Ischemia-induced hyperactivity: effects of dim versus bright illumination on open-field exploration and habituation following global ischemia in rats [0.03%]
缺血引起的超活性：不同光照条件下全脑缺血对大鼠开放式旷场探索及习惯化的影响
Marc Milot,Hélène Plamondon
Marc Milot
The current study reports the impact of different illumination conditions on exploratory activity following global ischemia in rats. Exploratory activity was tested at different post-ischemic intervals under bright (450 lux) or dim (40 lux)...
Early detection of memory deficits and memory improvement with vaccinia virus complement control protein in an Alzheimer's disease model [0.03%]
痘苗病毒补体控制蛋白早期检测记忆缺陷和改善记忆力的阿尔茨海默病模型中
Nirvana S Pillay,Laurie A Kellaway,Girish J Kotwal
Nirvana S Pillay
Vaccinia virus complement control protein (VCP) inhibits both the classical and alternate complement pathways. In diseases such as traumatic brain injury (TBI) and Alzheimer's disease (AD), pathological inflammation is caused by amongst sev...
Amphetamine sensitization in rats as an animal model of schizophrenia [0.03%]
作为精神分裂症动物模型的氨甲酰胺类药物在大鼠体内敏感性增强现象
D Peleg-Raibstein,I Knuesel,J Feldon
D Peleg-Raibstein
Based on the 'endogenous dopamine sensitization' hypothesis of schizophrenia the present study employed a repeated amphetamine administration regime in order to investigate the behavioral, neurochemical and neuroanatomical consequences foll...
Injection of CART (cocaine- and amphetamine-regulated transcript) peptide into the nucleus accumbens reduces cocaine self-administration in rats [0.03%]
卡特(CART，可卡因和苯丙胺调节转录产物)肽注射到伏隔核减少大鼠的可卡因自我给药行为
Jason N Jaworski,Stephen T Hansen,Michael J Kuhar et al.
Jason N Jaworski et al.
Cocaine- and amphetamine-regulated transcript (CART) peptides appear to modulate various effects of psychostimulant drugs. Injections of CART peptide into the nucleus accumbens (NAcc) inhibit locomotion produced by systemic injections of th...
Combining TMS and EEG to study cognitive function and cortico-cortico interactions [0.03%]
结合经颅磁刺激和脑电研究认知功能及皮层间相互作用
Paul C J Taylor,Vincent Walsh,Martin Eimer
Paul C J Taylor
There has long been an interest in exploring the functional dynamics of the brain's connectivity during cognitive processing, and some recent methodological developments now allow us to test important long-standing hypotheses. This review f...
Long-term prevention of Alzheimer's disease-like behavioral deficits in PDAPP mice carrying a mutation in Asp664 [0.03%]
携带Asp664突变的PDAPP小鼠长期预防类似阿尔茨海默病的行为缺陷
Veronica Galvan,Junli Zhang,Olivia F Gorostiza et al.
Veronica Galvan et al.
The deficits of Alzheimer's disease (AD) are believed to result, at least in part, from neurotoxicity of beta-amyloid (Abeta), a set of 38-43 amino acid fragments derived from the beta-amyloid precursor protein (APP). In addition, APP gener...
Phencyclidine-induced locomotor hyperactivity is enhanced in mice after stereotaxic brain serotonin depletion [0.03%]
脑立体定位技术耗竭5-ht后小鼠所致苯环己哌啶致运动过度作用增强
Sally Martin,Maarten van den Buuse
Sally Martin
The aim of this study was to investigate the role of forebrain serotonin projections in behavioural models with relevance to schizophrenia. Mice received stereotaxic micro-injections of the serotonin neurotoxin 5,7-dihydroxytryptamine into ...
Phencyclidine-induced locomotor hyperactivity is enhanced in mice after stereotaxic brain serotonin depletion [0.03%]
脑立体定位技术耗损脑内5-HT增强磷甲酚丁因所诱导之小鼠过度自发放行动行为反应
Sally Martin,Maarten van den Buuse
Sally Martin
The aim of this study was to investigate the role of forebrain serotonin projections in behavioural models with relevance to schizophrenia. Mice received stereotaxic micro-injections of the serotonin neurotoxin 5,7-dihydroxytryptamine into ...
Matthieu J Guitton,Yael Klin,Yadin Dudai
Matthieu J Guitton
Using a combination of the paradigm of conditioned taste aversion (CTA) and of the paradigm of social interactions, we report here that in the rat, eating while anxious may result in long-term alterations in social behavior. In the conventi...
Lilianne Manning
Lilianne Manning
Paillard [Paillard J. Réflexions sur l'usage du concept de plasticité en Neurobiologie. J Psychol Norm Pathol 1976;1:33-47] defined adaptive plasticity as the capacity of the system to change its own structure and expand its behavioural r...