Disturbances in social interaction occur along with pathophysiological deficits following sub-chronic phencyclidine administration in the rat [0.03%]
次急性氯胺酮处理后大鼠的社会交互受损与病理生理缺陷有关
Trisha A Jenkins,Michael K Harte,Claire E McKibben et al.
Trisha A Jenkins et al.
A sub-chronic administration of phencyclidine to the rat brings about enduring pathophysiological and cognitive changes that resemble some features of schizophrenia. The present study aimed to determine whether the behavioural consequence o...
Stimulation of dopamine D1 receptors in the avian fronto-striatal system adjusts daily cognitive fluctuations [0.03%]
鸟类纹状体系统中多巴胺D1受体的刺激调节日常认知变化
Christina Herold,Bettina Diekamp,Onur Güntürkün
Christina Herold
Several studies have shown that the level of dopaminergic transmission and D1 receptor signaling is crucial for working memory (WM) in the prefrontal cortex (PFC) of mammals. Thus, hyper- or hypostimulation of prefrontal D1 receptors are pa...
Patrizia Thoma,Benno Koch,Katrin Heyder et al.
Patrizia Thoma et al.
The involvement of the prefrontal cortex in executive control has been well established. It is, however, as yet unclear whether the basal ganglia and the cerebellum as components of frontostriatal/frontocerebellar networks also contribute t...
Memory is differently impaired during aging according to the learning tasks in the rat [0.03%]
大鼠在老化过程中学习任务不同记忆损伤也不同
David Dardou,Frédérique Datiche,Martine Cattarelli
David Dardou
The aim of the present study was to determine the impact of aging on learning and retrieval of taste-potentiated odor aversion (TPOA). TPOA, which involves processing of odor, gustatory, and visceral cues, is a particular form of learning i...
Bilateral impairments of skilled reach-to-eat in early Parkinson's disease patients presenting with unilateral or asymmetrical symptoms [0.03%]
早期帕金森病患者受累侧不同的一侧或非对称性症状的灵巧取食动作障碍研究
Jon B Doan,Kyle G Melvin,Ian Q Whishaw et al.
Jon B Doan et al.
Previous studies have described limb and hand movement abnormalities in a reach-to-eat task in advanced Parkinson's disease (PD) and animal models of PD. The present study was directed toward examining reach-to-eat movements in early PD pat...
Lesions of the entorhinal cortex or fornix disrupt the context-dependence of fear extinction in rats [0.03%]
损毁海马纹或穹窿破坏大鼠恐惧消退的背景依赖性现象
Jinzhao Ji,Stephen Maren
Jinzhao Ji
Recent studies have shown that the hippocampus is critical for the context-dependent expression of extinguished fear memories. Here we used Pavlovian fear conditioning in rats to explore whether the entorhinal cortex and fornix, which are t...
The partial reinforcement extinction effect (PREE) in female Roman high- (RHA-I) and low-avoidance (RLA-I) rats [0.03%]
低回避和高回避罗马大鼠的不完全强化消退效应研究
M A José Gómez,Lourdes de la Torre,José Enrique Callejas-Aguilera et al.
M A José Gómez et al.
The present experiment was designed with the goal of studying the partial reinforcement extinction effect (PREE) in female inbred Roman high- (RHA-I) and low-avoidance (RLA-I) rats. Two groups of RHA-I and two of RLA-I food-deprived animals...
Post-training progesterone dose-dependently enhances object, but not spatial, memory consolidation [0.03%]
Lauren L Harburger,Angela S Pechenino,Altaf Saadi et al.
Lauren L Harburger et al.
The aim of this study was to determine if progesterone modulates object and spatial memory consolidation in young ovariectomized C57BL/6 mice. Object memory was tested in an object recognition task using 24- and 48-h delays. Spatial memory ...
Ran Harel,Itay Asher,Oren Cohen et al.
Ran Harel et al.
Performing voluntary motor actions requires the translation of motor commands into a specific set of muscle activation. While it is assumed that this process is carried out via cooperative interactions between supraspinal and spinal neurons...
Dynamic visual information plays a critical role for spatial navigation in water but not on solid ground [0.03%]
Chiara Sajidha Sautter,Luca Cocchi,Françoise Schenk
Chiara Sajidha Sautter
In the Morris water maze (MWM) task, proprioceptive information is likely to have a poor accuracy due to movement inertia. Hence, in this condition, dynamic visual information providing information on linear and angular acceleration would p...