Dexterous movement complexity and cerebellar activation: a meta-analysis [0.03%]
灵巧运动的复杂性与小脑激活之间的关系： META 分析
Raymond C K Chan,Jia Huang,Xin Di
Raymond C K Chan
The importance of the cerebellum in coordinates of movement has been established by lesion studies. However, there is no clear understanding of whether there is consistent activation in cerebellum across various motor task complexities or h...
K Fuxe,L F Agnati,F Mora
K Fuxe
The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies [0.03%]
卡路里限制、酮体饮食和酮体的神经保护特性
Marwan Maalouf,Jong M Rho,Mark P Mattson
Marwan Maalouf
Both calorie restriction and the ketogenic diet possess broad therapeutic potential in various clinical settings and in various animal models of neurological disease. Following calorie restriction or consumption of a ketogenic diet, there i...
Eitan Okun,Kathleen J Griffioen,Justin D Lathia et al.
Eitan Okun et al.
The key roles of toll-like receptors (TLRs) as mediators of the detection and responses of immune cells to invading pathogens are well known. There are at least 13 mammalian TLRs which are integral membrane proteins with a leucine-rich extr...
Intracellular degradation of misfolded proteins in polyglutamine neurodegenerative diseases [0.03%]
聚谷氨酰胺神经退行性疾病中细胞内错误折叠蛋白的降解
Xiang Li,He Li,Xiao-Jiang Li
Xiang Li
A number of neurodegenerative diseases, including Alzheimer's, Parkinson's, and polyglutamine diseases, are characterized by the age-dependent formation of intracellular protein aggregates and neurodegeneration. Although there is some debat...
Neurobiological mechanisms of the reinstatement of drug-conditioned place preference [0.03%]
药物条件位置偏好的复摄神经生物学机制
Maria A Aguilar,Marta Rodríguez-Arias,Jose Miñarro
Maria A Aguilar
Drug addiction is a chronic disorder characterized by a high rate of relapse following detoxification. There are two main versions of the reinstatement model that are employed to study relapse to drug abuse; one based on the operant self-ad...
Spontaneous neuronal burst discharges as dependent and independent variables in the maturation of cerebral cortex tissue cultured in vitro: a review of activity-dependent studies in live 'model' systems for the development of intrinsically generated bioelectric slow-wave sleep patterns [0.03%]
体外培养脑皮质组织成熟的自发神经元簇状放电的因变量和自变量：发育中内在生成生物电慢波睡眠模式活“模型”系统的活动依赖性研究综述
Michael A Corner
Michael A Corner
A survey is presented of recent experiments which utilize spontaneous neuronal spike trains as dependent and/or independent variables in developing cerebral cortex cultures when synaptic transmission is interfered with for varying periods o...
New insights into brain BDNF function in normal aging and Alzheimer disease [0.03%]
脑源性神经营养因子在正常衰老和阿尔茨海默病中的新见解
Lucia Tapia-Arancibia,Esteban Aliaga,Michelle Silhol et al.
Lucia Tapia-Arancibia et al.
The decline observed during aging involves multiple factors that influence several systems. It is the case for learning and memory processes which are severely reduced with aging. It is admitted that these cognitive effects result from impa...
The acute effects of NMDA antagonism: from the rodent to the human brain [0.03%]
NMDA受体拮抗的急性效应：从小鼠脑到人脑
Handan Gunduz-Bruce
Handan Gunduz-Bruce
In the past decade, the N-methyl-d-aspartate receptor (NMDAR) hypofunction hypothesis of schizophrenia has received support from several lines of clinical evidence, including genetic, postmortem and human psychosis modeling. Recently, super...
The role of the cerebellum in the pathophysiology and treatment of neuropsychiatric disorders: a review [0.03%]
小脑在神经精神障碍的病理生理和治疗中的作用：综述性文章
Sylco S Hoppenbrouwers,Dennis J L G Schutter,Paul B Fitzgerald et al.
Sylco S Hoppenbrouwers et al.
The cerebellum has traditionally been looked upon as a brain area primarily involved in motor behaviour. The last decade has however heralded the cerebellum as a brain region of renewed interest for neuropsychiatric disorders. This renewed ...