Compromised circadian function in Parkinson's disease: enucleation augments disease severity in the unilateral model [0.03%]
帕金森病的昼夜功能障碍：视神经切除加重单侧模型病情
Gregory L Willis,Adelheid M A Kelly,Gerard A Kennedy
Gregory L Willis
Like enucleation, lateral hypothalamic (LH) lesions sever the connection between the retina and the pineal thereby simulating ambient exposure to constant darkness. While LH lesions have been employed to study either circadian function or P...
Laura Jiménez Ortega,Katrin Stoppa,Onur Güntürkün et al.
Laura Jiménez Ortega et al.
The retina of the pigeon has two areas of enhanced vision: the red field looking into the frontal binocular field and the yellow field projecting into the lateral monocular field. The entire retina projects to the tectofugal pathway, wherea...
Effects of bilateral vestibular deafferentation on anxiety-related behaviours in Wistar rats [0.03%]
双侧前庭神经切断对Wistar大鼠焦虑样行为的影响
Yiwen Zheng,Matthew Goddard,Cynthia L Darlington et al.
Yiwen Zheng et al.
Despite frequent reports that patients with vestibular dysfunction exhibit an unusually high incidence of anxiety disorders, few studies have investigated the emotional effects of vestibular damage in animals. In this study we investigated ...
Different housing conditions alter the behavioural phenotype of CCK(2) receptor-deficient mice [0.03%]
不同的饲养条件改变CCK(2)受体基因敲除小鼠的行为表型
Urho Abramov,Sirli Raud,Jürgen Innos et al.
Urho Abramov et al.
The behavioural phenotype of mice, lacking CCK(2) receptors, has varied across studies conducted not only in different laboratories, but also across studies published by the same laboratory. The present study was designed to elucidate the p...
Withdrawal emotional-regulation in infant rats from genetic animal models of depression [0.03%]
抑郁症基因动物模型幼鼠的撤药情绪反应调节能力研究
Y Braw,O Malkesman,A Merenlender et al.
Y Braw et al.
Children of depressed parents exhibit high rates of emotion-dysregulation, characterized by excessive withdrawal or approach strategies toward the mother in infancy. The understanding of factors affecting the establishment of these behavior...
Mijail Demian Serruya,Michael J Kahana
Mijail Demian Serruya
Executive planning, the ability to direct and sustain attention, language and several types of memory may be compromised by conditions such as stroke, traumatic brain injury, cancer, autism, cerebral palsy and Alzheimer's disease. No medica...
Nature vs. nurture: can enrichment rescue the behavioural phenotype of BDNF heterozygous mice? [0.03%]
环境与遗传：富养能改善BDNF杂合小鼠的行为表型吗？
Sabine Chourbaji,Christiane Brandwein,Miriam A Vogt et al.
Sabine Chourbaji et al.
In earlier experiments we have demonstrated that group-housing in a rather impoverished "standard" environment can be a crucial stress factor in male C57Bl/6 mice. The present study aimed at investigating the effect of combining a probable ...
Comparative Study
Behavioural brain research. 2008 Oct 10;192(2):254-8. DOI:10.1016/j.bbr.2008.04.015 2008
Impulsive choice and environmental enrichment: effects of d-amphetamine and methylphenidate [0.03%]
关于安非他明和甲基苯丙胺的行为学研究：冲动选择与环境丰富度的关系
Jennifer L Perry,Dustin J Stairs,Michael T Bardo
Jennifer L Perry
Individual differences in impulsive choice and rearing in differential environments are factors that predict vulnerability to drug abuse. The present study determined if rearing influences impulsive choice, and if d-amphetamine or methylphe...
The effects of overtraining in the Morris water maze on allocentric and egocentric learning strategies in rats [0.03%]
Morris水迷宫过训练对大鼠allo-centric和ego-centric学习策略的影响
John Kealy,Mairead Diviney,Elizabeth Kehoe et al.
John Kealy et al.
Animals can use both allocentric and egocentric strategies to learn a spatial task. Our results suggest that allocentric cues are more dominant than idiothetic cues in guiding navigation. Animals do not necessarily learn an egocentric strat...
Trial-selective effects of U50,488H, a kappa-opioid receptor agonist, on consummatory successive negative contrast [0.03%]
κ-阿片受体激动剂U50,488H对摄取式连续负强化的试验选择效应
Michael D Wood,Jacob N Norris,Alan M Daniel et al.
Michael D Wood et al.
A series of experiments studied the effects of the kappa-opioid receptor agonist U50,488H on consummatory successive negative contrast (cSNC) in rats. In cSNC, previous experience with a 32% sucrose solution leads to greater rejection of 4%...