.
Ecstasy ((+/-)3,4-methylenedioxymethamphetamine, MDMA) is a psychostimulant and a synthetic derivative of amphetamine that, according to its consumers, promotes the enhancement of sexual pleasure. This study sought to investigate the effect...
Comparative Study
Behavioural brain research. 2006 Jun 30;170(2):287-92. DOI:10.1016/j.bbr.2006.03.005 2006
Intermale aggression in corticotropin-releasing factor receptor 1 deficient mice [0.03%]
脑室催产素对CRF受体1基因敲除小鼠雄性间攻击行为的影响
Stephen C Gammie,Sharon A Stevenson
Stephen C Gammie
The anxiogenic neuropeptide, corticotropin-releasing factor (CRF), has a complex effect on intermale aggression. CRF receptor 1 (CRFR1) is the primary receptor for CRF and in this study, we examined in detail isolation-induced intermale agg...
Comparative Study
Behavioural brain research. 2006 Jul 15;171(1):63-9. DOI:10.1016/j.bbr.2006.03.017 2006
Adrien Meguerditchian,Jacques Vauclair
Adrien Meguerditchian
Humans are mainly right-handed for many actions including gestures. This bias is strongly linked to a left cerebral hemispheric dominance for language functions. Whether similar lateralized systems for communicative behaviors are present in...
Interleukin-1beta induces anorexia but not spatial learning and memory deficits in the rat [0.03%]
白细胞介素-1β诱导大鼠摄食减少但并不影响空间学习记忆能力
Lisa M Thomson,Robert J Sutherland
Lisa M Thomson
Sickness behaviors are a set of adaptive responses to infection that include lethargy, anorexia, and, of direct relevance to this work, learning and memory impairments. The proinflammatory cytokine, interleukin-1 beta (IL-1beta) has been pr...
Comparative Study
Behavioural brain research. 2006 Jun 30;170(2):302-7. DOI:10.1016/j.bbr.2006.03.004 2006
Coenzyme Q10 modulates cognitive impairment against intracerebroventricular injection of streptozotocin in rats [0.03%]
辅酶Q10调节链脲佐菌素脑室内注射大鼠认知障碍的作用及机制研究
Tauheed Ishrat,M Badruzzaman Khan,Md Nasrul Hoda et al.
Tauheed Ishrat et al.
Coenzyme Q10 (CoQ10), a peculiar lipophilic antioxidant, is an essential component of the mitochondrial electron-transport chain. It is involved in the manufacturing of adenosine triphosphate (ATP) and has been linked with improving cogniti...
Comparative Study
Behavioural brain research. 2006 Jul 15;171(1):9-16. DOI:10.1016/j.bbr.2006.03.009 2006
Retrosplenial cortex lesions impair water maze strategies learning or spatial place learning depending on prior experience of the rat [0.03%]
后脾旁皮层损伤影响大鼠水迷宫策略学习或空间位置学习取决于其先前经验
Donald P Cain,Richard Humpartzoomian,Francis Boon
Donald P Cain
There has been debate whether lesions strictly limited to retrosplenial (RS) cortex impair spatial navigation, and how robust and reliable any such impairment is. The present study used a detailed behavioral analysis with naive or strategie...
Comparative Study
Behavioural brain research. 2006 Jun 30;170(2):316-25. DOI:10.1016/j.bbr.2006.03.003 2006
Rat/mouse hemokinin-1, a mammalian tachykinin peptide, markedly potentiates the antinociceptive effects of morphine administered at the peripheral and supraspinal level [0.03%]
大鼠/小鼠血栓素-1(一种哺乳动物的多肽激动剂),通过外周和脑内的给药,能够显著增强阿片类药物的镇痛效果
Cai-Yun Fu,Qi Yang,Kai-Rong Wang et al.
Cai-Yun Fu et al.
Rat/mouse hemokinin 1 (r/m HK-1) is a mammalian tachykinin peptide whose biological functions are not fully understood. Our recent report showed that i.c.v. administration of r/m HK-1 could produce dose- and time-related antinociceptive eff...
Comparative Study
Behavioural brain research. 2006 Jun 30;170(2):293-301. DOI:10.1016/j.bbr.2006.03.007 2006
Dynorphin A (1-13) and responsiveness of the newborn rat to a surrogate nipple: immediate behavioral consequences and reinforcement effects in conditioning [0.03%]
dynorphin A(1-13)与新生大鼠对乳头替代物的反应:即时行为后果及其在条件反射中的强化作用
Evgeniy S Petrov,Michael E Nizhnikov,Elena I Varlinskaya et al.
Evgeniy S Petrov et al.
The role of endogenous opioid system in learning (Pavlovian conditioning) and reinforcement was studied in newborn rats by pairing central injection of dynorphin A (1-13), an endogenous ligand with high affinity for kappa opioid receptors, ...