Effect of disconnecting the orbital prefrontal cortex from the nucleus accumbens core on inter-temporal choice behaviour: a quantitative analysis [0.03%]
分离轨道前额皮层与背侧纹状体核对跨时间选择行为的影响：定量分析
G Bezzina,S Body,T H C Cheung et al.
G Bezzina et al.
Previous experiments showed that destruction of the orbital prefrontal cortex (OPFC) or the nucleus accumbens core (AcbC) in rats altered choice between two delayed food reinforcers. Application of a quantitative model of inter-temporal cho...
MGlu5 antagonism impairs exploration and memory of spatial and non-spatial stimuli in rats [0.03%]
metabotropic glutamate 5受体拮抗剂引起大鼠对空间及非空间刺激探索和记忆的缺失
Gert R J Christoffersen,Agnes Simonyi,Todd R Schachtman et al.
Gert R J Christoffersen et al.
Metabotropic glutamate receptor subtype 5 (mGlu5) has been implicated in memory processing in some but not all learning tasks. The reason why this receptor is involved in some tasks but not in others remains to be determined. The present ex...
Novelty-induced behavioral traits correlate with numbers of brainstem noradrenergic neurons and septal cholinergic neurons in C57BL/6J mice [0.03%]
新颖性诱导的行为表型与C57BL/6J小鼠脑干去甲肾上腺素能神经元和隔区胆碱能神经元数量相关
Yuliya Tereshchenko,Joerg Brandewiede,Melitta Schachner et al.
Yuliya Tereshchenko et al.
It is generally accepted that different brain regions regulate specific behavioral responses and that structural alterations in these regions may affect behavior. We investigated whether inter-individual variability in novelty-induced behav...
Response properties of avian hippocampal formation cells in an environment with unstable goal locations [0.03%]
不稳定目标位置环境下鸟类海马结构细胞的反应性质
Meghan C Kahn,Jennifer J Siegel,Tammy J Jechura et al.
Meghan C Kahn et al.
The response properties of 48 right (n=24) and left (n=24) hippocampal formation (HF) cells were examined by recording from freely moving homing pigeons as they foraged in an open-field environment with unstable goal locations. Compared to ...
The impact of voluntary exercise on mental health in rodents: a neuroplasticity perspective [0.03%]
从神经可塑性角度浅谈运动对啮齿类动物心理状态的影响
Susanna Pietropaolo,Yan Sun,Ruixi Li et al.
Susanna Pietropaolo et al.
There is growing interest in the effects of voluntary wheel running activity on brain and behaviour in laboratory rodents and their implications to humans. Here, the major findings to date on the impact of exercise on mental health and dise...
Raquel C R Martinez,Eduardo F Carvalho-Netto,Vanessa C S Amaral et al.
Raquel C R Martinez et al.
The hypothalamus plays especially important roles in various endocrine, autonomic, and behavioral responses that guarantee the survival of both the individual and the species. In the rat, a distinct hypothalamic defensive circuit has been d...
Maternal separation and maternal care act independently on the development of HPA responses in male rats [0.03%]
母系隔离和母系关怀独立作用于雄性大鼠HPA反应的发育过程
Simone Macrì,Flavia Chiarotti,Hanno Würbel
Simone Macrì
Postnatal manipulations such as brief (early handling, EH) and long, daily mother-offspring separations (maternal separation, MS) in rats are used to study the mechanisms underlying developmental plasticity of stress and fear responses, and...
Differential amygdala activation to negative and positive emotional pictures during an indirect task [0.03%]
间接任务中积极和消极图片诱发的杏仁核激活差异
Thomas Straube,Sebastian Pohlack,Hans J Mentzel et al.
Thomas Straube et al.
The role of the amygdala for the processing of valence and arousal is a matter of debate. Using event-related functional magnetic resonance imaging, we tested valence-specific amygdala effects during attentional distraction. Subjects attend...
Increased locomotor activity in mice lacking the low-density lipoprotein receptor [0.03%]
缺乏低密度脂蛋白受体的小鼠的运动活动增加
Gregory A Elder,Andre Ragnauth,Nathan Dorr et al.
Gregory A Elder et al.
While the low-density lipoprotein receptor (LDLR) is best known for its role in regulating serum cholesterol, LDLR is expressed in brain, suggesting that it may play a role in CNS function as well. Here, using mice with a null mutation in L...
The serotonin 5-HT7 receptor agonist LP-44 microinjected into the dorsal raphe nucleus suppresses REM sleep in the rat [0.03%]
腹侧被盖区注射LP-44通过作用于5-HT7受体抑制大鼠REM睡眠
Jaime M Monti,Marcello Leopoldo,Héctor Jantos
Jaime M Monti
The effects of LP-44, a selective 5-HT7 receptor agonist, and of SB-269970, a selective 5-HT7 receptor antagonist, on spontaneous sleep were studied in adult rats implanted for chronic sleep recordings. The 5-HT7 receptor ligands were micro...