Nicola Grissom,Wesley Kerr,Seema Bhatnagar
Nicola Grissom
Restraint elicits a number of physiological stress responses that can be increased or decreased in magnitude based on prior stress history. For instance, repeated exposure to restraint leads to habituation of hypothalamic-pituitary-adrenal ...
Long-term consequences of soman poisoning in mice: part 2. Emotional behavior [0.03%]
沙林中毒的长期后果(第二部分):情绪行为
Stéphanie Coubard,Daniel Béracochéa,Jean-Marc Collombet et al.
Stéphanie Coubard et al.
The organophosphorus compound soman produces long-lasting epileptic seizure activity which is associated to brain damage, more particularly in the hippocampus and the amygdala. The companion paper (see part 1 in the same journal issue) desc...
Basolateral amygdala lesions and sensitivity to reinforcer magnitude in concurrent chains schedules [0.03%]
基底外侧杏仁核损伤对并发链式强化敏感性的影响
Christa M Helms,Suzanne H Mitchell
Christa M Helms
Previous studies show that the basolateral amygdala (BLA) is required for behavior to adjust when the value of a reinforcer decreases after satiation or pairing with gastric distress. This study evaluated the effect of pre- or post-training...
Altered water-maze search behavior in adult guinea pigs following chronic prenatal ethanol exposure: lack of mitigation by postnatal fluoxetine treatment [0.03%]
慢性宫内酒精暴露后成年 Guinea Pig 在水迷宫中的搜索行为改变:产后氟西汀治疗无改善作用
Teresa D McAdam,James F Brien,James N Reynolds et al.
Teresa D McAdam et al.
Ingestion of ethanol during pregnancy can result in teratogenic effects in humans, including significant and long-lasting neurobehavioral deficits. Similar results are seen in guinea pigs with chronic prenatal ethanol exposure (CPEE) via ma...
A necessary role for GluR1 serine 831 phosphorylation in appetitive incentive learning [0.03%]
GluR1丝氨酸831磷酸化在正向诱惑性学习中的作用
Hans S Crombag,Jeffrey M Sutton,Kogo Takamiya et al.
Hans S Crombag et al.
It is widely thought that regulation of post-synaptic AMPA receptors is a critical component in changes in synaptic efficacy underlying learning and memory. The regulation of AMPA receptors occurs through trafficking of the receptor and/or ...
Improvement of phencyclidine-induced social behaviour deficits in rats: involvement of 5-HT1A receptors [0.03%]
苯环己哌啶致大鼠社会行为缺损的改善及五羟色胺1A受体的作用
Shikha Snigdha,Joanna C Neill
Shikha Snigdha
We have recently shown that sub-chronic phencyclidine (PCP) treatment produces social behaviour deficits in female rats which are reversed by ziprasidone but not haloperidol or clozapine. This investigation was designed to extend the previo...
Anxiety-like behaviour in adult rats perinatally exposed to maternal calorie restriction [0.03%]
孕期母体热量摄入量不足导致后代成人期出现类似焦虑的行为反应
Elizabeth A Levay,Antonio G Paolini,Antonina Govic et al.
Elizabeth A Levay et al.
Environmental stimuli such as caloric availability during the perinatal period exert a profound influence on the development of an organism. Studies in this domain have focused on the effects of under- and malnutrition while the effects of ...
Open field locomotor activity and anxiety-related behaviors in mucopolysaccharidosis type IIIA mice [0.03%]
III型黏多糖贮积症小鼠的旷场活动和焦虑相关行为
Adeline A Lau,Allison C Crawley,John J Hopwood et al.
Adeline A Lau et al.
Mucopolysaccharidosis (MPS) IIIA, or Sanfilippo syndrome, is a lysosomal storage disorder characterized by severe and progressive neuropathology. Following an asymptomatic period, patients may present with sleep disturbances, cognitive decl...
Estradiol decreases the orexigenic effect of neuropeptide Y, but not agouti-related protein, in ovariectomized rats [0.03%]
雌二醇降低雌鼠下视丘弧蛋白对摄食的刺激作用但不影响黑皮质素受体-4的效果
Jessica Santollo,Lisa A Eckel
Jessica Santollo
Available data suggest that estradiol exerts an inhibitory effect on food intake by modulating the actions of multiple gut- and brain-derived peptides implicated in the control of food intake. For example, recent studies have shown that est...
Sheryl S Moy,Jessica J Nadler,Nancy B Young et al.
Sheryl S Moy et al.
Core symptoms of autism include deficits in social interaction, impaired communication, and restricted, repetitive behaviors. The repetitive behavior domain encompasses abnormal motoric stereotypy, an inflexible insistence on sameness, and ...